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Published in: Abdominal Radiology 3/2018

01-03-2018 | Pictorial essay

A systematic approach to adnexal masses discovered on ultrasound: the ADNEx MR scoring system

Authors: Elizabeth A. Sadowski, Jessica B. Robbins, Andrea G. Rockall, Isabelle Thomassin-Naggara

Published in: Abdominal Radiology | Issue 3/2018

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Abstract

Adnexal lesions are a common occurrence in radiology practice and imaging plays a crucial role in triaging women appropriately. Current trends toward early detection and characterization have increased the need for accurate imaging assessment of adnexal lesions prior to treatment. Ultrasound is the first-line imaging modality for assessing adnexal lesions; however, approximately 20% of lesions are incompletely characterized after ultrasound evaluation. Secondary assessment with MR imaging using the ADNEx MR Scoring System has been demonstrated as highly accurate in the characterization of adnexal lesions and in excluding ovarian cancer. This review will address the role of MR imaging in further assessment of adnexal lesions discovered on US, and the utility of the ADNEx MR Scoring System.
Literature
1.
go back to reference Fishman DA, Cohen L, Blank SV, et al. (2005) The role of ultrasound evaluation in the detection of early-stage epithelial ovarian cancer. Am J Obstet Gynecol 192:1214–1221 (discussion 1221-1212)CrossRefPubMed Fishman DA, Cohen L, Blank SV, et al. (2005) The role of ultrasound evaluation in the detection of early-stage epithelial ovarian cancer. Am J Obstet Gynecol 192:1214–1221 (discussion 1221-1212)CrossRefPubMed
2.
go back to reference Sharma A, Apostolidou S, Burnell M, et al. (2012) Risk of epithelial ovarian cancer in asymptomatic women with ultrasound-detected ovarian masses: a prospective cohort study within the UK collaborative trial of ovarian cancer screening (UKCTOCS). Ultrasound Obstet Gynecol 40:338–344CrossRefPubMed Sharma A, Apostolidou S, Burnell M, et al. (2012) Risk of epithelial ovarian cancer in asymptomatic women with ultrasound-detected ovarian masses: a prospective cohort study within the UK collaborative trial of ovarian cancer screening (UKCTOCS). Ultrasound Obstet Gynecol 40:338–344CrossRefPubMed
3.
go back to reference Stukan M, Dudziak M, Ratajczak K, Grabowski JP (2015) Usefulness of diagnostic indices comprising clinical, sonographic, and biomarker data for discriminating benign from malignant ovarian masses. J Ultrasound Med 34:207–217CrossRefPubMed Stukan M, Dudziak M, Ratajczak K, Grabowski JP (2015) Usefulness of diagnostic indices comprising clinical, sonographic, and biomarker data for discriminating benign from malignant ovarian masses. J Ultrasound Med 34:207–217CrossRefPubMed
4.
go back to reference Timmerman D, Ameye L, Fischerova D, et al. (2010) Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ 341:c6839CrossRefPubMedPubMedCentral Timmerman D, Ameye L, Fischerova D, et al. (2010) Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ 341:c6839CrossRefPubMedPubMedCentral
5.
go back to reference Cadron I, Leunen K, Van Gorp T, et al. (2007) Management of borderline ovarian neoplasms. J Clin Oncol 25:2928–2937CrossRefPubMed Cadron I, Leunen K, Van Gorp T, et al. (2007) Management of borderline ovarian neoplasms. J Clin Oncol 25:2928–2937CrossRefPubMed
6.
go back to reference Darai E, Fauvet R, Uzan C, et al. (2013) Fertility and borderline ovarian tumor: a systematic review of conservative management, risk of recurrence and alternative options. Hum Reprod Update 19:151–166CrossRefPubMed Darai E, Fauvet R, Uzan C, et al. (2013) Fertility and borderline ovarian tumor: a systematic review of conservative management, risk of recurrence and alternative options. Hum Reprod Update 19:151–166CrossRefPubMed
7.
go back to reference Tinelli R, Tinelli A, Tinelli FG, Cicinelli E, Malvasi A (2006) Conservative surgery for borderline ovarian tumors: a review. Gynecol Oncol 100:185–191CrossRefPubMed Tinelli R, Tinelli A, Tinelli FG, Cicinelli E, Malvasi A (2006) Conservative surgery for borderline ovarian tumors: a review. Gynecol Oncol 100:185–191CrossRefPubMed
8.
go back to reference Medeiros LR, Freitas LB, Rosa DD, et al. (2011) Accuracy of magnetic resonance imaging in ovarian tumor: a systematic quantitative review. Am J Obstet Gynecol 204:67.e61-10CrossRef Medeiros LR, Freitas LB, Rosa DD, et al. (2011) Accuracy of magnetic resonance imaging in ovarian tumor: a systematic quantitative review. Am J Obstet Gynecol 204:67.e61-10CrossRef
9.
go back to reference Mohaghegh P, Rockall AG (2012) Imaging strategy for early ovarian cancer: characterization of adnexal masses with conventional and advanced imaging techniques. Radiographics 32:1751–1773CrossRefPubMed Mohaghegh P, Rockall AG (2012) Imaging strategy for early ovarian cancer: characterization of adnexal masses with conventional and advanced imaging techniques. Radiographics 32:1751–1773CrossRefPubMed
10.
go back to reference Sayasneh A, Ekechi C, Ferrara L, et al. (2015) The characteristic ultrasound features of specific types of ovarian pathology (review). Int J Oncol 46:445–458CrossRefPubMed Sayasneh A, Ekechi C, Ferrara L, et al. (2015) The characteristic ultrasound features of specific types of ovarian pathology (review). Int J Oncol 46:445–458CrossRefPubMed
11.
go back to reference Spencer JA, Ghattamaneni S (2010) MR imaging of the sonographically indeterminate adnexal mass. Radiology 256:677–694CrossRefPubMed Spencer JA, Ghattamaneni S (2010) MR imaging of the sonographically indeterminate adnexal mass. Radiology 256:677–694CrossRefPubMed
12.
go back to reference Braicu EI, Sehouli J, Richter R, et al. (2012) Primary versus secondary cytoreduction for epithelial ovarian cancer: a paired analysis of tumour pattern and surgical outcome. Eur J Cancer 48:687–694CrossRefPubMed Braicu EI, Sehouli J, Richter R, et al. (2012) Primary versus secondary cytoreduction for epithelial ovarian cancer: a paired analysis of tumour pattern and surgical outcome. Eur J Cancer 48:687–694CrossRefPubMed
13.
go back to reference Bristow RE, Chang J, Ziogas A, Anton-Culver H (2013) Adherence to treatment guidelines for ovarian cancer as a measure of quality care. Obstet Gynecol 121:1226–1234CrossRefPubMed Bristow RE, Chang J, Ziogas A, Anton-Culver H (2013) Adherence to treatment guidelines for ovarian cancer as a measure of quality care. Obstet Gynecol 121:1226–1234CrossRefPubMed
14.
go back to reference Earle CC, Schrag D, Neville BA, et al. (2006) Effect of surgeon specialty on processes of care and outcomes for ovarian cancer patients. J Natl Cancer Inst 98:172–180CrossRefPubMed Earle CC, Schrag D, Neville BA, et al. (2006) Effect of surgeon specialty on processes of care and outcomes for ovarian cancer patients. J Natl Cancer Inst 98:172–180CrossRefPubMed
15.
go back to reference Elattar A, Bryant A, Winter-Roach BA, Hatem M, Naik R (2011) Optimal primary surgical treatment for advanced epithelial ovarian cancer. Cochrane Database Syst Rev 8:Cd007565 Elattar A, Bryant A, Winter-Roach BA, Hatem M, Naik R (2011) Optimal primary surgical treatment for advanced epithelial ovarian cancer. Cochrane Database Syst Rev 8:Cd007565
16.
go back to reference Engelen MJ, Kos HE, Willemse PH, et al. (2006) Surgery by consultant gynecologic oncologists improves survival in patients with ovarian carcinoma. Cancer 106:589–598CrossRefPubMed Engelen MJ, Kos HE, Willemse PH, et al. (2006) Surgery by consultant gynecologic oncologists improves survival in patients with ovarian carcinoma. Cancer 106:589–598CrossRefPubMed
17.
go back to reference Woo YL, Kyrgiou M, Bryant A, Everett T, Dickinson HO (2012) Centralisation of services for gynaecological cancers: a Cochrane systematic review. Gynecol Oncol 126:286–290CrossRefPubMed Woo YL, Kyrgiou M, Bryant A, Everett T, Dickinson HO (2012) Centralisation of services for gynaecological cancers: a Cochrane systematic review. Gynecol Oncol 126:286–290CrossRefPubMed
18.
go back to reference Vergote I, De Brabanter J, Fyles A, et al. (2001) Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma. Lancet 357:176–182CrossRefPubMed Vergote I, De Brabanter J, Fyles A, et al. (2001) Prognostic importance of degree of differentiation and cyst rupture in stage I invasive epithelial ovarian carcinoma. Lancet 357:176–182CrossRefPubMed
19.
go back to reference Brown DL, Doubilet PM, Miller FH, et al. (1998) Benign and malignant ovarian masses: selection of the most discriminating gray-scale and Doppler sonographic features. Radiology 208:103–110CrossRefPubMed Brown DL, Doubilet PM, Miller FH, et al. (1998) Benign and malignant ovarian masses: selection of the most discriminating gray-scale and Doppler sonographic features. Radiology 208:103–110CrossRefPubMed
20.
go back to reference Buys SS, Partridge E, Greene MH, et al. (2005) Ovarian cancer screening in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial: findings from the initial screen of a randomized trial. Am J Obstet Gynecol 193:1630–1639CrossRefPubMed Buys SS, Partridge E, Greene MH, et al. (2005) Ovarian cancer screening in the prostate, lung, colorectal and ovarian (PLCO) cancer screening trial: findings from the initial screen of a randomized trial. Am J Obstet Gynecol 193:1630–1639CrossRefPubMed
21.
go back to reference Castillo G, Alcazar JL, Jurado M (2004) Natural history of sonographically detected simple unilocular adnexal cysts in asymptomatic postmenopausal women. Gynecol Oncol 92:965–969CrossRefPubMed Castillo G, Alcazar JL, Jurado M (2004) Natural history of sonographically detected simple unilocular adnexal cysts in asymptomatic postmenopausal women. Gynecol Oncol 92:965–969CrossRefPubMed
22.
go back to reference Ekerhovd E, Wienerroith H, Staudach A, Granberg S (2001) Preoperative assessment of unilocular adnexal cysts by transvaginal ultrasonography: a comparison between ultrasonographic morphologic imaging and histopathologic diagnosis. Am J Obstet Gynecol 184:48–54CrossRefPubMed Ekerhovd E, Wienerroith H, Staudach A, Granberg S (2001) Preoperative assessment of unilocular adnexal cysts by transvaginal ultrasonography: a comparison between ultrasonographic morphologic imaging and histopathologic diagnosis. Am J Obstet Gynecol 184:48–54CrossRefPubMed
23.
go back to reference Greenlee RT, Kessel B, Williams CR, et al. (2010) Prevalence, incidence, and natural history of simple ovarian cysts among women >55 years old in a large cancer screening trial. Am J Obstet Gynecol 202(373):e371–e379 Greenlee RT, Kessel B, Williams CR, et al. (2010) Prevalence, incidence, and natural history of simple ovarian cysts among women >55 years old in a large cancer screening trial. Am J Obstet Gynecol 202(373):e371–e379
24.
go back to reference Levine D, Gosink BB, Wolf SI, Feldesman MR, Pretorius DH (1992) Simple adnexal cysts: the natural history in postmenopausal women. Radiology 184:653–659CrossRefPubMed Levine D, Gosink BB, Wolf SI, Feldesman MR, Pretorius DH (1992) Simple adnexal cysts: the natural history in postmenopausal women. Radiology 184:653–659CrossRefPubMed
25.
go back to reference Modesitt SC, Pavlik EJ, Ueland FR, et al. (2003) Risk of malignancy in unilocular ovarian cystic tumors less than 10 centimeters in diameter. Obst Gynecol 102:594–599 Modesitt SC, Pavlik EJ, Ueland FR, et al. (2003) Risk of malignancy in unilocular ovarian cystic tumors less than 10 centimeters in diameter. Obst Gynecol 102:594–599
26.
go back to reference Timor-Tritsch IE, Goldstein SR (2005) The complexity of a “complex mass” and the simplicity of a “simple cyst”. J Ultrasound Med 24:255–258CrossRefPubMed Timor-Tritsch IE, Goldstein SR (2005) The complexity of a “complex mass” and the simplicity of a “simple cyst”. J Ultrasound Med 24:255–258CrossRefPubMed
27.
go back to reference Valentin L, Ameye L, Franchi D, et al. (2013) Risk of malignancy in unilocular cysts: a study of 1148 adnexal masses classified as unilocular cysts at transvaginal ultrasound and review of the literature. Ultrasound Obstet Gynecol 41:80–89CrossRefPubMed Valentin L, Ameye L, Franchi D, et al. (2013) Risk of malignancy in unilocular cysts: a study of 1148 adnexal masses classified as unilocular cysts at transvaginal ultrasound and review of the literature. Ultrasound Obstet Gynecol 41:80–89CrossRefPubMed
28.
go back to reference Thomassin-Naggara I, Aubert E, Rockall A, et al. (2013) Adnexal masses: development and preliminary validation of an MR imaging scoring system. Radiology 267:432–443CrossRefPubMed Thomassin-Naggara I, Aubert E, Rockall A, et al. (2013) Adnexal masses: development and preliminary validation of an MR imaging scoring system. Radiology 267:432–443CrossRefPubMed
29.
go back to reference Hricak H, Chen M, Coakley FV, et al. (2000) Complex adnexal masses: detection and characterization with MR imaging–multivariate analysis. Radiology 214:39–46CrossRefPubMed Hricak H, Chen M, Coakley FV, et al. (2000) Complex adnexal masses: detection and characterization with MR imaging–multivariate analysis. Radiology 214:39–46CrossRefPubMed
30.
go back to reference Sohaib SA, Mills TD, Sahdev A, et al. (2005) The role of magnetic resonance imaging and ultrasound in patients with adnexal masses. Clin Radiol 60:340–348CrossRefPubMed Sohaib SA, Mills TD, Sahdev A, et al. (2005) The role of magnetic resonance imaging and ultrasound in patients with adnexal masses. Clin Radiol 60:340–348CrossRefPubMed
31.
go back to reference Sohaib SA, Sahdev A, Van Trappen P, Jacobs IJ, Reznek RH (2003) Characterization of adnexal mass lesions on MR imaging. Am J Roentgenol 180:1297–1304CrossRef Sohaib SA, Sahdev A, Van Trappen P, Jacobs IJ, Reznek RH (2003) Characterization of adnexal mass lesions on MR imaging. Am J Roentgenol 180:1297–1304CrossRef
35.
36.
go back to reference Salvador S, Gilks B, Kobel M, et al. (2009) The fallopian tube: primary site of most pelvic high-grade serous carcinomas. Int J Gynecol Cancer 19:58–64CrossRefPubMed Salvador S, Gilks B, Kobel M, et al. (2009) The fallopian tube: primary site of most pelvic high-grade serous carcinomas. Int J Gynecol Cancer 19:58–64CrossRefPubMed
37.
go back to reference Munksgaard PS, Blaakaer J (2011) The association between endometriosis and gynecological cancers and breast cancer: a review of epidemiological data. Gynecol Oncol 123:157–163CrossRefPubMed Munksgaard PS, Blaakaer J (2011) The association between endometriosis and gynecological cancers and breast cancer: a review of epidemiological data. Gynecol Oncol 123:157–163CrossRefPubMed
38.
go back to reference Berns EM, Bowtell DD (2012) The changing view of high-grade serous ovarian cancer. Cancer Res 72:2701–2704CrossRefPubMed Berns EM, Bowtell DD (2012) The changing view of high-grade serous ovarian cancer. Cancer Res 72:2701–2704CrossRefPubMed
39.
go back to reference Meinhold-Heerlein I, Fotopoulou C, Harter P, et al. (2016) The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications. Arch Gynecol Obstet 293:695–700CrossRefPubMed Meinhold-Heerlein I, Fotopoulou C, Harter P, et al. (2016) The new WHO classification of ovarian, fallopian tube, and primary peritoneal cancer and its clinical implications. Arch Gynecol Obstet 293:695–700CrossRefPubMed
40.
go back to reference Kaijser J, Vandecaveye V, Deroose CM, et al. (2014) Imaging techniques for the pre-surgical diagnosis of adnexal tumours. Best Pract Res Clin Obstet Gynaecol 28:683–695CrossRefPubMed Kaijser J, Vandecaveye V, Deroose CM, et al. (2014) Imaging techniques for the pre-surgical diagnosis of adnexal tumours. Best Pract Res Clin Obstet Gynaecol 28:683–695CrossRefPubMed
41.
go back to reference Shim SH, Kim SN, Jung PS, et al. (2016) Impact of surgical staging on prognosis in patients with borderline ovarian tumours: a meta-analysis. Eur J Cancer 54:84–95CrossRefPubMed Shim SH, Kim SN, Jung PS, et al. (2016) Impact of surgical staging on prognosis in patients with borderline ovarian tumours: a meta-analysis. Eur J Cancer 54:84–95CrossRefPubMed
42.
go back to reference Anthoulakis C, Nikoloudis N (2014) Pelvic MRI as the “gold standard” in the subsequent evaluation of ultrasound-indeterminate adnexal lesions: a systematic review. Gynecol Oncol 132:661–668CrossRefPubMed Anthoulakis C, Nikoloudis N (2014) Pelvic MRI as the “gold standard” in the subsequent evaluation of ultrasound-indeterminate adnexal lesions: a systematic review. Gynecol Oncol 132:661–668CrossRefPubMed
43.
go back to reference Van Calster B, Van Hoorde K, Valentin L, et al. (2014) Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study. BMJ 349:g5920CrossRefPubMedPubMedCentral Van Calster B, Van Hoorde K, Valentin L, et al. (2014) Evaluating the risk of ovarian cancer before surgery using the ADNEX model to differentiate between benign, borderline, early and advanced stage invasive, and secondary metastatic tumours: prospective multicentre diagnostic study. BMJ 349:g5920CrossRefPubMedPubMedCentral
44.
go back to reference Brun JL, Fritel X, Aubard Y, et al. (2014) Management of presumed benign ovarian tumors: updated French guidelines. Eur J Obstet Gynecol Reprod Biol 183:52–58CrossRefPubMed Brun JL, Fritel X, Aubard Y, et al. (2014) Management of presumed benign ovarian tumors: updated French guidelines. Eur J Obstet Gynecol Reprod Biol 183:52–58CrossRefPubMed
45.
go back to reference Guerriero S, Alcazar JL, Coccia ME, et al. (2002) Complex pelvic mass as a target of evaluation of vessel distribution by color Doppler sonography for the diagnosis of adnexal malignancies: results of a multicenter European study. J Ultrasound Med 21:1105–1111CrossRefPubMed Guerriero S, Alcazar JL, Coccia ME, et al. (2002) Complex pelvic mass as a target of evaluation of vessel distribution by color Doppler sonography for the diagnosis of adnexal malignancies: results of a multicenter European study. J Ultrasound Med 21:1105–1111CrossRefPubMed
46.
go back to reference Valentin L (1999) Prospective cross-validation of Doppler ultrasound examination and gray-scale ultrasound imaging for discrimination of benign and malignant pelvic masses. Ultrasound Obstet Gynecol 14:273–283CrossRefPubMed Valentin L (1999) Prospective cross-validation of Doppler ultrasound examination and gray-scale ultrasound imaging for discrimination of benign and malignant pelvic masses. Ultrasound Obstet Gynecol 14:273–283CrossRefPubMed
47.
go back to reference Stein SM, Laifer-Narin S, Johnson MB, et al. (1995) Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography. Am J Roentgenol 164:381–386CrossRef Stein SM, Laifer-Narin S, Johnson MB, et al. (1995) Differentiation of benign and malignant adnexal masses: relative value of gray-scale, color Doppler, and spectral Doppler sonography. Am J Roentgenol 164:381–386CrossRef
48.
go back to reference Buy JN, Ghossain MA, Hugol D, et al. (1996) Characterization of adnexal masses: combination of color Doppler and conventional sonography compared with spectral Doppler analysis alone and conventional sonography alone. Am J Roentgenol 166:385–393CrossRef Buy JN, Ghossain MA, Hugol D, et al. (1996) Characterization of adnexal masses: combination of color Doppler and conventional sonography compared with spectral Doppler analysis alone and conventional sonography alone. Am J Roentgenol 166:385–393CrossRef
49.
go back to reference Medeiros LR, Rosa DD, da Rosa MI, Bozzetti MC (2009) Accuracy of ultrasonography with color Doppler in ovarian tumor: a systematic quantitative review. Int J Gynecol Cancer 19:1214–1220CrossRefPubMed Medeiros LR, Rosa DD, da Rosa MI, Bozzetti MC (2009) Accuracy of ultrasonography with color Doppler in ovarian tumor: a systematic quantitative review. Int J Gynecol Cancer 19:1214–1220CrossRefPubMed
50.
go back to reference Sokalska A, Timmerman D, Testa AC, et al. (2009) Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses. Ultrasound Obstet Gynecol 34:462–470CrossRefPubMed Sokalska A, Timmerman D, Testa AC, et al. (2009) Diagnostic accuracy of transvaginal ultrasound examination for assigning a specific diagnosis to adnexal masses. Ultrasound Obstet Gynecol 34:462–470CrossRefPubMed
51.
go back to reference Levine D, Brown DL, Andreotti RF, et al. (2010) Management of asymptomatic ovarian and other adnexal cysts imaged at US Society of Radiologists in Ultrasound consensus conference statement. Ultrasound Q 26:121–131CrossRefPubMed Levine D, Brown DL, Andreotti RF, et al. (2010) Management of asymptomatic ovarian and other adnexal cysts imaged at US Society of Radiologists in Ultrasound consensus conference statement. Ultrasound Q 26:121–131CrossRefPubMed
52.
go back to reference Siegelman ES, Outwater EK (1999) Tissue characterization in the female pelvis by means of MR imaging. Radiology 212:5–18CrossRefPubMed Siegelman ES, Outwater EK (1999) Tissue characterization in the female pelvis by means of MR imaging. Radiology 212:5–18CrossRefPubMed
53.
go back to reference Adusumilli S, Hussain HK, Caoili EM, et al. (2006) MRI of sonographically indeterminate adnexal masses. Am J Roentgenol 187:732–740CrossRef Adusumilli S, Hussain HK, Caoili EM, et al. (2006) MRI of sonographically indeterminate adnexal masses. Am J Roentgenol 187:732–740CrossRef
54.
go back to reference Tsili AC, Tsampoulas C, Argyropoulou M, et al. (2008) Comparative evaluation of multidetector CT and MR imaging in the differentiation of adnexal masses. Eur Radiol 18:1049–1057CrossRefPubMed Tsili AC, Tsampoulas C, Argyropoulou M, et al. (2008) Comparative evaluation of multidetector CT and MR imaging in the differentiation of adnexal masses. Eur Radiol 18:1049–1057CrossRefPubMed
55.
go back to reference Takeuchi M, Matsuzaki K, Nishitani H (2010) Diffusion-weighted magnetic resonance imaging of ovarian tumors: differentiation of benign and malignant solid components of ovarian masses. J Comput Assist Tomogr 34:173–176CrossRefPubMed Takeuchi M, Matsuzaki K, Nishitani H (2010) Diffusion-weighted magnetic resonance imaging of ovarian tumors: differentiation of benign and malignant solid components of ovarian masses. J Comput Assist Tomogr 34:173–176CrossRefPubMed
56.
go back to reference Thomassin-Naggara I, Balvay D, Aubert E, et al. (2012) Quantitative dynamic contrast-enhanced MR imaging analysis of complex adnexal masses: a preliminary study. Eur Radiol 22:738–745CrossRefPubMed Thomassin-Naggara I, Balvay D, Aubert E, et al. (2012) Quantitative dynamic contrast-enhanced MR imaging analysis of complex adnexal masses: a preliminary study. Eur Radiol 22:738–745CrossRefPubMed
57.
go back to reference Thomassin-Naggara I, Bazot M, Darai E, et al. (2008) Epithelial ovarian tumors: value of dynamic contrast-enhanced MR imaging and correlation with tumor angiogenesis. Radiology 248:148–159CrossRefPubMed Thomassin-Naggara I, Bazot M, Darai E, et al. (2008) Epithelial ovarian tumors: value of dynamic contrast-enhanced MR imaging and correlation with tumor angiogenesis. Radiology 248:148–159CrossRefPubMed
58.
go back to reference Thomassin-Naggara I, Toussaint I, Perrot N, et al. (2011) Characterization of complex adnexal masses: value of adding perfusion- and diffusion-weighted MR imaging to conventional MR imaging. Radiology 258:793–803CrossRefPubMed Thomassin-Naggara I, Toussaint I, Perrot N, et al. (2011) Characterization of complex adnexal masses: value of adding perfusion- and diffusion-weighted MR imaging to conventional MR imaging. Radiology 258:793–803CrossRefPubMed
59.
go back to reference Spencer JA, Forstner R, Cunha TM, Kinkel K (2010) ESUR guidelines for MR imaging of the sonographically indeterminate adnexal mass: an algorithmic approach. Eur Radiol 20:25–35CrossRefPubMed Spencer JA, Forstner R, Cunha TM, Kinkel K (2010) ESUR guidelines for MR imaging of the sonographically indeterminate adnexal mass: an algorithmic approach. Eur Radiol 20:25–35CrossRefPubMed
60.
go back to reference Timmerman D, Valentin L, Bourne TH, et al. (2000) Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) Group. Ultrasound Obstet Gynecol 16:500–505CrossRefPubMed Timmerman D, Valentin L, Bourne TH, et al. (2000) Terms, definitions and measurements to describe the sonographic features of adnexal tumors: a consensus opinion from the International Ovarian Tumor Analysis (IOTA) Group. Ultrasound Obstet Gynecol 16:500–505CrossRefPubMed
61.
go back to reference Lalwani N, Prasad SR, Vikram R, et al. (2011) Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics 31:625–646CrossRefPubMed Lalwani N, Prasad SR, Vikram R, et al. (2011) Histologic, molecular, and cytogenetic features of ovarian cancers: implications for diagnosis and treatment. Radiographics 31:625–646CrossRefPubMed
62.
go back to reference Corwin MT, Gerscovich EO, Lamba R, Wilson M, McGahan JP (2014) Differentiation of ovarian endometriomas from hemorrhagic cysts at MR imaging: utility of the T2 dark spot sign. Radiology 271:126–132CrossRefPubMed Corwin MT, Gerscovich EO, Lamba R, Wilson M, McGahan JP (2014) Differentiation of ovarian endometriomas from hemorrhagic cysts at MR imaging: utility of the T2 dark spot sign. Radiology 271:126–132CrossRefPubMed
63.
go back to reference Bal A, Mohan H, Singh SB, Sehgal A (2007) Malignant transformation in mature cystic teratoma of the ovary: report of five cases and review of the literature. Arch Gynecol Obstet 275:179–182CrossRefPubMed Bal A, Mohan H, Singh SB, Sehgal A (2007) Malignant transformation in mature cystic teratoma of the ovary: report of five cases and review of the literature. Arch Gynecol Obstet 275:179–182CrossRefPubMed
64.
go back to reference Khashper A, Addley HC, Abourokbah N, et al. (2012) T2-hypointense adnexal lesions: an imaging algorithm. Radiographics 32:1047–1064CrossRefPubMed Khashper A, Addley HC, Abourokbah N, et al. (2012) T2-hypointense adnexal lesions: an imaging algorithm. Radiographics 32:1047–1064CrossRefPubMed
65.
go back to reference Montoriol PF, Mons A, Da Ines D, et al. (2013) Fibrous tumours of the ovary: aetiologies and MRI features. Clin Radiol 68:1276–1283CrossRefPubMed Montoriol PF, Mons A, Da Ines D, et al. (2013) Fibrous tumours of the ovary: aetiologies and MRI features. Clin Radiol 68:1276–1283CrossRefPubMed
Metadata
Title
A systematic approach to adnexal masses discovered on ultrasound: the ADNEx MR scoring system
Authors
Elizabeth A. Sadowski
Jessica B. Robbins
Andrea G. Rockall
Isabelle Thomassin-Naggara
Publication date
01-03-2018
Publisher
Springer US
Published in
Abdominal Radiology / Issue 3/2018
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-017-1272-7

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