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Published in: Infection 1/2021

01-02-2021 | Adenovirus | Brief Report

Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings

Authors: Jens T. Van Praet, Ann-Sofie Coene, Kris Van De Moortele, Patrick Descheemaeker, Marijke Reynders

Published in: Infection | Issue 1/2021

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Abstract

A subset of patients with Covid-19 presents with negative RT-PCR screening but suspect CT findings. Using four commercially available anti-SARS-CoV-2 IgG immuno-assays, we found this subset constituted 9.2% of all consecutively admitted outpatients with Covid-19 in our hospital. Clinical specificity for Covid-19 of some N protein-based immuno-assays was suboptimal, as positive results were observed in control patients with recent common human coronavirus, influenza B and adenovirus infections.
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Metadata
Title
Comparison of four commercial SARS-CoV-2 IgG immuno-assays in RT-PCR negative patients with suspect CT findings
Authors
Jens T. Van Praet
Ann-Sofie Coene
Kris Van De Moortele
Patrick Descheemaeker
Marijke Reynders
Publication date
01-02-2021
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 1/2021
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-020-01523-3

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