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Heart Failure Reviews

13-04-2024 | Affective Disorder

Comparative analysis of treatment options for chronic heart failure and depression: a systematic review and Bayesian network meta-analysis

Authors: Hamidreza Soleimani, Ali Nasrollahizadeh, Mohsen Hajiqasemi, Mandana Ebrahimzade, Homa Taheri, Pouya Ebrahimi, Haleh Ashraf, Marc D. Samsky, Kaveh Hosseini

Published in: Heart Failure Reviews

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Abstract

Different interventions have been evaluated for the treatment of depression in heart failure (HF) patients. However, clear and established recommendations are lacking. PubMed, Scopus, and Web of Science databases were systematically searched for randomized controlled trials (RCT) evaluating the effect of various treatment options on depression scores in heart failure patients. The primary outcome was a change in depression scores presented as standardized mean difference (SMD). A Bayesian network for meta-analysis was constructed. Twenty-five RCTs were included, randomizing 6014 patients with confirmed heart failure and depression between 2003 and 2022. Compared to treatment as usual (TAU), only cognitive behavioral therapy (CBT) (SMD − 0.60, CI95% [− 1.0, − 0.17]) leads to a significant reduction in depression scores. Other interventions did not improve depression scores significantly. Our results show that for patients with HF and depression, CBT can significantly improve measures of depression, being the most efficacious treatment.
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Metadata
Title
Comparative analysis of treatment options for chronic heart failure and depression: a systematic review and Bayesian network meta-analysis
Authors
Hamidreza Soleimani
Ali Nasrollahizadeh
Mohsen Hajiqasemi
Mandana Ebrahimzade
Homa Taheri
Pouya Ebrahimi
Haleh Ashraf
Marc D. Samsky
Kaveh Hosseini
Publication date
13-04-2024
Publisher
Springer US
Published in
Heart Failure Reviews
Print ISSN: 1382-4147
Electronic ISSN: 1573-7322
DOI
https://doi.org/10.1007/s10741-024-10403-z

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