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Neuroradiology

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01-12-2010 | Functional Neuroradiology

Functional MRI of tongue motor tasks in patients with tongue cancer: observations before and after partial glossectomy

Authors: Samantha Haupage, Kyung K. Peck, Ryan C. Branski, Meier Hsu, Andrei Holodny, Dennis Kraus

Published in: Neuroradiology | Issue 12/2010

Abstract

Introduction

The current study seeks to provide preliminary data regarding this central, adaptive response during tongue motor tasks utilizing functional magnetic resonance imaging (fMRI) before and after glossectomy.

Methods

Six patients, with confirmed histological diagnoses of oral tongue cancer, underwent fMRI before and 6 months after partial glossectomy. These data were compared to nine healthy controls. All subjects performed three tongue motor tasks during fMRI: tongue tapping (TT), dry swallow (Dry), and wet swallow (Wet).

Results

Following surgery, increased activation was subjectively observed in the superior parietal lobule, supplementary motor area, and anterior cingulate. Region of interest (ROI) analysis of the precentral gyrus confirmed increased cortical activity following surgery. In addition, comparisons between pre-surgical scans and controls suggested the dry swallow task was sensitive to elicit tongue-related activation in the precentral gyrus (p ≤ 0.05).

Conclusions

The adaptive changes in the cortex following partial glossectomy reflect recruitment of the parietal, frontal, and cingulate cortex during tongue motor tasks. In addition, post-operative activation patterns more closely approximated control levels than the pre-operative scans. Furthermore, the dry swallow task appears most specific to elicit tongue-related cortical activity.

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Title: Functional MRI of tongue motor tasks in patients with tongue cancer: observations before and after partial glossectomy
Authors: Samantha Haupage
Kyung K. Peck
Ryan C. Branski
Meier Hsu
Andrei Holodny
Dennis Kraus
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: Neuroradiology / Issue 12/2010
Print ISSN: 0028-3940
Electronic ISSN: 1432-1920
DOI: https://doi.org/10.1007/s00234-010-0748-8

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Functional MRI of tongue motor tasks in patients with tongue cancer: observations before and after partial glossectomy

Abstract

Introduction

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusions

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