Adenocarcinoma Ex-goblet Cell Carcinoid of the Appendix: a Case Report and Overview of the Disease

Excerpt

Goblet cell carcinoid (GCC) of the appendix is a rare disease with varying guidelines for histopathologic diagnosis and management. The disease is intriguing in terms of its pathologic features. Three subtypes have been described depending on the presence of signet ring cells and extent of differentiation of the adenocarcinoma component [1]. The clinical behavior of the tumor ranges from aggressive to relatively indolent disease. Treatment is based on extent of the disease, grade of the tumor, and individual patient characteristics. Whereas surgical resection remains the mainstay of resectable disease, adjuvant chemotherapy and intraperitoneal chemotherapy have been employed. We discuss our experience with diagnosis and management of the disease in a patient we encountered. …