Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
AIDS and Behavior
Published in: AIDS and Behavior 4/2008

01-07-2008 | Original Paper

Alcohol Use, Depressive Symptoms and the Receipt of Antiretroviral Therapy in Southwest Uganda

Authors: Priscilla Martinez, Irene Andia, Nneka Emenyonu, Judith A. Hahn, Edvard Hauff, Larry Pepper, David R. Bangsberg

Published in: AIDS and Behavior | Issue 4/2008

Login to get access

Abstract

Alcohol use and depressive symptoms are associated with reduced access to antiretroviral therapy (ART) in the developed world. Whether alcohol use and depressive symptoms limit access to ART in resource-limited settings is unknown. This cross-sectional study examined the association between alcohol use, depressive symptoms and the receipt of ART among randomly selected HIV-positive persons presenting for primary health care services at an outpatient HIV clinic in Uganda. Depressive symptoms were defined by the Hopkins Symptom Checklist and alcohol use was measured through frequency of consumption questions. Antiretroviral use was assessed using a standardized survey and confirmed by medical record review. Predictors of ART use were determined via logistic regression. Among 421 HIV-infected patients, factors associated with the receipt of ART were having at least primary education, having an opportunistic infection in the last 3 months, and not drinking within the last year.
Literature
Alexandre, P. K., Roebuck, M. C., French, M. T., Chitwood, D. D., & Mccoy, C. B. (2001). Problem drinking, health services utilization, and the cost of medical care. Recent Developments in Alcoholism, 15, 285–298.PubMedCrossRef
Antelman, G., Kaaya, S., Wei, R., Mbwambo, J., Msamanga, G. I., Fawzi, W. W., & Fawzi, M. C. (2007). Depressive symptoms increase risk of HIV disease progression and mortality among women in Tanzania. Journal of Acquired Immune Deficiency Syndromes, 44, 470–477.PubMedCrossRef
Babor, T. F., de la Fuente, J. R., Saunders, J. B., & Grant, M. (1992). AUDIT—The alcohol use disorders identification test: Guidelines for use in primary health care (1st ed.). Geneva: World Health Organization.
Babor, T. F., Higgins-Biddle, J. C., Saunders, J. B., & Monteiro, M. G. (2001). The alcohol use disorders identification test: Guidelines for use in primary care (2nd ed.). Geneva: World Health Organization.
Bing, E. G., Burnam, M. A., Longshore, D., Fleishman, J. A., Sherbourne, C. D., London, A. S., Turner, B. J., Eggan, F., Beckman, R., Vitiello, B., Morton, S. C., Orlando, M., Bozzette, S. A., Ortiz-Barron, L., & Shapiro, M. (2001). Psychiatric disorders and drug use among human immunodeficiency virus-infected adults in the United States. Archives of general psychiatry, 58, 721–728.PubMedCrossRef
Bolton, P. (2001). Cross-cultural validity and reliability testing of a standard psychiatric assessment instrument without a gold standard. Journal of Nervous and Mental Disease, 189, 238–242.PubMedCrossRef
Cunningham, W. E., Sohler, N. L., Tobias, C., Drainoni, M. L., Bradford, J., Davis, C., Cabral, H. J., Cunningham, C. O., Eldred, L., & Wong, M. D. (2006). Health services utilization for people with HIV infection: Comparison of a population targeted for outreach with the U.S. population in care. Medical Care, 44, 1038–1047.PubMedCrossRef
Fairfield, K. M., Libman, H., Davis, R. B., & Eisenberg, D. M. (1999). Delays in protease inhibitor use in clinical practice. Journal of General Internal Medicine, 14, 395–401.PubMedCrossRef
Fritz, K. E., Woelk, G. B., Bassett, M. T., McFarland, W. C., Routh, J. A., Tobaiwa O., & Stall, R. D. (2002). The association between alcohol use, sexual risk behavior and HIV infection among men attending beerhalls in Harare, Zimbabwe. AIDS and Behavior, 6, 221–228.CrossRef
Galvan, F. H., Bing, E. G., Fleishman, J. A., London, A. S., Caetano, R., Burnam, M. A., Longshore, D., Morton, S. C., Orlando, M., & Sharipo, M. (2002). The prevalence of alcohol consumption and heavy drinking among people with HIV in the United States: Results from the HIV cost and services utilization study. Journal of Studies on Alcohol, 63, 179–186.PubMed
Joyce, G. F., Chan, K. S., Orlando, M., & Burnam, M.A. (2005). Mental health status and use of general medical services for persons with human immunodeficiency virus. Medical Care, 43, 834–839.PubMedCrossRef
Kaaya, S. F., Fawzi, M. C., Mbwambo, J. K., Lee, B., Msamanga, G. I., & Fawzi, W. (2002). Validity of the Hopkins symptom checklist-25 amongst HIV-positive pregnant women in Tanzania. Acta Psychiatrica Scandinavica, 106, 9–19.PubMedCrossRef
Kaharuza, F. M., Bunnell, R., Moss, S., Purcell, D. W., Bikaako-Kajura, W., Wamai, N., Downing, R., Solberg, P., Coutinho, A., & Mermin, J. (2006). Depression and CD4 cell count among persons with HIV infection in Uganda. AIDS and Behavior, 10, S105–S111.PubMedCrossRef
Kalichman, S. C., Rompa, D., & Cage, M. (2000). Distinguishing between overlapping somatic symptoms of depression and HIV disease in people living with HIV-AIDS. Journal of Nervous and Mental Disease, 188, 662–670.PubMedCrossRef
Kalichman, S. C., Sikkema, K., & Somlai, A. (1995). Assessing persons with human immunodeficiency virus (HIV) infection using the Beck Depression Inventory: Disease processes and other potential confounds. Journal of Personality Assessment, 64, 86–100.PubMedCrossRef
Leserman, J. (2003). HIV disease progression: Depression, stress and possible mechanisms. Society of Biological Psychiatry, 54, 295–306.CrossRef
Loughlin, A., Metsch, L., Gardner, L., Anderson-Mahoney, P., Barrigan, M., & Strathdee, S. (2004). Provider barriers to prescribing HAART to medically-eligible HIV-infected drug users. AIDS Care, 16, 485–500.PubMedCrossRef
Lyketsos, C. G., Hutton, H., Fishman, M., Schwartz, J., & Treisman, G. J. (1996). Psychiatric morbidity on entry to an HIV primary care clinic. Journal of Acquired Immune Deficiency Syndromes, 10, 1033–1039.
Maisels, L., Steinberg, J., & Tobias, C. (2001). An investigation of why eligible patients do not receive HAART. AIDS Patient Care and STDS, 15, 185–191.PubMedCrossRef
Masson, C. L., Sorensen, J. L., Phibbs, C. S., & Okin, R. L. (2004). Predictors of medical service utilization among individuals with co-occurring HIV infection and substance abuse disorders. AIDS Care, 16, 744–755.PubMedCrossRef
Mbulaiteye, S. M., Ruberantwari, A., Nakiyingi, J. S., Carpenter, L. M., Kamali, A., & Whitworth, J. A. G. (2000). Alcohol and HIV: A study among sexually active adults in rural southwest Uganda. International Journal of Epidemiology, 29, 911–915.PubMedCrossRef
McKelvey, R. S., Mao, A. R., & Webb, J. A. (1993a). Premigratory expectations and mental health symptomatology in a group of Vietnamese Amerasian youth. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 414–418.PubMedCrossRef
McKelvey, R. S., Webb, J. A., & Mao, A. R. (1993b). Premigratory risk factors in Vietnamese Amerasians. American Journal of Psychiatry, 150, 470–473.PubMed
McNaghten, A. D., Hanson, D. L., Dworkin, M. S., Jones, J. L., & the Adult/Adolescent Spectrum of HIV Disease Group. (2003). Differences in prescription of ART in a large cohort of HIV-infected patients. Journal of Acquired Immune Deficiency Syndromes, 32, 499–505.
Ministry of Health, Republic of Uganda (2003). National antiretroviral treatment and care guidelines for adults and children. (1st ed.). Kampala, Uganda: Ministry of Health Republic of Uganda.
Mollica, R. F., Wyshak, G., de Marneffe, D., Khuon, F., & Lavelle, J. (1987). Indochinese version of the Hopkins Symptom Checklist-25: A screening instrument for psychiatric care of refugees. American Journal of Psychiatry, 144, 497–500.PubMed
Mouanoutoua, V. L., & Brown, L. G. (1995). Hopkins Symptom Checklist Hmong version: A screening instrument for psychological distress. Journal of Personality Assessment, 64, 376–383.PubMedCrossRef
Newman, C. E., Bonar, M., Greville, H. S., Thompson, S. C., Bessarab, D., & Kippax, S. C. (2007). Barriers and incentives to HIV treatment update among aboriginal people in Western Australia. Acquired Immune Deficiency Syndrome, 21, S13–S17.PubMed
Olley, B. O., Gxamza, F., Seedat, S., Theron, H., Taljaard, J., Reid, E., Reuter, H., & Stein, D. J. (2003). Psychopathology and coping in recently diagnosed HIV/AIDS patients—the role of gender. South African Medical Journal, 93, 928–931.PubMed
Saunders, J. B., Aasland, O. G., Babor, T. F., de la Fuente, J. R., & Grant, M. (1993). Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption—II. Addiction, 88, 791–804.PubMedCrossRef
Sebit, M. B., Chandiwana, S. K., Latif, A. S., Gomo, E., Acuda, S. W., Makoni, F., & Vushe, J. (2002). Neuropsychiatric aspects of HIV disease progression. Impact of traditional herbs on adult patients in Zimbabwe. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 26, 451–456.PubMedCrossRef
Sebit, M. B., Tombe, M., Siziya, S., Balus, S., Nkomo, S. D., & Maramba, P. (2003). Prevalence of HIV/AIDS and psychiatric disorders and their related risk factors among adults in Epworth, Zimbabwe. East African Medical Journal, 80, 503–512.PubMed
Shaffer, D. N., Njeri, R., Justice, A. C., Odero, W. W., & Tierney, W. M. (2004). Alcohol abuse among patients with and without HIV infection attending public clinics in western Kenya. East African Medical Journal, 81, 594–598.PubMed
Sullivan, L. E., Fiellin, D. A., & O’Connor, P. G. (2005). The prevalence and impact of alcohol problems in major depression: A systematic review. American Journal of Medicine, 118, 330–341.PubMedCrossRef
Tucker, J. S., Burnam, A., Sherbourne, C. D., Kung, F. Y., & Gifford, A. L. (2003). Substance use and mental health correlates of nonadherence to antiretroviral medications in a sample of patients with human immunodeficiency virus infection. American Journal of Medicine, 114, 573–580.PubMedCrossRef
Wells, K. B., Stewart, A., Hays, R. D., Burnam, M. A., Rogers, W., Daniels, M., Berry, S., Greenfield, S., & Ware, J. (1989). The functioning and well-being of depressed patients. Results from the medical outcomes study. Journal of the American Medical Association, 262, 914–919.PubMedCrossRef
Metadata
Title
Alcohol Use, Depressive Symptoms and the Receipt of Antiretroviral Therapy in Southwest Uganda
Authors
Priscilla Martinez
Irene Andia
Nneka Emenyonu
Judith A. Hahn
Edvard Hauff
Larry Pepper
David R. Bangsberg
Publication date
01-07-2008
Publisher
Springer US
Published in
AIDS and Behavior / Issue 4/2008
Print ISSN: 1090-7165
Electronic ISSN: 1573-3254
DOI
https://doi.org/10.1007/s10461-007-9312-x

Other articles of this Issue 4/2008

AIDS and Behavior 4/2008 Go to the issue

Original Paper

Sexual Difficulties in People Living with HIV in France—Results from a Large Representative Sample of Outpatients Attending French Hospitals (ANRS-EN12-VESPA)

Original Paper

Implications of Cannabis Use and Heavy Alcohol Use on HIV Drug Risk Behaviors in Russian Heroin Users

Substantive Review

Effects of HIV-Prevention Interventions for Samples with Higher and Lower Percents of Latinos and Latin Americans: A Meta-Analysis of Change in Condom Use and Knowledge

Original Paper

High Levels of Risk Behavior Among People Living with HIV Initiating and Waiting to Start Antiretroviral Therapy in Cape Town South Africa

Original Paper

Risk Behaviors of Homeless Men in India: A Potential Bridge Population for HIV Infection

Original Paper

Stimulant Injectors in Ukraine: The Next Wave of the Epidemic?
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits