Skip to main content
Top
Published in: Surgical Endoscopy 2/2021

01-02-2021 | Abdominal Surgery

Success, safety, and usefulness of right colon retroflexion for the detection of additional colonic lesions not visualized with standard frontal view

Authors: Oscar Nogales, Jon de la Maza, Esperanza Martos, Laura Carrión, Rodrigo Borobia, Luis Lucendo, María López-Ibáñez, Javier García-Lledó, Leticia Pérez-Carazo, Beatriz Merino

Published in: Surgical Endoscopy | Issue 2/2021

Login to get access

Abstract

Background

Missed adenomas are the main concern for endoscopists. Right colon retroflexion (RCR) seems to increase the adenoma detection rate (ADR), but important variation in success and usefulness of this maneuver has been reported in the literature

Aims

Primary objective: to assess additional adenoma detection rate (AADR) detected during the RCR attempt. Secondary objectives: to assess success rates of RCR, variables associated with it, and safety of RCR.

Methods

This is a prospective, unicentric, non-randomized study. Consecutive colonoscopies done by six endoscopists (3 of them with < 3 years of experience and 3 with > 3 years) from March to May 2017 were included. Olympus colonoscopes were used (CF-H190, CF-H180) Demographic, clinical, and endoscopic variables were collected.

Results

463 colonoscopies were included. RCR success rate was 93.1% (431/463 colonoscopies). Forty additional lesions were visualized during RCR in 34/463 colonoscopies (7.3%). Additional adenomas were detected in 31/463 colonoscopies (6.7%; OR 0.07). Histology: low-grade dysplasia adenomas in 29/40 (72.5%) lesions; 3/40 (7.5%), adenomas with high-grade dysplasia; and 7/40 (17.5%) sessile serrated lesions. Additional adenoma detection contributed to modify the colonoscopy surveillance interval in 25 patients (5.4% of the cohort). Variables associated with RCR success in multivariate analysis were no previous abdominal surgery, length of colonoscope insertion in cecum < 80 cm, and use of Olympus 190 series colonoscopes. No differences between endoscopists’ experience were found. RCR was a safe maneuver, with no adverse events in our study.

Conclusions

RCR is a feasible and safe maneuver that can increase ADR, so its routine inclusion in colonoscopy practice should be considered.
Literature
1.
go back to reference Zauber AG, Winawer SJ, O’Brien MJ et al (2012) Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 366:687–696CrossRef Zauber AG, Winawer SJ, O’Brien MJ et al (2012) Colonoscopic polypectomy and long-term prevention of colorectal-cancer deaths. N Engl J Med 366:687–696CrossRef
2.
go back to reference Van Rijn JC, Reitsma JB, Stoker J et al (2006) Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol 101:343–350CrossRef Van Rijn JC, Reitsma JB, Stoker J et al (2006) Polyp miss rate determined by tandem colonoscopy: a systematic review. Am J Gastroenterol 101:343–350CrossRef
3.
go back to reference Rex DK, Cutler CS, Lemmel GT et al (1997) Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology 112:24–28CrossRef Rex DK, Cutler CS, Lemmel GT et al (1997) Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology 112:24–28CrossRef
4.
go back to reference Rex DK (2016) How I approach retroflexion and prevention of right-sided colon cancer following colonoscopy. Am J Gastroenterol 111:9–11CrossRef Rex DK (2016) How I approach retroflexion and prevention of right-sided colon cancer following colonoscopy. Am J Gastroenterol 111:9–11CrossRef
5.
go back to reference Chandran S, Parker F, Vaughan R et al (2015) Right-sided adenoma detection with retroflexion versus forward-view colonoscopy. Gastrointest Endosc 81:608–613CrossRef Chandran S, Parker F, Vaughan R et al (2015) Right-sided adenoma detection with retroflexion versus forward-view colonoscopy. Gastrointest Endosc 81:608–613CrossRef
6.
go back to reference Baumann UA (2009) Does retroflexion improve adenoma miss rates on the right side of the colon when using a pediatric variablestiffness colonoscope during routine colonoscopy? Endoscopy 41:654CrossRef Baumann UA (2009) Does retroflexion improve adenoma miss rates on the right side of the colon when using a pediatric variablestiffness colonoscope during routine colonoscopy? Endoscopy 41:654CrossRef
7.
go back to reference Gaddam S, Hollander TG, Edmundowicz SA et al (2012) Extending right colon retroflexion to the splenic flexure. Gastroenterology 142:S227 Gaddam S, Hollander TG, Edmundowicz SA et al (2012) Extending right colon retroflexion to the splenic flexure. Gastroenterology 142:S227
8.
go back to reference Kim HU, Boo SJ, Na SY et al (2015) Additional polyp detection rate using colonoscopic retroflexion in right colon. Korean J Gastroenterol 65:90–98CrossRef Kim HU, Boo SJ, Na SY et al (2015) Additional polyp detection rate using colonoscopic retroflexion in right colon. Korean J Gastroenterol 65:90–98CrossRef
9.
go back to reference Vargas AL, Alburquerque M, Figa M et al (2015) Ascending colon exploration by retroviewing: technical feasibility and diagnosis performance. Gastrointest Endosc 81:AB293CrossRef Vargas AL, Alburquerque M, Figa M et al (2015) Ascending colon exploration by retroviewing: technical feasibility and diagnosis performance. Gastrointest Endosc 81:AB293CrossRef
10.
go back to reference Kushnir VM, Oh YS, Hollander T et al (2015) Impact of retroflexion vs second forward view examination of the right colon on adenoma detection: a comparison study. Am J Gastroenterol 110(3):415–422CrossRef Kushnir VM, Oh YS, Hollander T et al (2015) Impact of retroflexion vs second forward view examination of the right colon on adenoma detection: a comparison study. Am J Gastroenterol 110(3):415–422CrossRef
11.
go back to reference Lakoff J, Paszat LF, Saskin R, Rabeneck L (2008) Risk of developing proximal versus distal colorectal cancer after a negative colonoscopy: a population-based study. Clin Gastroenterol Hepatol 6:1117–1121CrossRef Lakoff J, Paszat LF, Saskin R, Rabeneck L (2008) Risk of developing proximal versus distal colorectal cancer after a negative colonoscopy: a population-based study. Clin Gastroenterol Hepatol 6:1117–1121CrossRef
12.
go back to reference Singh H, Nugent Z, Demers AA, Kliewer EV, Mahmud SM, Bernstein CN (2010) The reduction in colorectal cancer mortality after colonoscopy varies by site of the cancer. Gastroenterology 139:1128–1137CrossRef Singh H, Nugent Z, Demers AA, Kliewer EV, Mahmud SM, Bernstein CN (2010) The reduction in colorectal cancer mortality after colonoscopy varies by site of the cancer. Gastroenterology 139:1128–1137CrossRef
13.
go back to reference Singh H, Nugent Z, Mahmud SM, Demers AA, Bernstein CN (2010) Predictors of colorectal cancer after negative colonoscopy: a population-based study. Am J Gastroenterol 105:663–673CrossRef Singh H, Nugent Z, Mahmud SM, Demers AA, Bernstein CN (2010) Predictors of colorectal cancer after negative colonoscopy: a population-based study. Am J Gastroenterol 105:663–673CrossRef
14.
go back to reference Soetikno RM, Kaltenbach T, Rouse RV et al (2008) Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults. JAMA 299:1027–1035CrossRef Soetikno RM, Kaltenbach T, Rouse RV et al (2008) Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adults. JAMA 299:1027–1035CrossRef
15.
go back to reference Hetzel JT, Huang CS, Coukos JA et al (2010) Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol 105:2656–2664CrossRef Hetzel JT, Huang CS, Coukos JA et al (2010) Variation in the detection of serrated polyps in an average risk colorectal cancer screening cohort. Am J Gastroenterol 105:2656–2664CrossRef
17.
go back to reference Harrison M, Singh N, Rex DK (2004) Impact of proximal colon retroflexion on adenoma miss rates. Am J Gastroenterol 99:519–522CrossRef Harrison M, Singh N, Rex DK (2004) Impact of proximal colon retroflexion on adenoma miss rates. Am J Gastroenterol 99:519–522CrossRef
18.
go back to reference Lee HS, Jeon SW, Park HY, Yeo SJ (2017) Improved detection of right colon adenomas with additional retroflexion following two forward-view examinations: a prospective study. Endoscopy 49(4):334–341PubMed Lee HS, Jeon SW, Park HY, Yeo SJ (2017) Improved detection of right colon adenomas with additional retroflexion following two forward-view examinations: a prospective study. Endoscopy 49(4):334–341PubMed
19.
go back to reference Hewett DG, Rex DK (2011) Miss rate of right-sided colon examination during colonoscopy defined by retroflexion: an observational study. Gastrointest Endosc 74:246–252CrossRef Hewett DG, Rex DK (2011) Miss rate of right-sided colon examination during colonoscopy defined by retroflexion: an observational study. Gastrointest Endosc 74:246–252CrossRef
20.
go back to reference Lee HS, Jeon SW (2015) Is retroflexion helpful in detecting adenomas in the right colon?: A single center interim analysis. Intest Res 13(4):326–331CrossRef Lee HS, Jeon SW (2015) Is retroflexion helpful in detecting adenomas in the right colon?: A single center interim analysis. Intest Res 13(4):326–331CrossRef
21.
go back to reference Triantafyllou K, Tziatzios G, Sioulas AD et al (2016) Diagnostic yield of scope retroflexion in the right colon: a prospective cohort study. Dig Liver Dis 48:176–181CrossRef Triantafyllou K, Tziatzios G, Sioulas AD et al (2016) Diagnostic yield of scope retroflexion in the right colon: a prospective cohort study. Dig Liver Dis 48:176–181CrossRef
Metadata
Title
Success, safety, and usefulness of right colon retroflexion for the detection of additional colonic lesions not visualized with standard frontal view
Authors
Oscar Nogales
Jon de la Maza
Esperanza Martos
Laura Carrión
Rodrigo Borobia
Luis Lucendo
María López-Ibáñez
Javier García-Lledó
Leticia Pérez-Carazo
Beatriz Merino
Publication date
01-02-2021
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 2/2021
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-020-07424-8

Other articles of this Issue 2/2021

Surgical Endoscopy 2/2021 Go to the issue