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Open Access 01-12-2022 | Study protocol

ABBaH teens: Activity Breaks for Brain Health in adolescents: study protocol for a randomized crossover trial

Authors: Emerald G. Heiland, Karin Kjellenberg, Olga Tarassova, Maria Fernström, Gisela Nyberg, Maria M. Ekblom, Björg Helgadottir, Örjan Ekblom

Published in: Trials | Issue 1/2022

Abstract

Background

Physical activity breaks are widely being implemented in school settings as a solution to increase academic performance and reduce sitting time. However, the underlying physiological mechanisms suggested to improve cognitive function from physical activity and the frequency, intensity, and duration of the breaks remain unknown. This study will investigate the effects of frequent, short physical activity breaks during prolonged sitting on task-related prefrontal cerebral blood flow, cognitive performance, and psychological factors. Additionally, the moderating and mediating effects of arterial stiffness on changes in cerebral blood flow will be tested.

Methods

This is a protocol for a randomized crossover study that will recruit 16 adolescents (13–14 years old). Participants will undergo three different conditions in a randomized order, on three separate days, involving sitting 80 min with a different type of break every 17 min for 3 min. The breaks will consist of (1) seated social breaks, (2) simple resistance activities, and (3) step-up activities. Before and after the 80-min conditions, prefrontal cerebral blood flow changes will be measured using functional near-infrared spectroscopy (primary outcome), while performing working memory tasks (1-, 2-, and 3-back tests). Arterial stiffness (augmentation index and pulse wave velocity) and psychological factors will also be assessed pre and post the 80-min interventions.

Discussion

Publication of this protocol will help to increase rigor in science. The results will inform regarding the underlying mechanisms driving the association between physical activity breaks and cognitive performance. This information can be used for designing effective and feasible interventions to be implemented in schools.

Trial registration

www.ClinicalTrials.gov, NCT04552626. Retrospectively registered on September 21, 2020.

Available only for authorised users

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Title: ABBaH teens: Activity Breaks for Brain Health in adolescents: study protocol for a randomized crossover trial
Authors: Emerald G. Heiland
Karin Kjellenberg
Olga Tarassova
Maria Fernström
Gisela Nyberg
Maria M. Ekblom
Björg Helgadottir
Örjan Ekblom
Publication date: 01-12-2022
Publisher: BioMed Central
Published in: Trials / Issue 1/2022
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/s13063-021-05972-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

ABBaH teens: Activity Breaks for Brain Health in adolescents: study protocol for a randomized crossover trial

Abstract

Background

Methods

Discussion

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Discussion

Trial registration

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