Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Trials
Published in: Trials 1/2013

Open Access 01-12-2013 | Study protocol

A pharmacist-led system-change smoking cessation intervention for smokers admitted to Australian public hospitals (GIVE UP FOR GOOD): study protocol for a randomised controlled trial

Authors: Dennis Thomas, Michael J Abramson, Billie Bonevski, Simone Taylor, Susan Poole, Gregory R Weeks, Michael J Dooley, Johnson George

Published in: Trials | Issue 1/2013

Login to get access

Abstract

Background

Intensive smoking cessation interventions initiated during hospitalisation are effective, but currently not widely available. Strategies are needed to integrate smoking cessation treatment into routine inpatient care. Pharmacist-led interventions for smoking cessation are feasible and efficacious in both ambulatory and community pharmacy settings. However, there is a lack of evidence from large scale studies of the effectiveness of pharmacist guided programs initiated during patient hospitalisation in achieving long-term abstinence. This study aims to evaluate the effectiveness of a pharmacist-led system change intervention initiated during hospitalisation in Australian public hospitals.

Methods/design

A multi-centre, randomised controlled trial will be conducted with 12 months follow-up. Smokers, 18 years or older, will be recruited from the wards of three Victorian public hospitals. Participants will be randomly assigned to a usual care or intervention group using a computer generated randomisation list. The intervention group will receive at least three smoking cessation support sessions by a trained pharmacist: the first during the hospital stay, the second on or immediately after discharge and the third within one month post-discharge. All smoking cessation medications will be provided free of charge during the hospital stay and for at least one week after discharge. Participants randomised to usual care will receive the current care routinely provided by the hospital. All measurements at baseline, discharge, one, six and 12 months will be performed by a blinded Research Assistant. The primary outcome measures are carbon monoxide validated 7-day point prevalence abstinence at six and 12 months.

Discussion

This is the first large scale study to develop and test a pharmacist-led system change intervention program initiated during patient hospitalisation. If successful, the program could be considered for wider implementation across other hospitals.

Trial registration

ACTRN12612000368​831
Appendix
Available only for authorised users
Literature
1.
World Health Organisation: WHO Report on the Global Tobacco Epidemic: Warning about the Dangers of Tobacco. 2011, Geneva: World Health Organisation
2.
Begg S, Vos T, Barker B, Stevenson C, Stanley L, Lopez AD: The Burden of Disease and Injury in Australia 2003. 2007, Canberra: Australian Institute of Health and Welfare
3.
Collins DJ, Lapsley HM: The Costs of Tobacco, Alcohol and Illicit Drug Abuse to Australian Society in 2004–05. 2008, Canberra: Department of Health and AgeingCrossRef
4.
Australian Institute of Health and Welfare: Australia’s Health 2012. The Thirteenth Biennial Health Report of the Australian Institute of Health and Welfare. 2012, Canberra: Australian Institute of Health and Welfare
5.
Bastian LA: Smoking cessation for hospital patients: an opportunity to increase the reach of effective smoking cessation programs. J Gen Intern Med. 2008, 23: 1286-1287. 10.1007/s11606-008-0703-0.CrossRefPubMedPubMedCentral
6.
McBride CM, Emmons KM, Lipkus IM: Understanding the potential of teachable moments: the case of smoking cessation. Health Educ Res. 2003, 18: 156-170. 10.1093/her/18.2.156.CrossRefPubMed
7.
Rosal MC, Ockene JK, Ma Y, Hebert JR, Ockene IS, Merriam P, Hurley TG: Coronary artery smoking intervention study (CASIS): 5-year follow-up. Health Psychol. 1998, 17: 476-478.CrossRefPubMed
8.
Sciamanna CN, Stillman FA, Hoch JS, Butler JH, Gass KG, Ford DE: Opportunities for improving inpatient smoking cessation programs: a community hospital experience. Prev Med. 2000, 30: 496-503. 10.1006/pmed.2000.0668.CrossRefPubMed
9.
Freund M, Campbell E, Paul C, Sakrouge R, Wiggers J: Smoking care provision in smoke-free hospitals in Australia. Prev Med. 2005, 41: 151-158. 10.1016/j.ypmed.2004.09.044.CrossRefPubMed
10.
Riley WT, Stevens VJ, Zhu SH, Morgan G, Grossman D: Overview of the consortium of hospitals advancing research on tobacco (chart). Trials. 2012, 13: 122-122. 10.1186/1745-6215-13-122.CrossRefPubMedPubMedCentral
11.
A clinical practice guideline for treating tobacco use and dependence: 2008 Update. A U.S. Public health service report. Am J Prev Med. 2008, 35: 158-176.CrossRef
12.
Ginn MB, Cox G, Heath J: Evidence-based approach to an inpatient tobacco cessation protocol. AACN Adv Crit Care. 2008, 19: 268-278. 10.1097/01.AACN.0000330377.49390.73.PubMed
13.
Rigotti NA, Clair C, Munafo MR, Stead LF: Interventions for smoking cessation in hospitalised patients. Cochrane Database Syst Rev. 2012, 5: CD001837
14.
Freund M, Campbell E, Paul C, Sakrouge R, McElduff P, Walsh RA, Wiggers J, Knight J, Girgis A: Increasing smoking cessation care provision in hospitals: a meta-analysis of intervention effect. Nicotine Tob Res. 2009, 11: 650-662. 10.1093/ntr/ntp056.CrossRefPubMed
15.
Freund M, Campbell E, Paul C, McElduff P, Walsh RA, Sakrouge R, Wiggers J, Knight J: Smoking care provision in hospitals: a review of prevalence. Nicotine Tob Res. 2008, 10: 757-774. 10.1080/14622200802027131.CrossRefPubMed
16.
George J, Taylor S, Hong T, Leung S, Nguyen J: A pilot study to investigate the scope for an in-patient smoking cessation program. Intern Med J. 2012, 42: e80-e83. 10.1111/j.1445-5994.2010.02287.x.CrossRefPubMed
17.
Wolfenden L, Wiggers J, Campbell E, Knight J, Kerridge R, Spigelman A: Providing comprehensive smoking cessation care to surgical patients: the case for computers. Drug Alcohol Rev. 2009, 28: 60-65. 10.1111/j.1465-3362.2008.00003.x.CrossRefPubMed
18.
Curry SJ: Organizational interventions to encourage guideline implementation. Chest. 2000, 118: 40S-46S. 10.1378/chest.118.2_suppl.40S.CrossRefPubMed
19.
Sinclair HK, Bond CM, Stead LF: Community pharmacy personnel interventions for smoking cessation. Cochrane Database Syst Rev. 2004, 1: CD003698
20.
Bock BC, Hudmon KS, Christian J, Graham AL, Bock FR: A tailored intervention to support pharmacy-based counseling for smoking cessation. Nicotine Tob Res. 2010, 12: 217-225. 10.1093/ntr/ntp197.CrossRefPubMedPubMedCentral
21.
Dent LA, Harris KJ, Noonan CW: Randomized trial assessing the effectiveness of a pharmacist-delivered program for smoking cessation. Ann Pharmacother. 2009, 43: 194-201.PubMed
22.
Dent LA, Harris KJ, Noonan CW: Tobacco interventions delivered by pharmacists: a summary and systematic review. Pharmacotherapy. 2007, 27: 1040-1051. 10.1592/phco.27.7.1040.CrossRefPubMed
23.
Borland R, Yong HH, O’Connor RJ, Hyland A, Thompson ME: The reliability and predictive validity of the Heaviness of Smoking Index and its two components: findings from the international tobacco control four country study. Nicotine Tob Res. 2010, 12 (Suppl): S45-S50.CrossRefPubMedPubMedCentral
24.
Fiore MC, Keller PA, Curry SJ: Health system changes to facilitate the delivery of tobacco-dependence treatment. Am J Prev Med. 2007, 33: S349-S356. 10.1016/j.amepre.2007.09.001.CrossRefPubMed
25.
26.
Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987, 40: 373-383. 10.1016/0021-9681(87)90171-8.CrossRefPubMed
27.
Kroenke K, Spitzer RL, Williams JBW: The patient health questionnaire-2: validity of a two-item depression screener. Med Care. 2003, 41: 1284-10.1097/01.MLR.0000093487.78664.3C.CrossRefPubMed
28.
Velicer WF, DiClemente CC, Rossi JS, Prochaska JO: Relapse situations and self-efficacy: an integrative model. Addict Behav. 1990, 15: 271-283. 10.1016/0306-4603(90)90070-E.CrossRefPubMed
29.
Niaura R, Shadel WG: Assessment to inform smoking cessation treatment. The Tobacco Dependence Treatment Handbook: A Guide to Best Practices. Edited by: Abrams DB, Niaura R, Brown RA, Emmons KM, Goldstein MG, Monti PM. 2003, New York: Guilford Press, 33-
30.
Ware JE, Kosinski M, Dewey JE, Gandek B: How to Score and Interpret Single-item Health Status Measures: A Manual for Users of the SF-8 Health Survey. 2001, Lincoln, RI: Quality Metric Inc.
31.
32.
West R, Hajek P, Stead L, Stapleton J: Outcome criteria in smoking cessation trials: proposal for a common standard. Addiction. 2005, 100: 299-303. 10.1111/j.1360-0443.2004.00995.x.CrossRefPubMed
33.
International Conference on Harmonisation of technical requirements for registration of pharmaceuticals for human use: Good Clinical Practice.http://​ichgcp.​net,
34.
35.
Metadata
Title
A pharmacist-led system-change smoking cessation intervention for smokers admitted to Australian public hospitals (GIVE UP FOR GOOD): study protocol for a randomised controlled trial
Authors
Dennis Thomas
Michael J Abramson
Billie Bonevski
Simone Taylor
Susan Poole
Gregory R Weeks
Michael J Dooley
Johnson George
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Trials / Issue 1/2013
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/1745-6215-14-148

Other articles of this Issue 1/2013

Trials 1/2013 Go to the issue

Study protocol

Effects of light-emitting diodes on muscle fatigue and exercise tolerance in patients with COPD: study protocol for a randomized controlled trial

Study protocol

Hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis (HERO): study protocol for a randomized controlled trial

Study protocol

Effects of an aquatic physical exercise program on glycemic control and perinatal outcomes of gestational diabetes: study protocol for a randomized controlled trial

Study protocol

Effect of intermediate care on mortality following emergency abdominal surgery. The InCare trial: study protocol, rationale and feasibility of a randomised multicentre trial

Study protocol

Evaluation of the Housing First program in patients with severe mental disorders in France: study protocol for a randomized controlled trial

Study protocol

Practical health co-operation - the impact of a referral template on quality of care and health care co-operation: study protocol for a cluster randomized controlled trial