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Intensive Care Medicine

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01-09-2020 | Acute Kidney Injury | Letter

Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study

Authors: Benoit Painvin, Pauline Guillot, Marie-Clémence Verdier, Arnaud Gacouin, Adel Maamar

Published in: Intensive Care Medicine | Issue 9/2020

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Al-Rawi H, Meggitt SJ, Williams FM, Wahie S (2018) Steady-state pharmacokinetics of hydroxychloroquine in patients with cutaneous lupus erythematosus. Lupus 27:847–852. https://doi.org/10.1177/0961203317727601CrossRefPubMed

Perinel S, Launay M, Botelho-Nevers É et al (2020) Towards optimization of hydroxychloroquine dosing in intensive care unit COVID-19 patients. Clin Infect Dis Off Publ Infect Dis Soc Am. https://doi.org/10.1093/cid/ciaa394CrossRef

Garcia-Cremades M, Solans BP, Hughes E et al (2020) Optimizing hydroxychloroquine dosing for patients with COVID-19: an integrative modeling approach for effective drug repurposing. Clin Pharmacol Ther. https://doi.org/10.1002/cpt.1856CrossRefPubMedPubMedCentral

Durcan L, Clarke WA, Magder LS, Petri M (2015) Hydroxychloroquine blood levels in systemic lupus erythematosus: clarifying dosing controversies and improving adherence. J Rheumatol 42:2092–2097. https://doi.org/10.3899/jrheum.150379CrossRefPubMedPubMedCentral

Yao X, Ye F, Zhang M et al (2020) In vitro antiviral activity and projection of optimized dosing design of hydroxychloroquine for the treatment of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clin Infect Dis Off Publ Infect Dis Soc Am. https://doi.org/10.1093/cid/ciaa237CrossRef

Title: Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study
Authors: Benoit Painvin
Pauline Guillot
Marie-Clémence Verdier
Arnaud Gacouin
Adel Maamar
Publication date: 01-09-2020
Publisher: Springer Berlin Heidelberg
Keywords: Acute Kidney Injury
Pharmacokinetics
COVID-19
Acute Kidney Injury
Hydroxychloroquine
Published in: Intensive Care Medicine / Issue 9/2020
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-020-06142-y

At a glance: The STEP trials

Springer Medicine

Hydroxychloroquine pharmacokinetic in COVID-19 critically ill patients: an observational cohort study

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At a glance: The STEP trials

Springer Medicine

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