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Published in: Clinical Journal of Gastroenterology 6/2016

01-12-2016 | Case Report

Acute exacerbation of irritable bowel syndrome prevented by prn oral triptan

Authors: Benjamin N. R. Cheyette, Sarah N. R. Cheyette

Published in: Clinical Journal of Gastroenterology | Issue 6/2016

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Abstract

We report a case of irritable bowel syndrome (IBS), diarrhea subtype, characterized by daily ‘morning rush’ and episodic acute exacerbations brought on by common IBS trigger foods including insoluble fiber, red wine and large/rich meals. The patient also had a history of migraine headaches, and a family history suggesting a common diathesis for both disorders. Given hypothesized contributions to IBS from dysregulation of the enteric serotonergic system, a trial of low-dose triptan medication was implemented in the context of the patient’s known IBS triggers, with highly satisfactory results.
Literature
1.
go back to reference Hungin AP, Chang L, Locke GR, Dennis EH, Barghout V. Irritable bowel syndrome in the United States: prevalence, symptom patterns and impact. Aliment Pharmacol Ther. 2005;21:1365–75.CrossRefPubMed Hungin AP, Chang L, Locke GR, Dennis EH, Barghout V. Irritable bowel syndrome in the United States: prevalence, symptom patterns and impact. Aliment Pharmacol Ther. 2005;21:1365–75.CrossRefPubMed
2.
go back to reference Mearin F, Lacy BE, Chang L, et al. Bowel disorders. Gastroenterology. 2016;150(6):1393–407.CrossRef Mearin F, Lacy BE, Chang L, et al. Bowel disorders. Gastroenterology. 2016;150(6):1393–407.CrossRef
4.
go back to reference Tack J, Vanuytsel T, Corsetti M. Modern management of irritable bowel syndrome: more than motility. Dig Dis. 2016;34:566–73.CrossRefPubMed Tack J, Vanuytsel T, Corsetti M. Modern management of irritable bowel syndrome: more than motility. Dig Dis. 2016;34:566–73.CrossRefPubMed
5.
go back to reference Shah SL, Lacy BE. Dietary interventions and irritable bowel syndrome: a review of the evidence. Curr Gastroenterol Rep. 2016;18:41.CrossRefPubMed Shah SL, Lacy BE. Dietary interventions and irritable bowel syndrome: a review of the evidence. Curr Gastroenterol Rep. 2016;18:41.CrossRefPubMed
6.
go back to reference McKenzie YA, Bowyer RK, Leach H, et al. British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet. 2016;29(5):549–75.CrossRefPubMed McKenzie YA, Bowyer RK, Leach H, et al. British Dietetic Association systematic review and evidence-based practice guidelines for the dietary management of irritable bowel syndrome in adults (2016 update). J Hum Nutr Diet. 2016;29(5):549–75.CrossRefPubMed
7.
go back to reference Staudacher HM, Irving PM, Lomer MC, Whelan K. Mechanisms and efficacy of dietary FODMAP restriction in IBS. Nat Rev Gastroenterol Hepatol. 2014;11:256–66.CrossRefPubMed Staudacher HM, Irving PM, Lomer MC, Whelan K. Mechanisms and efficacy of dietary FODMAP restriction in IBS. Nat Rev Gastroenterol Hepatol. 2014;11:256–66.CrossRefPubMed
8.
go back to reference Molina-Infante J, Serra J, Fernandez-Banares F, Mearin F. The low-FODMAP diet for irritable bowel syndrome: lights and shadows. Gastroenterol Hepatol. 2016;39:55–65.CrossRefPubMed Molina-Infante J, Serra J, Fernandez-Banares F, Mearin F. The low-FODMAP diet for irritable bowel syndrome: lights and shadows. Gastroenterol Hepatol. 2016;39:55–65.CrossRefPubMed
9.
go back to reference Farzaei MH, Bahramsoltani R, Abdollahi M, Rahimi R. The role of visceral hypersensitivity in irritable bowel syndrome: pharmacological targets and novel treatments. J Neurogastroenterol Motil 2016. doi:10.5056/jnm16001.PubMedPubMedCentral Farzaei MH, Bahramsoltani R, Abdollahi M, Rahimi R. The role of visceral hypersensitivity in irritable bowel syndrome: pharmacological targets and novel treatments. J Neurogastroenterol Motil 2016. doi:10.​5056/​jnm16001.PubMedPubMedCentral
10.
go back to reference Sikander A, Rana SV, Prasad KK. Role of serotonin in gastrointestinal motility and irritable bowel syndrome. Clin Chim Acta. 2009;403:47–55.CrossRefPubMed Sikander A, Rana SV, Prasad KK. Role of serotonin in gastrointestinal motility and irritable bowel syndrome. Clin Chim Acta. 2009;403:47–55.CrossRefPubMed
11.
go back to reference Garvin B, Wiley JW. The role of serotonin in irritable bowel syndrome: implications for management. Curr Gastroenterol Rep. 2008;10:363–8.CrossRefPubMed Garvin B, Wiley JW. The role of serotonin in irritable bowel syndrome: implications for management. Curr Gastroenterol Rep. 2008;10:363–8.CrossRefPubMed
12.
go back to reference Corsetti M, Whorwell P. Novel pharmacological therapies for irritable bowel syndrome. Expert Rev Gastroenterol Hepatol. 2016;10:807–15.CrossRefPubMed Corsetti M, Whorwell P. Novel pharmacological therapies for irritable bowel syndrome. Expert Rev Gastroenterol Hepatol. 2016;10:807–15.CrossRefPubMed
13.
go back to reference Bundeff AW, Woodis CB. Selective serotonin reuptake inhibitors for the treatment of irritable bowel syndrome. Ann Pharmacother. 2014;48:777–84.CrossRefPubMed Bundeff AW, Woodis CB. Selective serotonin reuptake inhibitors for the treatment of irritable bowel syndrome. Ann Pharmacother. 2014;48:777–84.CrossRefPubMed
14.
go back to reference Tepper SJ, Rapoport AM, Sheftell FD. Mechanisms of action of the 5-HT1B/1D receptor agonists. Arch Neurol. 2002;59:1084–8.CrossRefPubMed Tepper SJ, Rapoport AM, Sheftell FD. Mechanisms of action of the 5-HT1B/1D receptor agonists. Arch Neurol. 2002;59:1084–8.CrossRefPubMed
Metadata
Title
Acute exacerbation of irritable bowel syndrome prevented by prn oral triptan
Authors
Benjamin N. R. Cheyette
Sarah N. R. Cheyette
Publication date
01-12-2016
Publisher
Springer Japan
Published in
Clinical Journal of Gastroenterology / Issue 6/2016
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-016-0689-9

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