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Published in: Acta Neurochirurgica 5/2016

01-05-2016 | Editorial (by Invitation)

A quest towards personalised medicine for grade II meningiomas—will need to zoom in

Authors: Thomas Santarius, Michael D. Jenkinson, Ramez W. Kirollos

Published in: Acta Neurochirurgica | Issue 5/2016

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Excerpt

Champeaux and Dunn [2] have analysed the outcomes of grade II meningiomas (atypical, clear cell and choroid) resected in the Southern General Hospital in Glasgow between January 2000 and August 2015. The authors first identified cases that were classified as grade 2 according to the classification used at the time of surgery. The histological reports (not the histological slides themselves) were carefully reviewed and cases from before 2007 were reclassified according to the WHO 2007 classification of the tumours of the central nervous system [10] (further referred to as WHO 2007 classification). In the end, 206 cases were included in the study and only two patients were lost to follow-up. The median follow-up was 4.1 years, with the interquartile range of 1.6–7.3 years. …
Literature
1.
go back to reference Backer-Grøndahl T, Moen BH, Torp SH (2012) The histopathological spectrum of human meningiomas. Int J Clin Exp Pathol 5(3):231–242PubMedPubMedCentral Backer-Grøndahl T, Moen BH, Torp SH (2012) The histopathological spectrum of human meningiomas. Int J Clin Exp Pathol 5(3):231–242PubMedPubMedCentral
2.
go back to reference Champeaux C, Dunn L (2016) World Health Organization grade II meningiomas. A 10-year retrospective study on overall survival and associated prognostic factors. Acta Neurochir (Wein). doi:10.1007/s00701-016-2771-y Champeaux C, Dunn L (2016) World Health Organization grade II meningiomas. A 10-year retrospective study on overall survival and associated prognostic factors. Acta Neurochir (Wein). doi:10.​1007/​s00701-016-2771-y
3.
go back to reference Curtis C, Shah SP, Chin S-F et al (2012) The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486(7403):346–352PubMedPubMedCentral Curtis C, Shah SP, Chin S-F et al (2012) The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups. Nature 486(7403):346–352PubMedPubMedCentral
4.
go back to reference Gajjar A, Pfister SM, Taylor MD, Gilbertson RJ (2014) Molecular insights into pediatric brain tumors have the potential to transform therapy. Clin Cancer Res 20(22):5630–5640CrossRefPubMedPubMedCentral Gajjar A, Pfister SM, Taylor MD, Gilbertson RJ (2014) Molecular insights into pediatric brain tumors have the potential to transform therapy. Clin Cancer Res 20(22):5630–5640CrossRefPubMedPubMedCentral
5.
go back to reference Gousias K, Schramm J, Simon M (2016) The Simpson grading revisited: aggressive surgery and its place in modern meningioma management. J Neurosurg 1–10 Gousias K, Schramm J, Simon M (2016) The Simpson grading revisited: aggressive surgery and its place in modern meningioma management. J Neurosurg 1–10
6.
go back to reference Jenkinson MD, Javadpour M, Haylock BJ et al (2015) The ROAM/EORTC-1308 trial: radiation versus observation following surgical resection of atypical meningioma: study protocol for a randomised controlled trial. Trials 16:519CrossRefPubMedPubMedCentral Jenkinson MD, Javadpour M, Haylock BJ et al (2015) The ROAM/EORTC-1308 trial: radiation versus observation following surgical resection of atypical meningioma: study protocol for a randomised controlled trial. Trials 16:519CrossRefPubMedPubMedCentral
7.
go back to reference Kleihues P, Cavenee WK (2000) World Health Organization classification of tumours—pathology and genetics. Tumours of the nervous system. IARC Press, Lyon Kleihues P, Cavenee WK (2000) World Health Organization classification of tumours—pathology and genetics. Tumours of the nervous system. IARC Press, Lyon
8.
go back to reference Kleihues P, Burger PC, Scheithauer BW (1993) Histological typing of tumours of the central nevous system. Springer, BerlinCrossRef Kleihues P, Burger PC, Scheithauer BW (1993) Histological typing of tumours of the central nevous system. Springer, BerlinCrossRef
9.
go back to reference Kshettry VR, Ostrom QT, Kruchko C, Al-Mefty O, Barnett GH, Barnholtz-Sloan JS (2015) Descriptive epidemiology of World Health Organization grades II and III intracranial meningiomas in the United States. Neuro-Oncology 17(8):1166–1173CrossRefPubMed Kshettry VR, Ostrom QT, Kruchko C, Al-Mefty O, Barnett GH, Barnholtz-Sloan JS (2015) Descriptive epidemiology of World Health Organization grades II and III intracranial meningiomas in the United States. Neuro-Oncology 17(8):1166–1173CrossRefPubMed
10.
go back to reference Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) (2007) WHO classification of tumours of the central nervous system. IARC, Lyon Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) (2007) WHO classification of tumours of the central nervous system. IARC, Lyon
11.
go back to reference Marcus HJ, Price SJ, Wilby M, Santarius T, Kirollos RW (2008) Radiotherapy as an adjuvant in the management of intracranial meningiomas: are we practising evidence-based medicine? Br J Neurosurg 22(4):520–528CrossRefPubMed Marcus HJ, Price SJ, Wilby M, Santarius T, Kirollos RW (2008) Radiotherapy as an adjuvant in the management of intracranial meningiomas: are we practising evidence-based medicine? Br J Neurosurg 22(4):520–528CrossRefPubMed
12.
go back to reference Rogers L, Barani I, Chamberlain M, Kaley TJ, McDermott M, Raizer J, Schiff D, Weber DC, Wen PY, Vogelbaum MA (2014) Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 1–20 Rogers L, Barani I, Chamberlain M, Kaley TJ, McDermott M, Raizer J, Schiff D, Weber DC, Wen PY, Vogelbaum MA (2014) Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 1–20
14.
go back to reference Sughrue ME, Kane AJ, Shangari G, Rutkowski MJ, McDermott MW, Berger MS, Parsa AT (2010) The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas. J Neurosurg 113(5):1029–1035CrossRefPubMed Sughrue ME, Kane AJ, Shangari G, Rutkowski MJ, McDermott MW, Berger MS, Parsa AT (2010) The relevance of Simpson Grade I and II resection in modern neurosurgical treatment of World Health Organization Grade I meningiomas. J Neurosurg 113(5):1029–1035CrossRefPubMed
Metadata
Title
A quest towards personalised medicine for grade II meningiomas—will need to zoom in
Authors
Thomas Santarius
Michael D. Jenkinson
Ramez W. Kirollos
Publication date
01-05-2016
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 5/2016
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-016-2774-8

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