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European Radiology

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01-10-2010 | Emergency Radiology

Adrenal gland volume measurement in septic shock and control patients: a pilot study

Authors: Stephanie Nougaret, B. Jung, S. Aufort, G. Chanques, S. Jaber, B. Gallix

Published in: European Radiology | Issue 10/2010

Abstract

Objectives:

To compare adrenal gland volume in septic shock patients and control patients by using semi-automated volumetry.

Methods:

Adrenal gland volume and its inter-observer variability were measured with tomodensitometry using semi-automated software in 104 septic shock patients and in 40 control patients. The volumes of control and septic shock patients were compared and the relationship between volume and outcome in intensive care was studied.

Results:

The mean total volume of both adrenal glands was 7.2 ± 2.0 cm³ in control subjects and 13.3 ± 4.7 cm³ for total adrenal gland volume in septic shock patients (p < 0.0001). Measurement reproducibility was excellent with a concordance correlation coefficient value of 0.87. The increasing adrenal gland volume was associated with a higher rate of survival in intensive care.

Conclusion:

The present study reports that with semi-automated software, adrenal gland volume can be measured easily and reproducibly. Adrenal gland volume was found to be nearly double in sepsis compared with control patients. The absence of increased volume during sepsis would appear to be associated with a higher rate of mortality and may represent a prognosis factor which may help the clinician to guide their strategy.

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Title: Adrenal gland volume measurement in septic shock and control patients: a pilot study
Authors: Stephanie Nougaret
B. Jung
S. Aufort
G. Chanques
S. Jaber
B. Gallix
Publication date: 01-10-2010
Publisher: Springer-Verlag
Published in: European Radiology / Issue 10/2010
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-010-1804-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Adrenal gland volume measurement in septic shock and control patients: a pilot study

Abstract

Objectives:

Methods:

Results:

Conclusion:

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives:

Methods:

Results:

Conclusion:

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