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01-08-2020 | Acute Liver Failure | Letter to the Editor

Author’s reply: acute serologic autoimmune hepatitis in the post-partum period

Authors: Noriyuki Akutsu, Keisuke Ishigami, Hiroshi Nakase

Published in: Clinical Journal of Gastroenterology | Issue 4/2020

Excerpt

We appreciate Efe et al. s’ interest in our case and read your case with great interest. Since the first description of autoimmune hepatitis (AIH) by Waldenstörm in the early 1950s [1], AIH was considered to be a chronic liver disease of unknown etiology with variable patterns of presentation. Over the last decades, AIH can occur as acute onset hepatitis or fulminant hepatic failure [2]. In 20–30% of cases, AIH causes jaundice and a subset of these patients go on to acute liver failure (ALF) or fulminant failure. This pattern has not been extensively described in the medical literature and represents a challenge for physicians. …

Waldenstrom J. Leber. Blutproteine und Nahrungseiweiss. Dtsch Ges Verdau Stoffwechselkr. 1950;15:113–9.

Verma S, Maheshwari A, Thuluvath P. Liver failure as initial presentation of autoimmune hepatitis: clinical characteristics, predictors of response to steroid therapy, and outcomes. Hepatology. 2009;49:1396–7.CrossRef

Strettell MD, Donaldson PT, Thomson LJ, et al. Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis. Gastroenterology. 1997;112:2028–35.CrossRef

Buechter M, Manka P, Heinemann FM, et al. Potential triggering factors of acute liver failure as a first manifestation of autoimmune hepatitis-a single center experience of 52 adult patients. World J Gastroenterol. 2018;24:1410–8.CrossRef

Title: Author’s reply: acute serologic autoimmune hepatitis in the post-partum period
Authors: Noriyuki Akutsu
Keisuke Ishigami
Hiroshi Nakase
Publication date: 01-08-2020
Publisher: Springer Singapore
Keywords: Acute Liver Failure
Autoimmune Hepatitis
Published in: Clinical Journal of Gastroenterology / Issue 4/2020
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI: https://doi.org/10.1007/s12328-020-01120-9

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