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Published in: Journal of Medical Case Reports 1/2015

Open Access 01-12-2015 | Case report

Solitary metastasis to the breast after complete resection of encapsulated type AB thymoma: a case report

Authors: Pei-Wen Huang, Kuo-Ming Chang

Published in: Journal of Medical Case Reports | Issue 1/2015

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Abstract

Introduction

Type AB thymoma is generally considered a benign tumor with excellent prognosis. Rare case reports of type A and AB thymomas with recurrence and metastasis have been documented, although extrathoracic metastases are extremely rare. To the best of our knowledge, this is the first reported case of type AB thymoma with solitary metastasis to the breast.

Case presentation

We describe an 83-year-old Taiwanese woman with a metastatic thymoma to the breast 10 years after complete resection of noninvasive and encapsulated primary tumor, and analyze the possible factors to explain the recurrence and metastasis of the stage I thymomas.

Conclusions

Even a clinically benign tumor such as type AB thymoma still has a possibility of metastasizing to an unusual site. When any uncommon tumor presents in any site, a suspicion of secondary neoplasm and thorough clinical history are required.
Literature
1.
go back to reference Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC. The WHO classification of tumours: pathology and genetics of tumours of the lung, pleura, thymus and heart, chapter 3 tumours of the thymus. Lyon: IARC Press; 2004. p. 148–53. Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC. The WHO classification of tumours: pathology and genetics of tumours of the lung, pleura, thymus and heart, chapter 3 tumours of the thymus. Lyon: IARC Press; 2004. p. 148–53.
2.
go back to reference Nomori H, Watanabe K, Ohtsuka T, Naruke T, Suemasu K, Orikasa H, et al. Pulmonary metastasis 12 years after resection of thymoma with microscopic capsule invasion. Jpn J Clin Oncol. 2004;34:630–3.CrossRefPubMed Nomori H, Watanabe K, Ohtsuka T, Naruke T, Suemasu K, Orikasa H, et al. Pulmonary metastasis 12 years after resection of thymoma with microscopic capsule invasion. Jpn J Clin Oncol. 2004;34:630–3.CrossRefPubMed
3.
go back to reference Jain RK, Mehta RJ, Henley JD, Kesler KA, Loehrer PJ, Badve S. WHO types A and AB thymomas: not always benign. Mod Pathol. 2010;23:1641–9.CrossRefPubMed Jain RK, Mehta RJ, Henley JD, Kesler KA, Loehrer PJ, Badve S. WHO types A and AB thymomas: not always benign. Mod Pathol. 2010;23:1641–9.CrossRefPubMed
4.
go back to reference Lee SK, Kim WW, Kim SH, Hur SM, Kim S, Choi JH, et al. Characteristics of metastasis in the breast from extramammary malignancies. J Surg Oncol. 2010;101:137–40.CrossRefPubMed Lee SK, Kim WW, Kim SH, Hur SM, Kim S, Choi JH, et al. Characteristics of metastasis in the breast from extramammary malignancies. J Surg Oncol. 2010;101:137–40.CrossRefPubMed
5.
go back to reference Kwon GY, Hong SA, Hong ME, Park ES, Yoo JH, Lee TJ. Fine needle aspiration biopsy for the diagnosis of thymoma metastatic to the breast: a case report. Acta Cytol. 2010;54:798–802.PubMed Kwon GY, Hong SA, Hong ME, Park ES, Yoo JH, Lee TJ. Fine needle aspiration biopsy for the diagnosis of thymoma metastatic to the breast: a case report. Acta Cytol. 2010;54:798–802.PubMed
7.
go back to reference Lewis JE, Wick MR, Scheithauer BW, Bernatz PE, Taylor WF. Thymoma. A clinicopathologic review. Cancer. 1987;60:2727–43.CrossRefPubMed Lewis JE, Wick MR, Scheithauer BW, Bernatz PE, Taylor WF. Thymoma. A clinicopathologic review. Cancer. 1987;60:2727–43.CrossRefPubMed
8.
go back to reference Regnard JF, Magdeleinat P, Dromer C, Dulmet E, de Montpreville V, Levi JF, et al. Prognostic factors and long-term results after thymoma resection: a series of 307 patients. J Thorac Cardiovasc Surg. 1996;112:376–84.CrossRefPubMed Regnard JF, Magdeleinat P, Dromer C, Dulmet E, de Montpreville V, Levi JF, et al. Prognostic factors and long-term results after thymoma resection: a series of 307 patients. J Thorac Cardiovasc Surg. 1996;112:376–84.CrossRefPubMed
9.
go back to reference Wright CD, Wain JC, Wong DR, Donahue DM, Gaissert HA, Grillo HC, et al. Predictors of recurrence in thymic tumors: importance of invasion, World Health Organization histology, and size. J Thorac Cardiovasc Surg. 2005;130:1413–21.CrossRefPubMed Wright CD, Wain JC, Wong DR, Donahue DM, Gaissert HA, Grillo HC, et al. Predictors of recurrence in thymic tumors: importance of invasion, World Health Organization histology, and size. J Thorac Cardiovasc Surg. 2005;130:1413–21.CrossRefPubMed
10.
go back to reference Pescarmona E, Rendina EA, Venuta F, Ricci C, Baroni CD. Recurrent thymoma: evidence for histological progression. Histopathology. 1995;27:445–9.CrossRefPubMed Pescarmona E, Rendina EA, Venuta F, Ricci C, Baroni CD. Recurrent thymoma: evidence for histological progression. Histopathology. 1995;27:445–9.CrossRefPubMed
Metadata
Title
Solitary metastasis to the breast after complete resection of encapsulated type AB thymoma: a case report
Authors
Pei-Wen Huang
Kuo-Ming Chang
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2015
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-015-0551-6

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