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Diabetologia
Published in: Diabetologia 8/2012

01-08-2012 | Letter

ADVANCE and glycaemia thresholds: a need to clarify the statistical approach. Reply to Currie CJ [letter]

Authors: S. Zoungas, J. Chalmers, Q. Li, M. Woodward

Published in: Diabetologia | Issue 8/2012

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Excerpt

To the Editor: We thank Professor Currie for his interesting interpretation [1] of the complex analyses undertaken to examine the relationship between HbA1c and outcomes in the ADVANCE trial cohort [2]. …
Literature
1.
2.
Zoungas S, Chalmers J, Ninomiya T et al (2012) Association of HbA1c levels with vascular complications and death in patients with type 2 diabetes: evidence of glycaemic thresholds. Diabetologia 55:636–643PubMedCrossRef
3.
ADVANCE Collaborative Group, Patel A, MacMahon S et al (2008) Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 358:2560–2572PubMedCrossRef
4.
Riddle MC, Ambrosius WT, Brillon DJ et al (2010) Epidemiologic relationships between A1C and all-cause mortality during a median 3.4-year follow-up of glycemic treatment in the ACCORD trial. Diabetes Care 33:983–990PubMedCrossRef
Metadata
Title
ADVANCE and glycaemia thresholds: a need to clarify the statistical approach. Reply to Currie CJ [letter]
Authors
S. Zoungas
J. Chalmers
Q. Li
M. Woodward
Publication date
01-08-2012
Publisher
Springer-Verlag
Published in
Diabetologia / Issue 8/2012
Print ISSN: 0012-186X
Electronic ISSN: 1432-0428
DOI
https://doi.org/10.1007/s00125-012-2576-3

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At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

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