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Journal of Medical Case Reports

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Open Access 01-12-2015 | Case report

Acquired hemophagocytic syndrome related to parainfluenza virus infection: case report

Authors: Nicole Beffermann, Javier Pilcante, Mauricio Sarmiento

Published in: Journal of Medical Case Reports | Issue 1/2015

Abstract

Introduction

We present the case of a patient with acquired hemophagocytic syndrome secondary to parainfluenza virus infection, a complication that has not, to the best of our knowledge, been previously reported.

Case presentation

A 33-year-old Chilean man with fever secondary to parainfluenza 2 virus infection developed progressive cholestasis, hepatosplenomegaly, cytopenia and an increased ferritin level (>2000IU/L). A bone marrow analysis showed hemophagocytosis. Our patient received HLH-94 chemotherapy, and he achieved complete and sustained remission after a two-year follow-up, without the need for hematopoietic stem cell transplantation.

Conclusion

Hemophagocytic syndrome is a severe disease with high mortality. A high index of suspicion is essential to improve survival. A viral etiology is frequent and although Epstein-Barr virus is the most frequently associated, other viruses like parainfluenza can cause this disease.

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Title: Acquired hemophagocytic syndrome related to parainfluenza virus infection: case report
Authors: Nicole Beffermann
Javier Pilcante
Mauricio Sarmiento
Publication date: 01-12-2015
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-015-0552-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Acquired hemophagocytic syndrome related to parainfluenza virus infection: case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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