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Journal of Cardiothoracic Surgery

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Open Access 01-12-2023 | Acute Coronary Syndrome | Research

Serum cystatin C predicts the risk of non-ST-elevation acute coronary syndrome

Authors: Hao Dong, Dongping Xiao, Yong Tang

Published in: Journal of Cardiothoracic Surgery | Issue 1/2023

Abstract

Objective

Inflammation markers have been proposed as the predictors of adverse cardiac events in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). This study aimed to investigate prognostic value of serum cystatin C (Cys-C) for NSTE-ACS patients.

Methods

Cys-C, neutrophil to lymphocyte ratio (NLR) and high-sensitivity C-reactive protein (hsCRP) were examined in 212 NSTE-ACS patients and 60 controls. Global registry of acute coronary events (GRACE) score and major adverse cardiac events (MACE) in NSTE-ACS patients were recorded.

Results

Cys-C level in the serum was significantly higher in NSTE-ACS patients than in control, and was positively correlated with hsCRP level and NLR as well as GRACE score at admission and 6 months after discharge in NSTE-ACS patients. Serum Cys-C level was identified as a new predictor of MACE.

Conclusion

Serum Cys-C level may be an inflammation biomarker in patients with NSTE-ACS, and could be used as an independent predictor of MACE.

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Title: Serum cystatin C predicts the risk of non-ST-elevation acute coronary syndrome
Authors: Hao Dong
Dongping Xiao
Yong Tang
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Acute Coronary Syndrome
Biomarkers
Published in: Journal of Cardiothoracic Surgery / Issue 1/2023
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/s13019-023-02465-1

2024 ASCO Annual Meeting

Springer Medicine

Serum cystatin C predicts the risk of non-ST-elevation acute coronary syndrome

Abstract

Objective

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Objective

Methods

Results

Conclusion

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