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01-05-2007 | Original

Ability of family members to predict patient's consent to critical care research

Authors: Magali Ciroldi, Alain Cariou, Christophe Adrie, Djilali Annane, Vincent Castelain, Yves Cohen, Arnaud Delahaye, Luc Marie Joly, Richard Galliot, Maité Garrouste-Orgeas, Laurent Papazian, Fabrice Michel, Nancy Kenstish Barnes, Benoit Schlemmer, Frédéric Pochard, Elie Azoulay

Published in: Intensive Care Medicine | Issue 5/2007

Abstract

Objective

A European Union Directive provides for the designation of a surrogate who can consent to or refuse inclusion of an incapacitated patient in research studies. The accuracy with which surrogates consent to research on behalf of patients has not been evaluated in the intensive care unit (ICU).

Methods

A prospective multicenter study was conducted in ten ICUs of the French Famirea study group between July and October 2004. Two hypothetical studies were simultaneously submitted to the patient, surrogate, and physician at the time that the patient was discharged to a ward. One study involved minimal risk and the other greater-than-minimal risk to the patients.

Results

With the minimal risk study there was patient-surrogate discrepancy in 32% of cases and patient-physician discrepancy in 25%. Corresponding figures with the greater-than-minimal risk study were 42% and 46%. None of the collected variables differed significantly between cases with and without patient-surrogate discrepancy.

Conclusions

Family members designated to serve as surrogate decision makers may fail to accurately consent to research for critically ill patients in one-third to nearly one-half of cases.

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Title: Ability of family members to predict patient's consent to critical care research
Authors: Magali Ciroldi
Alain Cariou
Christophe Adrie
Djilali Annane
Vincent Castelain
Yves Cohen
Arnaud Delahaye
Luc Marie Joly
Richard Galliot
Maité Garrouste-Orgeas
Laurent Papazian
Fabrice Michel
Nancy Kenstish Barnes
Benoit Schlemmer
Frédéric Pochard
Elie Azoulay
Publication date: 01-05-2007
Publisher: Springer Berlin Heidelberg
Published in: Intensive Care Medicine / Issue 5/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-007-0582-6

At a glance: The STEP trials

Springer Medicine

Ability of family members to predict patient's consent to critical care research

Abstract

Objective

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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