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Open Access 01-12-2013 | Case report

A rare case of bilateral sequential spermatocytic seminoma

Authors: Ning Xu, Fubiao Li, Runhui Tian, Mingming Shao, Lingyun Liu, Kaimin Guo

Published in: World Journal of Surgical Oncology | Issue 1/2013

Abstract

Spermatocytic seminoma (SS) is a rare testicular neoplasm characterized by a palpable, painless, slowly enlarging mass in the testis. Even more rare is a synchronous bilateral presentation. Only eight cases of bilateral SS have been reported in the literature, of which three cases were present with synchronous testis enlargement, and five were sequential. Here, we report an additional case of synchronous bilateral SS and present a comprehensive relevant literature review concerning clinical features, histopathology, and treatment.

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Talerman A: Spermatocytic seminoma: clinicopathological study of 22 cases. Cancer. 1980, 15: 2169-2176.CrossRef

Rosai J, Nochomovitz LE: Current concepts of the histogenesis, pathology, and immunocytochemistry of germ cell tumors of the testis. Parhol Annu. 1978, 13: 335-338.

Floyd C, Ayala AG, Logothetis CJ, Silva EG: Spermatocytic seminoma with associated sarcoma of the testis. Cancer. 1988, 15: 409-414.CrossRef

Rosai J, Silber I, Khodadoust K: Spermatocytic seminoma: clinicopathologic study of six cases and review of the literature. Cancer. 1969, 24: 92-102. 10.1002/1097-0142(196907)24:1<92::AID-CNCR2820240113>3.0.CO;2-E.CrossRefPubMed

Carrière P, Baade P, Fritschi L: Population based incidence and age distribution of spermatocytic seminoma. J Urol. 2007, 178: 125-128. 10.1016/j.juro.2007.03.024.CrossRefPubMed

Masson P: A study of seminomas. Rev Cunud B id. 1946, 5: 361-387.

Dundr P, Pesl M, Povýsil C, Prokopová P, Pavlík I, Soukup V, Dvorácek J: Anaplastic variant of spermatocytic seminoma. Pathol Res Pract. 2007, 203: 621-624. 10.1016/j.prp.2007.04.011.CrossRefPubMed

Chelly I, Mekni A, Gargouri MM, Bellil K, Zitouna M, Horchani A, Kchir N: Spermatocytic seminoma with rhabdomyosarcomatous contigent. Prog Urol. 2006, 16: 218-220.PubMed

Burke AP, Mostofi FK: Spermatocytic seminoma: a clinicopathologic study of 79 cases. J Urol Pathol. 1993, 1: 21-32.

10.

Chung PW, Bayley AJ, Sweet J, Jewett MA, Tew-George B, Gospodarowicz MK, Warde PR: Spermatocytic seminoma: a review. Eur Urol. 2004, 45: 495-498. 10.1016/j.eururo.2003.11.005.CrossRefPubMed

11.

Raiss GG, Benatiya Andaloussi MM, Raissouni SS, Mrabti HH, Errihani HH: Spermatocytic seminoma at the national institute of oncology in Morocco. BMC Res Notes. 2011, 29 (4): 218CrossRef

12.

Eble JN: Spermatocytic seminoma. Hum Pathol. 1994, 25: 1035-1042. 10.1016/0046-8177(94)90062-0.CrossRefPubMed

13.

Koppad SN, Sonawane SR, Kapoor VB, Deshmukh AM, Borole KA: Bilateral synchronous spermatocytic seminoma: a rare case report from rural India and literature review. Pan Afr Med J. 2012, 13: 34PubMedCentralPubMed

14.

Maruta S, Shida Y, Takehara K, Onita T, Igawa T, Sakai H: A case report of bilateral spermatocytic seminoma. Hinyokika Kiyo. 2011, 57: 525-528.PubMed

15.

Leocádio DE, Stein BS: A case of synchronous bilateral spermatocytic seminoma. Urol Oncol. 2008, 26: 202-203. 10.1016/j.urolonc.2007.02.009.CrossRefPubMed

16.

Bergner DM, Duck GB, Rao M: Bilateral sequential spermatocytic seminoma. J Urol. 1980, 124: 565PubMed

17.

Stoop H, Van Gurp R, De Krijger R, Geurts Van Kessel A, Köberle B, Oosterhuis W, Looijenga L: Reactivity of germ cell maturation stage-specific markers in spermatocytic seminoma: diagnostic and etiological implications. Lab Invest. 2001, 81: 919-928. 10.1038/labinvest.3780302.CrossRefPubMed

18.

Looijenga LH, Hersmus R, Gillis AJ, Pfundt R, Stoop HJ, Van Gurp RJ, Veltman J, Beverloo HB, Van Drunen E, Van Kessel AG, Pera RR, Schneider DT, Summersgill B, Shipley J, McIntyre A, van der Spek P, Schoenmakers E, Oosterhuis JW: Genomic and expression profiling of human spermatocytic seminomas: primary spermatocyte as tumorigenic precursor and DMRT1 as candidate chromosome 9 gene. Cancer Res. 2006, 66: 290-302. 10.1158/0008-5472.CAN-05-2936.CrossRefPubMed

19.

Górecki T, Kaszuba B, Ostrowska M, Mazurczyk K, Spliter L: Giant spermatocytic seminoma with massive hemorrhage into accompanying hydrocele: case report. Int Urol Nephrol. 2005, 37: 529-531. 10.1007/s11255-005-2085-0.CrossRefPubMed

20.

Lombardi M, Valli M, Brisigotti M, Rosai J: Spermatocytic seminoma: review of the literature and description of a new case of the anaplastic variant. Int J Surg Pathol. 2011, 19: 5-10.PubMed

21.

Narang V, Gupta K, Gupta A, Kumar S: Rhabdomyosarcomatous differentiation in a spermatocytic seminoma with review of literature. Indian J Urol. 2012, 28: 430-433. 10.4103/0970-1591.105760.PubMedCentralCrossRefPubMed

22.

Matoska J, Talerman A: Spermatocytic seminoma associated with rhabdomyosarcoma. Am J Clin Pathol. 1990, 94: 89-95.PubMed

23.

Oosterhuis JW, Looijenga LH: Testicular germ-cell tumours in a broader perspective. Nat Rev Cancer. 2005, 5: 210-222. 10.1038/nrc1568.CrossRefPubMed

24.

Albores-Saavedra J, Huffman H, Alvarado-Cabrero I, Ayala AG: Anaplastic variant of spermatocytic seminoma. Hum Pathol. 1996, 27: 650-655. 10.1016/S0046-8177(96)90393-7.CrossRefPubMed

25.

Aggarwal N, Parwani AV: Spermatocytic seminoma. Arch Pathol Lab Med. 2009, 133: 1985-1988.PubMed

26.

Decaussin M, Borda A, Bouvier R, Ruffion A, David C, Agard C, Arcin F, Collet F, Berger N: Spermatocytic seminoma: a clinicopathological and immunohistochemical study of 7 cases. Ann Pathol. 2004, 24: 161-166.CrossRefPubMed

27.

Horn T, Schulz S, Maurer T, Gschwend JE, Kübler HR: Poor efficacy of BEP polychemotherapy in metastatic spermatocytic seminoma. Med Oncol. 2011, 28: S423-S425. 10.1007/s12032-010-9739-1.CrossRefPubMed

28.

Saran RK, Banerjee AK, Gupta SK, Rajwanshi A: Spermatocytic seminoma: a cytology and histology case report with review of the literature. Diagn Cytopathol. 1999, 20: 233-236. 10.1002/(SICI)1097-0339(199904)20:4<233::AID-DC10>3.0.CO;2-0.CrossRefPubMed

29.

López JI, Aranda FI: Fine needle aspiration cytology of spermatocytic seminoma: report of a case. Acta Cytol. 1989, 33: 627-630.PubMed

Title: A rare case of bilateral sequential spermatocytic seminoma
Authors: Ning Xu
Fubiao Li
Runhui Tian
Mingming Shao
Lingyun Liu
Kaimin Guo
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: World Journal of Surgical Oncology / Issue 1/2013
Electronic ISSN: 1477-7819
DOI: https://doi.org/10.1186/1477-7819-11-175

At a glance: The STEP trials

Springer Medicine

A rare case of bilateral sequential spermatocytic seminoma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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