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Published in: Journal of Medical Case Reports 1/2024

Open Access 01-12-2024 | Albendazole | Case report

Primary seronegative intermuscular hydatidosis in a child, an infection that should be approached like a tumor: a case report and review of the literature

Authors: Reza Tavakoli Darestani, Gholamhossein Kazemian, Sina Afzal, Mojtaba Baroutkoub, Mahdi Aghaalikhani, Farzad Amouzadeh Omrani

Published in: Journal of Medical Case Reports | Issue 1/2024

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Abstract

Introduction

Intermuscular hydatid cyst is one of the rarest types of hydatid cyst, and as far as we know, only nine cases were reported in the literature before this study.

Case presentation

We present a 10-year-old Iranian child with an intermuscular cystic mass in the medial-distal thigh. Despite the typical imaging findings, the patient's serological and hematological tests were negative for hydatid cyst. The cyst underwent wide excision accompanied by neoadjuvant and adjuvant chemotherapy with Albendazole. No evidence of recurrence was detected during the one-year follow-up.

Conclusion

Hydatid cysts should always be considered in the differential diagnosis of soft tissue cystic masses in endemic areas, and aspiration or drainage should be avoided as much as possible, even when serological tests are negative and imaging is non-diagnostic. In cases where the diagnosis of a hydatid cyst has been confirmed before the surgery, it is recommended to approach the cyst, like a tumor with chemotherapy using Albendazole both before and after wide cyst excision.
Literature
1.
go back to reference Niraula BB, Regmi A, Bansal S, Dhingra M, Phulware RH, Bhagat SK. Hydatid disease of tibia reconstructed with allograft: a rare case report and literature review. J West Afr College Surg. 2023;13(2):122.CrossRef Niraula BB, Regmi A, Bansal S, Dhingra M, Phulware RH, Bhagat SK. Hydatid disease of tibia reconstructed with allograft: a rare case report and literature review. J West Afr College Surg. 2023;13(2):122.CrossRef
2.
go back to reference Sadjjadi SM. Present situation of echinococcosis in the Middle East and Arabic North Africa. Parasitol Int. 2006;55:S197–202.CrossRefPubMed Sadjjadi SM. Present situation of echinococcosis in the Middle East and Arabic North Africa. Parasitol Int. 2006;55:S197–202.CrossRefPubMed
3.
4.
go back to reference Garcia-Diez A, Ros Mendoza L, Villacampa V, Cozar M, Fuertes M. MRI evaluation of soft tissue hydatid disease. Eur Radiol. 2000;10:462–6.CrossRefPubMed Garcia-Diez A, Ros Mendoza L, Villacampa V, Cozar M, Fuertes M. MRI evaluation of soft tissue hydatid disease. Eur Radiol. 2000;10:462–6.CrossRefPubMed
5.
6.
go back to reference Cankorkmaz L, Ozturk H, Koyluoglu G, Atalar MH, Arslan MS. Intermuscular hydatid cyst in a 4-year-old child: a case report. J Pediatr Surg. 2007;42(11):1946–8.CrossRefPubMed Cankorkmaz L, Ozturk H, Koyluoglu G, Atalar MH, Arslan MS. Intermuscular hydatid cyst in a 4-year-old child: a case report. J Pediatr Surg. 2007;42(11):1946–8.CrossRefPubMed
7.
go back to reference Cevik M. Unusual primary hydatid cyst from soft tissue in children: four cases and review of literature. jurnalul pediatrului. 2012;15. Cevik M. Unusual primary hydatid cyst from soft tissue in children: four cases and review of literature. jurnalul pediatrului. 2012;15.
8.
go back to reference Andronikou S, Welman CJ, Kader E. Classic and unusual appearances of hydatid disease in children. Pediatr Radiol. 2002;32:817–28.CrossRefPubMed Andronikou S, Welman CJ, Kader E. Classic and unusual appearances of hydatid disease in children. Pediatr Radiol. 2002;32:817–28.CrossRefPubMed
9.
go back to reference Salamone G, Licari L, Randisi B, Falco N, Tutino R, Vaglica A, et al. Uncommon localizations of hydatid cyst. Review of the literature. II Giornale di chirurgia. 2016;37(4):180. Salamone G, Licari L, Randisi B, Falco N, Tutino R, Vaglica A, et al. Uncommon localizations of hydatid cyst. Review of the literature. II Giornale di chirurgia. 2016;37(4):180.
10.
go back to reference Rao SS, Mehra B, Narang R. The spectrum of hydatid disease in rural central India: an 11-year experience. Ann Trop Med Public Health. 2012;5(3):225.CrossRef Rao SS, Mehra B, Narang R. The spectrum of hydatid disease in rural central India: an 11-year experience. Ann Trop Med Public Health. 2012;5(3):225.CrossRef
11.
go back to reference Durhan G, Tan AA, Düzgün SA, Akkaya S, Arıyürek OM. Radiological manifestations of thoracic hydatid cysts: pulmonary and extrapulmonary findings. Insights Imaging. 2020;11:1–11.CrossRef Durhan G, Tan AA, Düzgün SA, Akkaya S, Arıyürek OM. Radiological manifestations of thoracic hydatid cysts: pulmonary and extrapulmonary findings. Insights Imaging. 2020;11:1–11.CrossRef
12.
go back to reference Khasawneh RA, Mohaidat ZM, Khasawneh RA, Zoghoul SB, Henawi YM. Unusual intramuscular locations as a first presentation of hydatid cyst disease in children: a report of two cases. BMC Pediatr. 2021;21(1):371.CrossRefPubMedPubMedCentral Khasawneh RA, Mohaidat ZM, Khasawneh RA, Zoghoul SB, Henawi YM. Unusual intramuscular locations as a first presentation of hydatid cyst disease in children: a report of two cases. BMC Pediatr. 2021;21(1):371.CrossRefPubMedPubMedCentral
13.
go back to reference Gougoulias N, Varitimidis S, Bargiotas K, Dovas T, Karydakis G, Dailiana Z. Skeletal muscle hydatid cysts presenting as soft tissue masses. Hippokratia. 2010;14(2):126.PubMedPubMedCentral Gougoulias N, Varitimidis S, Bargiotas K, Dovas T, Karydakis G, Dailiana Z. Skeletal muscle hydatid cysts presenting as soft tissue masses. Hippokratia. 2010;14(2):126.PubMedPubMedCentral
14.
go back to reference Balioglu MB, Gok M, Ozcan HE, Alpak O. An unusual cause of circulatory disorder due to a rare intermuscular hydatid cyst of cruris: a case report. Balioglu MB, Gok M, Ozcan HE, Alpak O. An unusual cause of circulatory disorder due to a rare intermuscular hydatid cyst of cruris: a case report.
15.
go back to reference Alimehmeti R, Seferi A, Rroji A, Alimehmeti M. Saphenous neuropathy due to large hydatid cyst within long adductor muscle: case report and literature review. J Infect Dev Ctries. 2012;6(06):531–5.CrossRefPubMed Alimehmeti R, Seferi A, Rroji A, Alimehmeti M. Saphenous neuropathy due to large hydatid cyst within long adductor muscle: case report and literature review. J Infect Dev Ctries. 2012;6(06):531–5.CrossRefPubMed
16.
go back to reference Tuna S, Duymus TM, Yanik HS, Durakbasa MO, Mutlu S, Erdem S. Hydatid cyst of biceps brachii associated with peripheral neuropathy. Int J Surg Case Rep. 2015;8:150–3.CrossRefPubMedCentral Tuna S, Duymus TM, Yanik HS, Durakbasa MO, Mutlu S, Erdem S. Hydatid cyst of biceps brachii associated with peripheral neuropathy. Int J Surg Case Rep. 2015;8:150–3.CrossRefPubMedCentral
18.
go back to reference Hamdi M, Touati B, Abid A. Primary hydatid cyst of the biceps femoris. Musculoskelet Surg. 2010;94:59–61.CrossRefPubMed Hamdi M, Touati B, Abid A. Primary hydatid cyst of the biceps femoris. Musculoskelet Surg. 2010;94:59–61.CrossRefPubMed
19.
go back to reference Zalaquett E, Menias C, Garrido F, Vargas M, Olivares JF, Campos D, et al. Imaging of hydatid disease with a focus on extrahepatic involvement. Radiographics. 2017;37(3):901–23.CrossRefPubMed Zalaquett E, Menias C, Garrido F, Vargas M, Olivares JF, Campos D, et al. Imaging of hydatid disease with a focus on extrahepatic involvement. Radiographics. 2017;37(3):901–23.CrossRefPubMed
20.
go back to reference Kayaalp C, Dirican A, Aydin C. Primary subcutaneous hydatid cysts: a review of 22 cases. Int J Surg. 2011;9(2):117–21.CrossRefPubMed Kayaalp C, Dirican A, Aydin C. Primary subcutaneous hydatid cysts: a review of 22 cases. Int J Surg. 2011;9(2):117–21.CrossRefPubMed
21.
go back to reference García-Alvarez F, Torcal J, Salinas JC, Navarro A, García-Alvarez I, Navarro-Zorraquino M, et al. Musculoskeletal hydatid disease: a report of 13 cases. Acta Orthop Scand. 2002;73(2):227–31.CrossRefPubMed García-Alvarez F, Torcal J, Salinas JC, Navarro A, García-Alvarez I, Navarro-Zorraquino M, et al. Musculoskeletal hydatid disease: a report of 13 cases. Acta Orthop Scand. 2002;73(2):227–31.CrossRefPubMed
22.
go back to reference Katılmış H, Öztürkcan S, Özdemir İ, Güvenç İA, Özturan Ş. Primary hydatid cyst of the neck. Am J Otolaryngol. 2007;28(3):205–7.CrossRefPubMed Katılmış H, Öztürkcan S, Özdemir İ, Güvenç İA, Özturan Ş. Primary hydatid cyst of the neck. Am J Otolaryngol. 2007;28(3):205–7.CrossRefPubMed
23.
24.
go back to reference Dalal AK, Dalal UR, Vardhan JV, Dhawan S, Dahiya H. A rare case of large hydatid cyst at atypical location: case study. Asian J Case Rep Surg. 2021;8(1):23–6. Dalal AK, Dalal UR, Vardhan JV, Dhawan S, Dahiya H. A rare case of large hydatid cyst at atypical location: case study. Asian J Case Rep Surg. 2021;8(1):23–6.
25.
go back to reference Arif SH, Wani NA, Zargar SA, Wani MA, Tabassum R, Hussain Z, et al. Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver. Int J Surg. 2008;6(6):448–51.CrossRefPubMed Arif SH, Wani NA, Zargar SA, Wani MA, Tabassum R, Hussain Z, et al. Albendazole as an adjuvant to the standard surgical management of hydatid cyst liver. Int J Surg. 2008;6(6):448–51.CrossRefPubMed
26.
27.
go back to reference Aktan A, Yalin R. Preoperative albendazole treatment for liver hydatid disease decreases the viability of the cyst. Eur J Gastroenterol Hepatol. 1996;8(9):877–9.PubMed Aktan A, Yalin R. Preoperative albendazole treatment for liver hydatid disease decreases the viability of the cyst. Eur J Gastroenterol Hepatol. 1996;8(9):877–9.PubMed
28.
go back to reference Bayram M, Sirikci A. Hydatic cyst located intermuscular area of the forearm: MR imaging findings. Eur J Radiol. 2000;36(3):130–2.CrossRefPubMed Bayram M, Sirikci A. Hydatic cyst located intermuscular area of the forearm: MR imaging findings. Eur J Radiol. 2000;36(3):130–2.CrossRefPubMed
29.
go back to reference Mortazavi SJ, Motamedi M, Asadollahi S, Haeri H, Moghtadaee M. Primary intermuscular hydatid cyst of the thigh. Orthopedics (Online). 2008;31(1):85.CrossRef Mortazavi SJ, Motamedi M, Asadollahi S, Haeri H, Moghtadaee M. Primary intermuscular hydatid cyst of the thigh. Orthopedics (Online). 2008;31(1):85.CrossRef
30.
go back to reference Abumunaser L. Primary intermuscular hydatid cyst of the posterior thigh: a rare presentation. Egypt Orthop J. 2017;52(4):333.CrossRef Abumunaser L. Primary intermuscular hydatid cyst of the posterior thigh: a rare presentation. Egypt Orthop J. 2017;52(4):333.CrossRef
31.
go back to reference Talal G, Saudi F, Ouazzani N, Fekhaoui M, Boufetal M, Reda-Allah B. Intermuscular hydatid cyst isolated from the arm. Talal G, Saudi F, Ouazzani N, Fekhaoui M, Boufetal M, Reda-Allah B. Intermuscular hydatid cyst isolated from the arm.
32.
go back to reference Malik A, Nabi N, Bari A. Recurrent primary intermuscular hydatid cyst of thigh-a case report. J Otolaryngol ENT Res. 2018;10(6):382–3.CrossRef Malik A, Nabi N, Bari A. Recurrent primary intermuscular hydatid cyst of thigh-a case report. J Otolaryngol ENT Res. 2018;10(6):382–3.CrossRef
33.
go back to reference Meena SP, Raj R, Puranik A, Kompally PV. Primary echinococcal cyst in Trapezius muscle: an unusual intermuscular hydatidosis and review of literature. J Family Med Prim Care. 2020;9(9):5055.CrossRefPubMedPubMedCentral Meena SP, Raj R, Puranik A, Kompally PV. Primary echinococcal cyst in Trapezius muscle: an unusual intermuscular hydatidosis and review of literature. J Family Med Prim Care. 2020;9(9):5055.CrossRefPubMedPubMedCentral
34.
go back to reference Karakol P, Tatar BE. Unexpected location of hydatid cyst. Ann Med Res. 2021;28:608.CrossRef Karakol P, Tatar BE. Unexpected location of hydatid cyst. Ann Med Res. 2021;28:608.CrossRef
Metadata
Title
Primary seronegative intermuscular hydatidosis in a child, an infection that should be approached like a tumor: a case report and review of the literature
Authors
Reza Tavakoli Darestani
Gholamhossein Kazemian
Sina Afzal
Mojtaba Baroutkoub
Mahdi Aghaalikhani
Farzad Amouzadeh Omrani
Publication date
01-12-2024
Publisher
BioMed Central
Keyword
Albendazole
Published in
Journal of Medical Case Reports / Issue 1/2024
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-024-04405-6

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