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06-09-2023 | Achondroplasia | Review

Recommendations for neuroradiological examinations in children living with achondroplasia: a European Society of Pediatric Radiology and European Society of Neuroradiology opinion paper

Authors: Jenny Wright, Moira Cheung, Ata Siddiqui, Jonathan Lucas, Alistair Calder, Maria I. Argyropoulou, Owen J. Arthurs, Pablo Caro-Dominguez, Dominic Thompson, Mariasavina Severino, Felice D’Arco, the members of the ESPR Neuroradiology Taskforce, the members of the ESNR Pediatric Subcommittee

Published in: Pediatric Radiology | Issue 12/2023

Abstract

Children living with achondroplasia are at an increased risk of developing neurological complications, which may be associated with acute and life-altering events. To remediate this risk, the timely acquisition of effective neuroimaging that can help to guide clinical management is essential. We propose imaging protocols and follow-up strategies for evaluating the neuroanatomy of these children and to effectively identify potential neurological complications, including compression at the cervicomedullary junction secondary to foramen magnum stenosis, spinal deformity and spinal canal stenosis. When compiling these recommendations, emphasis has been placed on reducing scan times and avoiding unnecessary radiation exposure. Standardized imaging protocols are important to ensure that clinically useful neuroimaging is performed in children living with achondroplasia and to ensure reproducibility in future clinical trials. The members of the European Society of Pediatric Radiology (ESPR) Neuroradiology Taskforce and European Society of Neuroradiology pediatric subcommittee, together with clinicians and surgeons with specific expertise in achondroplasia, wrote this opinion paper. The research committee of the ESPR also endorsed the final draft. The rationale for these recommendations is based on currently available literature, supplemented by best practice opinion from radiologists and clinicians with subject-specific expertise.

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Title: Recommendations for neuroradiological examinations in children living with achondroplasia: a European Society of Pediatric Radiology and European Society of Neuroradiology opinion paper
Authors: Jenny Wright
Moira Cheung
Ata Siddiqui
Jonathan Lucas
Alistair Calder
Maria I. Argyropoulou
Owen J. Arthurs
Pablo Caro-Dominguez
Dominic Thompson
Mariasavina Severino
Felice D’Arco
the members of the ESPR Neuroradiology Taskforce
the members of the ESNR Pediatric Subcommittee
Publication date: 06-09-2023
Publisher: Springer Berlin Heidelberg
Keywords: Achondroplasia
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Spinal Stenosis
Computed Tomography
Computed Tomography
Pediatric Radiology
Pediatric Radiology
Published in: Pediatric Radiology / Issue 12/2023
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-023-05728-0

Keynote webinar | Spotlight on medication adherence

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Recommendations for neuroradiological examinations in children living with achondroplasia: a European Society of Pediatric Radiology and European Society of Neuroradiology opinion paper

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Keynote webinar | Spotlight on medication adherence

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