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Intensive Care Medicine
Published in: Intensive Care Medicine 5/2007

01-05-2007 | Physiological Note

Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation

Author: Jukka Takala

Published in: Intensive Care Medicine | Issue 5/2007

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Excerpt

In the hypoxemic patient under mechanical ventilation, changes in cardiac output may influence the level of arterial oxygenation, with several and sometimes opposite effects. The purpose of this Physiological Note is to give the reader the physiological background to understand these effects, which are often highly relevant for the bedside management of patients with acute lung injury. …
Literature
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Lumb AB (2000) Distribution of pulmonary ventilation and perfusion. In: Lumb AB (ed) Nunn's applied respiratory physiology, 5th edn. Butterworth-Heinemann, Oxford, UK, pp 163–199
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Ratner ER, Wagner PD (1982) Resolution of the multiple inert gas method for estimating VA/Q maldistribution. Respir Physiol 49:293–313CrossRefPubMed
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Giovannini I, Boldrini G, Sganga G, Castiglioni G, Castagneto M (1983) Quantification of the determinants of arterial hypoxemia in critically ill patients. Crit Care Med 11:644–645CrossRefPubMed
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Dantzker DR, Lynch JP, Weg JG (1980) Depression of cardiac output is a mechanism of shunt reduction in the therapy of acute respiratory failure. Chest 77:636–642CrossRefPubMed
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Freden F, Cigarini I, Mannting F, Hagberg A, Lemaire F, Hedenstierna G (1993) Dependence of shunt on cardiac output in unilobar oleic acid edema: distribution of ventilation and perfusion. Intensive Care Med 19:185–90CrossRefPubMed
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Metadata
Title
Hypoxemia due to increased venous admixture: influence of cardiac output on oxygenation
Author
Jukka Takala
Publication date
01-05-2007
Publisher
Springer Berlin Heidelberg
Published in
Intensive Care Medicine / Issue 5/2007
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI
https://doi.org/10.1007/s00134-007-0546-x

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