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01-09-2019 | Alzheimer's Disease | Psychiatry and Preclinical Psychiatric Studies - Review Article

Stress and Alzheimer’s disease

Authors: Claus M. Escher, Lena Sannemann, Frank Jessen

Published in: Journal of Neural Transmission | Issue 9/2019

Abstract

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Due to demographic change in higher income countries and rising life expectancy in middle- and low-income countries, the prevalence of AD will increase significantly in the coming years. In the search for effective AD prevention, the role of stress in the development of AD has come into focus. There is increasing evidence that chronic exposure to stress is a risk factor for AD and may also adversely affect the course of the disease. In our review, we present the current literature on the association of specific personality traits and the risk of developing AD. We also report on findings on dementia risk in patients with posttraumatic stress disorder. Furthermore, we describe the role of anxiety symptoms in AD and give a brief overview over the biological mechanisms behind the association of stress and AD.

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Title: Stress and Alzheimer’s disease
Authors: Claus M. Escher
Lena Sannemann
Frank Jessen
Publication date: 01-09-2019
Publisher: Springer Vienna
Keywords: Alzheimer's Disease
Dementia
Alzheimer's Disease
Dementia
Mild Neurocognitive Disorder
Anxiety
Published in: Journal of Neural Transmission / Issue 9/2019
Print ISSN: 0300-9564
Electronic ISSN: 1435-1463
DOI: https://doi.org/10.1007/s00702-019-01988-z

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Stress and Alzheimer’s disease

Abstract

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Abstract

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