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Virology Journal
Published in: Virology Journal 1/2023

Open Access 01-12-2023 | Adenovirus | Case Report

Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma

Authors: Amary Fall, Victoria L. Campodónico, Craig Howard, Nicholas Gallagher, Gabrielle Bailey, Adriana E. Kajon, Heba H. Mostafa

Published in: Virology Journal | Issue 1/2023

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Abstract

Adenovirus (HAdV) F41 is a common cause of gastroenteritis and has rarely been reported associated with disseminated disease. In this report, an adult patient with a history of ulcerative colitis, cryptogenic cirrhosis, stage III adenocarcinoma, high-grade diffuse large B-cell lymphoma on chemotherapy was diagnosed with disseminated adenovirus infection. HAdV DNA was quantified in stool, plasma, and urine with viral loads of 7, 4, and 3 log10 copies/mL, respectively. The patient’s course was rapidly progressive and he passed away 2 days after initiation of antiviral therapy. The patient’s infecting virus was characterized as HAdV-F41 by whole genome sequencing.
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Metadata
Title
Dissemination and genome characterization of a human adenovirus F41 in a patient with B-Cell lymphoma
Authors
Amary Fall
Victoria L. Campodónico
Craig Howard
Nicholas Gallagher
Gabrielle Bailey
Adriana E. Kajon
Heba H. Mostafa
Publication date
01-12-2023
Publisher
BioMed Central
Published in
Virology Journal / Issue 1/2023
Electronic ISSN: 1743-422X
DOI
https://doi.org/10.1186/s12985-023-02101-3

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