Skip to main content
Top
Published in: Clinical Oral Investigations 3/2019

01-03-2019 | Original Article

Ability of two single-step restorative materials to avoid crown darkening caused by intracanal minocycline paste

Authors: Ane Poly, Fernando Marques, Sandra R. Fidel, Antonio Fernando Monnerat, Luciana M. Sassone

Published in: Clinical Oral Investigations | Issue 3/2019

Login to get access

Abstract

Objectives

This study aimed to quantitatively assess the ability of two single-step restorative materials to avoid crown darkening caused by the use of minocycline as an intracanal medicament.

Materials and methods

After coronal access and instrumentation, 120 maxillary incisors were divided into four groups (n = 30). Two experimental groups according to the restorative material applied to the inner walls of the access cavity: OB, OptiBond All-In-One + minocycline intracanal paste; U200, RelyX U200 + minocycline intracanal paste. Two control groups without restorative materials: MIN, minocycline intracanal paste and SL, saline intracanal. Color determination was performed using a spectrophotometer at five time points, immediately after materials were applied (baseline), and at 7, 14, 21, and 28 days from the baseline.

Results

Decrease in the mean values of L* (luminosity) was observed after insertion of minocycline paste in all groups at all time points. Statistically significant differences were absent between the time points (P > .05). After 28 days, MIN showed significantly more darkening (ΔL*) (− 10.6 ± 7.3) than OB (− 5.4 ± 6.2), U200 (− 5.8 ± 3.9) and SL (− 2.3 ± 1.2) (P < .05).

Conclusions

Crown darkening can be minimized by the previous application of RelyX U200 or OptiBond All-In-One to the inner walls of the access cavity before a minocycline-containing paste is applied as an intracanal medication.

Clinical relevance

The American Association of Endodontists Clinical Considerations for Regenerative Procedures in necrotic immature teeth suggests the triple antibiotic paste as an intracanal medication (2018). However, discoloration and crown darkening are common unfavorable outcomes. The clinical protocol suggested in this paper has shown to be able to minimize crown darkening, predictably leading to a better patient-centered clinical success.
Literature
1.
go back to reference Nygaard-Østby B (1961) The role of the blood clot in endodontic therapy: an experimental histological study. Acta Odontol Scand 79:333–349 Nygaard-Østby B (1961) The role of the blood clot in endodontic therapy: an experimental histological study. Acta Odontol Scand 79:333–349
2.
go back to reference Nygaard-Ostby B, Hjortdal O (1971) Tissue formation in the root canal following pulp removal. Scand J Dent Res 79:333–348PubMed Nygaard-Ostby B, Hjortdal O (1971) Tissue formation in the root canal following pulp removal. Scand J Dent Res 79:333–348PubMed
3.
go back to reference Banchs F, Trope M (2004) Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 30:196–200CrossRefPubMed Banchs F, Trope M (2004) Revascularization of immature permanent teeth with apical periodontitis: new treatment protocol? J Endod 30:196–200CrossRefPubMed
5.
6.
go back to reference Skoglund A, Tronstad L (1981) Pulpal changes in replanted and autotransplanted immature teeth of dogs. J Endod 7:309–316CrossRefPubMed Skoglund A, Tronstad L (1981) Pulpal changes in replanted and autotransplanted immature teeth of dogs. J Endod 7:309–316CrossRefPubMed
7.
go back to reference Cvek M (1992) Prognosis of luxated non-vital maxillary incisors treated with calcium hydroxide and filled with gutta-percha. A retrospective clinical study. Endod Dent Traumatol 8:45–55CrossRefPubMed Cvek M (1992) Prognosis of luxated non-vital maxillary incisors treated with calcium hydroxide and filled with gutta-percha. A retrospective clinical study. Endod Dent Traumatol 8:45–55CrossRefPubMed
8.
go back to reference Fouad AF, Nosrat A (2013) Pulp regeneration in previously infected root canal space. Endod Top 28:24–37CrossRef Fouad AF, Nosrat A (2013) Pulp regeneration in previously infected root canal space. Endod Top 28:24–37CrossRef
9.
go back to reference Hoshino E, Kurihara-Ando N, Sato I et al (1996) In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J 29:125–130CrossRefPubMed Hoshino E, Kurihara-Ando N, Sato I et al (1996) In-vitro antibacterial susceptibility of bacteria taken from infected root dentine to a mixture of ciprofloxacin, metronidazole and minocycline. Int Endod J 29:125–130CrossRefPubMed
10.
go back to reference Parasuraman VR, Muljibhai BS (2012) 3Mix-MP in endodontics—an overview. IOSR-JDMS 3:36–45CrossRef Parasuraman VR, Muljibhai BS (2012) 3Mix-MP in endodontics—an overview. IOSR-JDMS 3:36–45CrossRef
11.
go back to reference Takushige T, Hataoka H, Ando M, Hoshino E (2009) Endodontic retreatment using 3Mix-MP without removal of previous root canal obturation. J LSTR Ther 8:3–7 Takushige T, Hataoka H, Ando M, Hoshino E (2009) Endodontic retreatment using 3Mix-MP without removal of previous root canal obturation. J LSTR Ther 8:3–7
14.
go back to reference Reynolds K, Johnson J, Cohenca N (2009) Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report. Int Endod J 42:84–92CrossRefPubMed Reynolds K, Johnson J, Cohenca N (2009) Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report. Int Endod J 42:84–92CrossRefPubMed
15.
go back to reference Petrino J, Boda K, Shambarger S et al (2010) Challenges in regenerative endodontics: a case series. J Endod 36:536–541CrossRefPubMed Petrino J, Boda K, Shambarger S et al (2010) Challenges in regenerative endodontics: a case series. J Endod 36:536–541CrossRefPubMed
16.
go back to reference Nosrat A, Seifi A, Asgary S (2011) Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. J Endod 37:562–567CrossRefPubMed Nosrat A, Seifi A, Asgary S (2011) Regenerative endodontic treatment (revascularization) for necrotic immature permanent molars: a review and report of two cases with a new biomaterial. J Endod 37:562–567CrossRefPubMed
17.
go back to reference Porter ML, Münchow EA, Albuquerque MT et al (2016) Effects of novel 3-dimensional antibiotic-containing electrospun scaffolds on dentin discoloration. J Endod 42:106–112CrossRefPubMed Porter ML, Münchow EA, Albuquerque MT et al (2016) Effects of novel 3-dimensional antibiotic-containing electrospun scaffolds on dentin discoloration. J Endod 42:106–112CrossRefPubMed
18.
go back to reference Thelen DS, Trovik TA, Bardsen A (2011) Impact of traumatic dental injuries with unmet treatment need on daily life among Albanian adolescents: a case-control study. Dent Traumatol 27:88–94CrossRefPubMed Thelen DS, Trovik TA, Bardsen A (2011) Impact of traumatic dental injuries with unmet treatment need on daily life among Albanian adolescents: a case-control study. Dent Traumatol 27:88–94CrossRefPubMed
19.
go back to reference Viegas CM, Scarpelli AC, Carvalho AC, Ferreira Fde M, Pordeus IA, Paiva SM (2012) Impact of traumatic dental injury on quality of life among Brazilian preschool children and their families. Pediatr Dent 34:300–306PubMed Viegas CM, Scarpelli AC, Carvalho AC, Ferreira Fde M, Pordeus IA, Paiva SM (2012) Impact of traumatic dental injury on quality of life among Brazilian preschool children and their families. Pediatr Dent 34:300–306PubMed
20.
go back to reference Krisdapong S, Prasertsom P, Rattanarangsima K, Sheiham A (2014) Associations between perceived needs for dental treatment, oral health-related quality of life and oral diseases in school-aged Thai children. Community Dent Oral Epidemiol 42:323–332CrossRefPubMed Krisdapong S, Prasertsom P, Rattanarangsima K, Sheiham A (2014) Associations between perceived needs for dental treatment, oral health-related quality of life and oral diseases in school-aged Thai children. Community Dent Oral Epidemiol 42:323–332CrossRefPubMed
21.
go back to reference Miller EK, Lee JY, Tawil PZ, Teixeira FB, Wann WF Jr (2012) Emerging therapies for the management of traumatized immature permanent incisors. Pediatr Dent 34:66–69PubMed Miller EK, Lee JY, Tawil PZ, Teixeira FB, Wann WF Jr (2012) Emerging therapies for the management of traumatized immature permanent incisors. Pediatr Dent 34:66–69PubMed
22.
go back to reference McTigue DJ, Subramanian K, Kumar A (2013) Management of immature permanent teeth with pulpal necrosis-a case series. Pediatr Dent 35:55–60PubMed McTigue DJ, Subramanian K, Kumar A (2013) Management of immature permanent teeth with pulpal necrosis-a case series. Pediatr Dent 35:55–60PubMed
23.
go back to reference Kim JH, Kim Y, Shin SJ, Park JW, Jung IY (2010) Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 36:1086–1091CrossRefPubMed Kim JH, Kim Y, Shin SJ, Park JW, Jung IY (2010) Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. J Endod 36:1086–1091CrossRefPubMed
24.
go back to reference Kirchhoff AL, Raldi DP, Salles AC, Cunha RS, Mello I (2015) Tooth discolouration and internal bleaching after the use of triple antibiotic paste. Int Endod J 48:1181–1187CrossRefPubMed Kirchhoff AL, Raldi DP, Salles AC, Cunha RS, Mello I (2015) Tooth discolouration and internal bleaching after the use of triple antibiotic paste. Int Endod J 48:1181–1187CrossRefPubMed
25.
go back to reference Santos LG, Felippe WT, Souza BD et al (2017) Crown discoloration promoted by materials used in regenerative endodontic procedures and effect of dental bleaching: spectrophotometric analysis. J Appl Oral Sci 25:234–242CrossRefPubMedPubMedCentral Santos LG, Felippe WT, Souza BD et al (2017) Crown discoloration promoted by materials used in regenerative endodontic procedures and effect of dental bleaching: spectrophotometric analysis. J Appl Oral Sci 25:234–242CrossRefPubMedPubMedCentral
27.
go back to reference Samra APB, Pereira SK, Delgado LC, Borges CP (2008) Color stability evaluation of aesthetic restorative materials. Braz Oral Res 22:205–210CrossRefPubMed Samra APB, Pereira SK, Delgado LC, Borges CP (2008) Color stability evaluation of aesthetic restorative materials. Braz Oral Res 22:205–210CrossRefPubMed
28.
go back to reference Seghi RR, Johnston WM, O’Brien WJ (1986) Spectrophotometric analysis of color differences between porcelain systems. J Prosthet Dent 56:35–40CrossRefPubMed Seghi RR, Johnston WM, O’Brien WJ (1986) Spectrophotometric analysis of color differences between porcelain systems. J Prosthet Dent 56:35–40CrossRefPubMed
29.
go back to reference Kahler B, Rossi-Fedele G, Chugal N, Lin LM (2017) An evidence-based review of the efficacy of treatment approaches for immature permanent teeth with pulp necrosis. J Endod 43:1052–1057CrossRefPubMed Kahler B, Rossi-Fedele G, Chugal N, Lin LM (2017) An evidence-based review of the efficacy of treatment approaches for immature permanent teeth with pulp necrosis. J Endod 43:1052–1057CrossRefPubMed
30.
go back to reference Hargreaves KM, Geisler T, Henry M, Wang Y (2008) Regeneration potential of the young permanent tooth: where does the future hold? J Endod 34:S51–S56CrossRefPubMed Hargreaves KM, Geisler T, Henry M, Wang Y (2008) Regeneration potential of the young permanent tooth: where does the future hold? J Endod 34:S51–S56CrossRefPubMed
31.
go back to reference Thibodeau B, Trope M (2007) Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatric Dent 29:47–50 Thibodeau B, Trope M (2007) Pulp revascularization of a necrotic infected immature permanent tooth: case report and review of the literature. Pediatric Dent 29:47–50
32.
go back to reference Trope M (2010) Treatment of the immature tooth with a non-vital pulp and apical periodontitis. Dent Clin N Am 54:313–324CrossRefPubMed Trope M (2010) Treatment of the immature tooth with a non-vital pulp and apical periodontitis. Dent Clin N Am 54:313–324CrossRefPubMed
33.
go back to reference Tanase S, Tsuchiya H, Yao J, Ohmoto S, Nobuhiko Takagi, Yoshida S (1998) Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics aplication to discolored teeth. J Chromatogr B 706:279–285CrossRef Tanase S, Tsuchiya H, Yao J, Ohmoto S, Nobuhiko Takagi, Yoshida S (1998) Reversed-phase ion-pair chromatographic analysis of tetracycline antibiotics aplication to discolored teeth. J Chromatogr B 706:279–285CrossRef
34.
go back to reference Thompson A, Kahler B (2010) Regenerative endodontics—biologically-based treatment for immature permanent teeth: a case report and review of the literature. Aust Dent J 55:446–452CrossRef Thompson A, Kahler B (2010) Regenerative endodontics—biologically-based treatment for immature permanent teeth: a case report and review of the literature. Aust Dent J 55:446–452CrossRef
35.
go back to reference Kahler B, Mistry S, Moule A, Ringsmuth AK, Case P, Thomson A, Holcombe T (2014) Revascularization outcomes: a prospective analysis of 16 consecutive cases. J Endod 40:333–338CrossRefPubMed Kahler B, Mistry S, Moule A, Ringsmuth AK, Case P, Thomson A, Holcombe T (2014) Revascularization outcomes: a prospective analysis of 16 consecutive cases. J Endod 40:333–338CrossRefPubMed
36.
go back to reference Kahler B, Rossi-Fedele G (2016) A review of tooth discoloration after regenerative endodontic therapy. J Endod 42:563–569CrossRefPubMed Kahler B, Rossi-Fedele G (2016) A review of tooth discoloration after regenerative endodontic therapy. J Endod 42:563–569CrossRefPubMed
37.
38.
go back to reference Donahue JL, Doodking RJ, Shcawabacher WB, Aeppli DP (1991) Shade color discrimination by men and women. J Prosthet Dent 65:699–703CrossRefPubMed Donahue JL, Doodking RJ, Shcawabacher WB, Aeppli DP (1991) Shade color discrimination by men and women. J Prosthet Dent 65:699–703CrossRefPubMed
39.
go back to reference Paul S, Peter A, Pietrobon N, Hämmerle CHF (2002) Visual and spectrophotometric shade analysis of human teeth. J Dent Res 81:578–582CrossRefPubMed Paul S, Peter A, Pietrobon N, Hämmerle CHF (2002) Visual and spectrophotometric shade analysis of human teeth. J Dent Res 81:578–582CrossRefPubMed
40.
go back to reference Browning WD, Chan DC, Blalock JS, Brackett MG (2009) A comparison of human raters and an intraoral spectrophotometer. Oper Dent 34:337–343CrossRefPubMed Browning WD, Chan DC, Blalock JS, Brackett MG (2009) A comparison of human raters and an intraoral spectrophotometer. Oper Dent 34:337–343CrossRefPubMed
41.
go back to reference Lehmann KM, Igiel C, Schmidtmann I, Scheller H (2010) Four color-measuring devices compared with a spectrophotometric reference system. J Dent 38:e65–e70CrossRefPubMed Lehmann KM, Igiel C, Schmidtmann I, Scheller H (2010) Four color-measuring devices compared with a spectrophotometric reference system. J Dent 38:e65–e70CrossRefPubMed
42.
go back to reference Mehl A, Bosch G, Fischer C, Ender A (2017) In vivo tooth-color measurement with a new 3D intraoral scanning system in comparison to conventional digital and visual color determination methods. Int J Comput Dent 20:343–361PubMed Mehl A, Bosch G, Fischer C, Ender A (2017) In vivo tooth-color measurement with a new 3D intraoral scanning system in comparison to conventional digital and visual color determination methods. Int J Comput Dent 20:343–361PubMed
43.
go back to reference Peutzfeldt A, Asmussen E (2002) Adhesive systems: effect on bond strength of incorrect use. J Adhes Dent 4:233–242PubMed Peutzfeldt A, Asmussen E (2002) Adhesive systems: effect on bond strength of incorrect use. J Adhes Dent 4:233–242PubMed
44.
go back to reference Kim-Pusateri S, Brewer JD, Davis EL, Wee AG (2009) Reliability and accuracy of four dental shade-matching devices. J Prosthet Dent 101:193–199CrossRefPubMed Kim-Pusateri S, Brewer JD, Davis EL, Wee AG (2009) Reliability and accuracy of four dental shade-matching devices. J Prosthet Dent 101:193–199CrossRefPubMed
45.
go back to reference Peutzfeldt A, Vigild M (2001) A survey of the use of dentin-bonding systems in Denmark. Dent Mater 17:211–216CrossRefPubMed Peutzfeldt A, Vigild M (2001) A survey of the use of dentin-bonding systems in Denmark. Dent Mater 17:211–216CrossRefPubMed
Metadata
Title
Ability of two single-step restorative materials to avoid crown darkening caused by intracanal minocycline paste
Authors
Ane Poly
Fernando Marques
Sandra R. Fidel
Antonio Fernando Monnerat
Luciana M. Sassone
Publication date
01-03-2019
Publisher
Springer Berlin Heidelberg
Published in
Clinical Oral Investigations / Issue 3/2019
Print ISSN: 1432-6981
Electronic ISSN: 1436-3771
DOI
https://doi.org/10.1007/s00784-018-2557-0

Other articles of this Issue 3/2019

Clinical Oral Investigations 3/2019 Go to the issue