T-cell acute lymphoblastic leukemia with atypical intracytoplasmic inclusions in the blasts

In this study, we investigate the utility of flow cytometry as a diagnostic tool for identifying T-cell acute lymphoblastic leukemia (T-ALL). Traditional hematopathological examination has limitations, prompting the need for more accurate diagnostic methods. We focus on markers such as CD7, Cy CD3, CD5, CD13, CD38, CD117, and CD45, which have been chosen due to their ability to detect altered expressions and changes that can be observed microscopically. Our findings reveal the presence of atypical intracytoplasmic inclusions in the blasts, which exhibit expressions of CD7, Cy CD3, CD5, CD13, CD38, CD117, and CD45. These markers demonstrate altered expression patterns that are indicative of T-ALL. This study highlights the diagnostic potential of flow cytometry in identifying T-ALL, allowing for a more comprehensive evaluation of diagnostic characteristics. The study demonstrates that flow cytometry can significantly enhance the diagnosis of T-ALL by offering a more accurate and efficient alternative to traditional hematopathological examination. Simultaneous evaluation of a wide range of diagnostic characteristics is made possible by this method, thereby improving our ability to detect and differentiate T-cell disorders like T-ALL. CD7, Cy CD3, CD5, CD13, CD38, CD117, and CD45 are identified as reliable indicators for T-ALL diagnosis due to their characteristic altered expression patterns.