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01-12-2017 | AdisInsight Report

Abemaciclib: First Global Approval

Author: Esther S. Kim

Published in: Drugs | Issue 18/2017

Abstract

Abemaciclib (Verzenio™) is an orally administered inhibitor of cyclin-dependent kinases 4 and 6 that is being developed by Eli Lilly and Company. Abemaciclib has been approved in the USA for the treatment of hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer, in combination with fulvestrant in women with disease progression following endocrine therapy, and as monotherapy in adult patients with disease progression following endocrine therapy and prior chemotherapy in the metastatic setting. In addition, abemaciclib is in various stages of development internationally for a variety of cancers. This article summarizes the milestones in the development of abemaciclib leading to its first approval for the treatment of patients with HR-positive, HER2-negative advanced or metastatic breast cancer.

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Title: Abemaciclib: First Global Approval
Author: Esther S. Kim
Publication date: 01-12-2017
Publisher: Springer International Publishing
Published in: Drugs / Issue 18/2017
Print ISSN: 0012-6667
Electronic ISSN: 1179-1950
DOI: https://doi.org/10.1007/s40265-017-0840-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abemaciclib: First Global Approval

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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