Published in:
Open Access
01-12-2012 | Poster presentation
Adrenal function in rheumatoid arthritis: a correlation with disease activity
Authors:
Richard Imrich, Miroslav Vlcek, Jana Kerlik, Michael Vogeser, Fabian Kirchhoff, Adela Penesova, Zofia Radikova, Jozef Lukac, Jozef Rovensky
Published in:
Arthritis Research & Therapy
|
Special Issue 1/2012
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Excerpt
Hypothalamic-pituitary-adrenocortical dysfunction contributes to a complex pathogenesis of rheumatoid arthritis (RA). Decreased production of adrenal androgens and subtle changes in cortisol production has been observed in RA, particularly in female patients with premenopausal onset of the disease. Our study was aimed to investigate (1) adrenocortical function in relation to disease and inflammatory activity and to analyze cortisol bioavailability in RA females. …