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Current Osteoporosis Reports
Published in: Current Osteoporosis Reports 3/2016

01-06-2016 | Regenerative Biology and Medicine in Osteoporosis (T Webster, Section Editor)

Advances in Nanotechnology for the Treatment of Osteoporosis

Authors: Mikayla Barry, Hannah Pearce, Lauren Cross, Marco Tatullo, Akhilesh K. Gaharwar

Published in: Current Osteoporosis Reports | Issue 3/2016

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Abstract

Osteoporosis is a degenerative bone disease commonly related to aging. With an increase in life expectancies worldwide, the prevalence of the disease is expected to rise. Current clinical therapeutic treatments are not able to offer long-term solutions to counter the bone mass loss and the increased risk of fractures, which are the primary characteristics of the disease. However, the combination of bioactive nanomaterials within a biomaterial scaffold shows promise for the development of a localized, long-term treatment for those affected by osteoporosis. This review summarizes the unique characteristics of engineered nanoparticles that render them applicable for bone regeneration and recaps the current body of knowledge on nanomaterials with potential for osteoporosis treatment and bone regeneration. Specifically, we highlight new developments that are shaping this emerging field and evaluate applications of recently developed nanomaterials for osteoporosis treatment. Finally, we will identify promising new research directions in nanotechnology for bone regeneration.
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Metadata
Title
Advances in Nanotechnology for the Treatment of Osteoporosis
Authors
Mikayla Barry
Hannah Pearce
Lauren Cross
Marco Tatullo
Akhilesh K. Gaharwar
Publication date
01-06-2016
Publisher
Springer US
Published in
Current Osteoporosis Reports / Issue 3/2016
Print ISSN: 1544-1873
Electronic ISSN: 1544-2241
DOI
https://doi.org/10.1007/s11914-016-0306-3

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