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Published in: Abdominal Radiology 2/2024

13-12-2023 | Abdominal Aortic Aneurysm | Kidneys, Ureters, Bladder, Retroperitoneum

Automated detection of incidental abdominal aortic aneurysms on computed tomography

Authors: Devina Chatterjee, Thomas C. Shen, Pritam Mukherjee, Sungwon Lee, John W. Garrett, Nicholas Zacharias, Perry J. Pickhardt, Ronald M. Summers

Published in: Abdominal Radiology | Issue 2/2024

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Abstract

Purpose

To detect and assess abdominal aortic aneurysms (AAAs) on CT in a large asymptomatic adult patient population using fully-automated deep learning software.

Materials and methods

The abdominal aorta was segmented using a fully-automated deep learning model trained on 66 manually-segmented abdominal CT scans from two datasets. The axial diameters of the segmented aorta were extracted to detect the presence of AAAs—maximum axial aortic diameter greater than 3 cm were labeled as AAA positive. The trained system was then externally-validated on CT colonography scans of 9172 asymptomatic outpatients (mean age, 57 years) referred for colorectal cancer screening. Using a previously-validated automated calcified atherosclerotic plaque detector, we correlated abdominal aortic Agatston and volume scores with the presence of AAA.

Results

The deep learning software detected AAA on the external validation dataset with a sensitivity, specificity, and AUC of 96%, (95% CI 89%, 100%), 96% (96%, 97%), and 99% (98%, 99%) respectively. The Agatston and volume scores of reported AAA-positive cases were statistically significantly greater than those of reported AAA-negative cases (p < 0.0001). Using plaque alone as a AAA detector, at a threshold Agatston score of 2871, the sensitivity and specificity were 84% (73%, 94%) and 87% (86%, 87%), respectively.

Conclusion

Fully-automated detection and assessment of AAA on CT is feasible and accurate. There was a strong statistical association between the presence of AAA and the quantity of abdominal aortic calcified atherosclerotic plaque.
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Metadata
Title
Automated detection of incidental abdominal aortic aneurysms on computed tomography
Authors
Devina Chatterjee
Thomas C. Shen
Pritam Mukherjee
Sungwon Lee
John W. Garrett
Nicholas Zacharias
Perry J. Pickhardt
Ronald M. Summers
Publication date
13-12-2023
Publisher
Springer US
Published in
Abdominal Radiology / Issue 2/2024
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-023-04119-1

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