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01-12-2010 | Diagnostic Neuroradiology

Accuracy of the detection of infratentorial stroke lesions using perfusion CT: an experimenter-blinded study

Authors: In Hyouk Lee, Joshua H. You, Ji Yong Lee, Kum Whang, Myung Soon Kim, Young Ju Kim, Myeong Sub Lee, Brain Research Group

Published in: Neuroradiology | Issue 12/2010

Abstract

Introduction

Although perfusion CT (PCT) for the detection of supratentorial stroke is well established, there is a dearth of evidence of its effectiveness in the detection of infratentorial stroke. Hence, this study compared sensitivity, specificity, and accuracy of PCT maps between infratentorial and supratentorial stroke lesions.

Methods

One hundred patients with acute stroke who had successfully undergone near whole-brain PCT with the toggling table technique and follow-up MRI were included. Wilcoxon Mann–Whitney test was performed at P < 0.01.

Results

There was no significant statistical difference in the accuracy (91.79% vs. 93.23% in regional cerebral blood volume; 92.26% vs. 95.31% in regional cerebral blood flow; 89.17% vs. 92.71% in mean transit time; 89.76% vs. 92.19% in time to peak; P > 0.01 in all PCT maps) between supratentorial and infratentorial stroke. Also, there was no remarkable difference in both sensitivity and specificity of PCT maps.

Conclusion

This was the first study to investigate the accuracy of PCT with the toggling table technique in detection of infratentorial stroke lesions. Clinically, PCT is highly reliable and accurate in detecting infratentorial stroke lesions.

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Title: Accuracy of the detection of infratentorial stroke lesions using perfusion CT: an experimenter-blinded study
Authors: In Hyouk Lee
Joshua H. You
Ji Yong Lee
Kum Whang
Myung Soon Kim
Young Ju Kim
Myeong Sub Lee
Brain Research Group
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 12/2010
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-010-0689-2

2024 ASCO Annual Meeting

Springer Medicine

Accuracy of the detection of infratentorial stroke lesions using perfusion CT: an experimenter-blinded study

Abstract

Introduction

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusion

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