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Published in: Current Allergy and Asthma Reports 8/2016

01-08-2016 | Asthma (WJ Calhoun and V Ortega, Section Editors)

Airway Microbiota and the Implications of Dysbiosis in Asthma

Authors: Juliana Durack, Homer A. Boushey, Susan V. Lynch

Published in: Current Allergy and Asthma Reports | Issue 8/2016

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Abstract

The mucosal surfaces of the human body are typically colonized by polymicrobial communities seeded in infancy and are continuously shaped by environmental exposures. These communities interact with the mucosal immune system to maintain homeostasis in health, but perturbations in their composition and function are associated with lower airway diseases, including asthma, a developmental and heterogeneous chronic disease with various degrees and types of airway inflammation. This review will summarize recent studies examining airway microbiota dysbioses associated with asthma and their relationship with the pathophysiology of this disease.
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Metadata
Title
Airway Microbiota and the Implications of Dysbiosis in Asthma
Authors
Juliana Durack
Homer A. Boushey
Susan V. Lynch
Publication date
01-08-2016
Publisher
Springer US
Published in
Current Allergy and Asthma Reports / Issue 8/2016
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-016-0631-8

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