Published in:
01-01-2010 | Commentary
Adverse Drug Interactions
Moving from Perception to Action
Authors:
Ryan Mayhew, June M. McKoy, Thanh Ha Luu, Isaac Lopez, Melissa Frick, Dr Charles L. Bennett
Published in:
PharmacoEconomics
|
Issue 1/2010
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Excerpt
The use of highly active antiretroviral therapy (HAART) has been exceptionally effective in improving the mortality and quality of life of patients with HIV/AIDS. Patients who are receiving HAART develop less resistance to individual drugs and typically experience less toxicity than those receiving single-agent therapy. Since HIV/AIDS was first discovered in 1981, 32 agents have been approved by the US FDA, including 26 individual agents and six combinations.[
1] However, drug-drug interactions remain a significant concern as new therapeutic agents and classes emerge and fresh combinations of established regimens are explored. …