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Published in: Surgical Endoscopy 1/2021

01-01-2021

A new platform for laparoscopic training: initial evaluation of the ex-vivo live multivisceral training device

Authors: Xiaobo Wang, Kunsong Zhang, Wenjie Hu, Ming Kuang, Serene Teo, Zhiyong Guo, Qiang Zhao, Xiaoshun He

Published in: Surgical Endoscopy | Issue 1/2021

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Abstract

Background

Various training models have been developed for laparoscopic training. Inanimate models including cadavers, ex-vivo simulator, and virtual reality (VR), are less realistic and often fail to display specific events such as bleeding, bile leakage, etc. Animal models provide more realistic experience, but constraints like cost involved, anesthetic requirement, and ethical approval have limited its application. We have designed a new training ex-vivo simulator—Smagister to address these issues.

Methods

The Smagister consists of a normothermic machine perfusion platform, multivisceral organ of porcine abdominal cavity (liver, gallbladder, pancreas, stomach, intestine, kidney, uterus, bladders, etc.), high-definition display, and software system. Blood gas analysis and number of peristalsis per hour were recorded. A questionnaire was used to subjectively assess vitality of the organ cluster every hour. Three laparoscopic procedures including cholecystectomy (LC), enterotomy closure (LEC) and hepatectomy (LLR) were performed on Smagister, with demonstration of specific events for each procedure. Six experts compared the procedures with actual surgery in terms of feasibility to complete procedures and demonstration of complications.

Results

The fluctuation of perfusate glucose (6.1–8.2 mmol/L) and lactate (5.82–6.55 mmol/L) suggested metabolic function of the multivisceral organs. The mean number of peristalsis was 2.2/min. The simulated surgical view and anatomic structures closely resembled actual surgery during continuous perfusion (3.5 ± 1.0, 3.8 ± 0.8, respectively). The evaluation scores of haptic feedbacks were 3.8 ± 0.8, resembling live tissue handling. LC, LEC, and LLR were performed well on the Smagister, with clear display of the specific events. All six experts considered Smagister as a suitable training modality for both basic and advanced laparoscopic surgery.

Conclusion

The amalgamation of live animal model and ex-vivo simulation in Smagister centralizes the virtue of both modalities, expands the training field, and provides high-fidelity laparoscopic training for both novice and senior surgeons.
Literature
1.
go back to reference Bang JY, Arnoletti JP, Holt BA, Sutton B, Hasan MK, Navaneethan U, Feranec N, Wilcox CM, Tharian B, Hawes RH, Varadarajulu S (2019) An endoscopic transluminal approach, compared with minimally invasive surgery, reduces complications and costs for patients with necrotizing pancreatitis. Gastroenterology 156:1027–1040.e1023CrossRef Bang JY, Arnoletti JP, Holt BA, Sutton B, Hasan MK, Navaneethan U, Feranec N, Wilcox CM, Tharian B, Hawes RH, Varadarajulu S (2019) An endoscopic transluminal approach, compared with minimally invasive surgery, reduces complications and costs for patients with necrotizing pancreatitis. Gastroenterology 156:1027–1040.e1023CrossRef
2.
go back to reference van Dijk AH, Wennmacker SZ, de Reuver PR, Latenstein CSS, Buyne O, Donkervoort SC, Eijsbouts QAJ, Heisterkamp J, Hof KI, Janssen J, Nieuwenhuijs VB, Schaap HM, Steenvoorde P, Stockmann H, Boerma D, Westert GP, Drenth JPH, Dijkgraaf MGW, Boermeester MA, van Laarhoven C (2019) Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial. Lancet (Lond, Engl) 393:2322–2330CrossRef van Dijk AH, Wennmacker SZ, de Reuver PR, Latenstein CSS, Buyne O, Donkervoort SC, Eijsbouts QAJ, Heisterkamp J, Hof KI, Janssen J, Nieuwenhuijs VB, Schaap HM, Steenvoorde P, Stockmann H, Boerma D, Westert GP, Drenth JPH, Dijkgraaf MGW, Boermeester MA, van Laarhoven C (2019) Restrictive strategy versus usual care for cholecystectomy in patients with gallstones and abdominal pain (SECURE): a multicentre, randomised, parallel-arm, non-inferiority trial. Lancet (Lond, Engl) 393:2322–2330CrossRef
3.
go back to reference Vennix S, Musters GD, Mulder IM, Swank HA, Consten EC, Belgers EH, van Geloven AA, Gerhards MF, Govaert MJ, van Grevenstein WM, Hoofwijk AG, Kruyt PM, Nienhuijs SW, Boermeester MA, Vermeulen J, van Dieren S, Lange JF, Bemelman WA (2015) Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet (Lond, Engl) 386:1269–1277CrossRef Vennix S, Musters GD, Mulder IM, Swank HA, Consten EC, Belgers EH, van Geloven AA, Gerhards MF, Govaert MJ, van Grevenstein WM, Hoofwijk AG, Kruyt PM, Nienhuijs SW, Boermeester MA, Vermeulen J, van Dieren S, Lange JF, Bemelman WA (2015) Laparoscopic peritoneal lavage or sigmoidectomy for perforated diverticulitis with purulent peritonitis: a multicentre, parallel-group, randomised, open-label trial. Lancet (Lond, Engl) 386:1269–1277CrossRef
4.
go back to reference Crothers IR, Gallagher AG, McClure N, James DT, McGuigan J (1999) Experienced laparoscopic surgeons are automated to the "fulcrum effect": an ergonomic demonstration. Endoscopy 31:365–369CrossRef Crothers IR, Gallagher AG, McClure N, James DT, McGuigan J (1999) Experienced laparoscopic surgeons are automated to the "fulcrum effect": an ergonomic demonstration. Endoscopy 31:365–369CrossRef
5.
go back to reference FuchsWeizman N, Maurer R, Einarsson JI, Vitonis AF, Cohen SL (2015) Survey on barriers to adoption of laparoscopic surgery. J surg educ 72:985–994CrossRef FuchsWeizman N, Maurer R, Einarsson JI, Vitonis AF, Cohen SL (2015) Survey on barriers to adoption of laparoscopic surgery. J surg educ 72:985–994CrossRef
6.
go back to reference Kassab E, Tun JK, Arora S, King D, Ahmed K, Miskovic D, Cope A, Vadhwana B, Bello F, Sevdalis N, Kneebone R (2011) "Blowing up the barriers" in surgical training: exploring and validating the concept of distributed simulation. Ann Surg 254:1059–1065CrossRef Kassab E, Tun JK, Arora S, King D, Ahmed K, Miskovic D, Cope A, Vadhwana B, Bello F, Sevdalis N, Kneebone R (2011) "Blowing up the barriers" in surgical training: exploring and validating the concept of distributed simulation. Ann Surg 254:1059–1065CrossRef
7.
go back to reference Mackenzie H, Cuming T, Miskovic D, Wyles SM, Langsford L, Anderson J, Thomas-Gibson S, Valori R, Hanna GB, Coleman MG, Francis N (2015) Design, delivery, and validation of a trainer curriculum for the national laparoscopic colorectal training program in England. Ann Surg 261:149–156CrossRef Mackenzie H, Cuming T, Miskovic D, Wyles SM, Langsford L, Anderson J, Thomas-Gibson S, Valori R, Hanna GB, Coleman MG, Francis N (2015) Design, delivery, and validation of a trainer curriculum for the national laparoscopic colorectal training program in England. Ann Surg 261:149–156CrossRef
8.
go back to reference Giger U, Fresard I, Hafliger A, Bergmann M, Krahenbuhl L (2008) Laparoscopic training on thiel human cadavers: a model to teach advanced laparoscopic procedures. Surg Endosc 22:901–906CrossRef Giger U, Fresard I, Hafliger A, Bergmann M, Krahenbuhl L (2008) Laparoscopic training on thiel human cadavers: a model to teach advanced laparoscopic procedures. Surg Endosc 22:901–906CrossRef
9.
go back to reference Wyles SM, Miskovic D, Ni Z, Acheson AG, Maxwell-Armstrong C, Longman R, Cecil T, Coleman MG, Horgan AF, Hanna GB (2011) Analysis of laboratory-based laparoscopic colorectal surgery workshops within the english national training programme. Surg Endosc 25:1559–1566CrossRef Wyles SM, Miskovic D, Ni Z, Acheson AG, Maxwell-Armstrong C, Longman R, Cecil T, Coleman MG, Horgan AF, Hanna GB (2011) Analysis of laboratory-based laparoscopic colorectal surgery workshops within the english national training programme. Surg Endosc 25:1559–1566CrossRef
10.
go back to reference LeBlanc F, Champagne BJ, Augestad KM, Neary PC, Senagore AJ, Ellis CN, Delaney CP (2010) A comparison of human cadaver and augmented reality simulator models for straight laparoscopic colorectal skills acquisition training. J Am Coll Surg 211:250–255CrossRef LeBlanc F, Champagne BJ, Augestad KM, Neary PC, Senagore AJ, Ellis CN, Delaney CP (2010) A comparison of human cadaver and augmented reality simulator models for straight laparoscopic colorectal skills acquisition training. J Am Coll Surg 211:250–255CrossRef
11.
go back to reference Cohen J, Cohen SA, Vora KC, Xue X, Burdick JS, Bank S, Bini EJ, Bodenheimer H, Cerulli M, Gerdes H, Greenwald D, Gress F, Grosman I, Hawes R, Mullin G, Schnoll-Sussman F, Starpoli A, Stevens P, Tenner S, Villanueva G (2006) Multicenter, randomized, controlled trial of virtual-reality simulator training in acquisition of competency in colonoscopy. Gastrointest Endosc 64:361–368CrossRef Cohen J, Cohen SA, Vora KC, Xue X, Burdick JS, Bank S, Bini EJ, Bodenheimer H, Cerulli M, Gerdes H, Greenwald D, Gress F, Grosman I, Hawes R, Mullin G, Schnoll-Sussman F, Starpoli A, Stevens P, Tenner S, Villanueva G (2006) Multicenter, randomized, controlled trial of virtual-reality simulator training in acquisition of competency in colonoscopy. Gastrointest Endosc 64:361–368CrossRef
12.
go back to reference Orzech N, Palter VN, Reznick RK, Aggarwal R, Grantcharov TP (2012) A comparison of 2 ex vivo training curricula for advanced laparoscopic skills: a randomized controlled trial. Ann Surg 255:833–839CrossRef Orzech N, Palter VN, Reznick RK, Aggarwal R, Grantcharov TP (2012) A comparison of 2 ex vivo training curricula for advanced laparoscopic skills: a randomized controlled trial. Ann Surg 255:833–839CrossRef
13.
go back to reference Gromski MA, Ahn W, Matthes K, De S (2016) Pre-clinical training for new notes procedures: from ex-vivo models to virtual reality simulators. Gastrointest Endosc Clin N Am 26:401–412CrossRef Gromski MA, Ahn W, Matthes K, De S (2016) Pre-clinical training for new notes procedures: from ex-vivo models to virtual reality simulators. Gastrointest Endosc Clin N Am 26:401–412CrossRef
14.
go back to reference Izawa Y, Hishikawa S, Muronoi T, Yamashita K, Maruyama H, Suzukawa M, Lefor AK (2016) Ex-vivo and live animal models are equally effective training for the management of a penetrating cardiac injury. World J Emerg Surg 11:45CrossRef Izawa Y, Hishikawa S, Muronoi T, Yamashita K, Maruyama H, Suzukawa M, Lefor AK (2016) Ex-vivo and live animal models are equally effective training for the management of a penetrating cardiac injury. World J Emerg Surg 11:45CrossRef
15.
go back to reference BeyerBerjot L, Palter V, Grantcharov T, Aggarwal R (2014) Advanced training in laparoscopic abdominal surgery: a systematic review. Surgery 156:676–688CrossRef BeyerBerjot L, Palter V, Grantcharov T, Aggarwal R (2014) Advanced training in laparoscopic abdominal surgery: a systematic review. Surgery 156:676–688CrossRef
16.
go back to reference Palter VN, Orzech N, Aggarwal R, Okrainec A, Grantcharov TP (2010) Resident perceptions of advanced laparoscopic skills training. Surg Endosc 24:2830–2834CrossRef Palter VN, Orzech N, Aggarwal R, Okrainec A, Grantcharov TP (2010) Resident perceptions of advanced laparoscopic skills training. Surg Endosc 24:2830–2834CrossRef
17.
go back to reference Blackburn SC, Griffin SJ (2014) Role of simulation in training the next generation of endoscopists. World J Gastrointest Endosc 6:234–239CrossRef Blackburn SC, Griffin SJ (2014) Role of simulation in training the next generation of endoscopists. World J Gastrointest Endosc 6:234–239CrossRef
18.
go back to reference Hammoud MM, Nuthalapaty FS, Goepfert AR, Casey PM, Emmons S, Espey EL, Kaczmarczyk JM, Katz NT, Neutens JJ, Peskin EG (2008) To the point: medical education review of the role of simulators in surgical training. Am J Obstet Gynecol 199:338–343CrossRef Hammoud MM, Nuthalapaty FS, Goepfert AR, Casey PM, Emmons S, Espey EL, Kaczmarczyk JM, Katz NT, Neutens JJ, Peskin EG (2008) To the point: medical education review of the role of simulators in surgical training. Am J Obstet Gynecol 199:338–343CrossRef
19.
go back to reference Russell WMS, Burch RL (1959) The principles of humane experimental technique. Methuen & Co Ltd, London Russell WMS, Burch RL (1959) The principles of humane experimental technique. Methuen & Co Ltd, London
20.
go back to reference Ceresa CDL, Nasralla D, Knight S, Friend PJ (2017) Cold storage or normothermic perfusion for liver transplantation: probable application and indications. Curr Opin Organ Transplant 22:300–305CrossRef Ceresa CDL, Nasralla D, Knight S, Friend PJ (2017) Cold storage or normothermic perfusion for liver transplantation: probable application and indications. Curr Opin Organ Transplant 22:300–305CrossRef
21.
go back to reference He X, Ji F, Zhang Z, Tang Y, Yang L, Huang S, Li W, Su Q, Xiong W, Zhu Z, Wang L, Lv L, Yao J, Zhang L, Zhang L, Guo Z (2018) Combined liver-kidney perfusion enhances protective effects of normothermic perfusion on liver grafts from donation after cardiac death. Liver Transplant 24:67–79CrossRef He X, Ji F, Zhang Z, Tang Y, Yang L, Huang S, Li W, Su Q, Xiong W, Zhu Z, Wang L, Lv L, Yao J, Zhang L, Zhang L, Guo Z (2018) Combined liver-kidney perfusion enhances protective effects of normothermic perfusion on liver grafts from donation after cardiac death. Liver Transplant 24:67–79CrossRef
22.
go back to reference Zhao Q, Huang S, Wang D, Zhang Z, Wu L, Yang L, Ma Y, Ji F, Tang Y, Wang L, Zhu Z, Zhu Y, Xiong W, Chen M, Han M, Zhou J, Hu A, Wang G, Jiao X, Zhu X, Ju W, Guo Z, He X (2018) Does ischemia free liver procurement under normothermic perfusion benefit the outcome of liver transplantation? Ann Transplant 23:258–267CrossRef Zhao Q, Huang S, Wang D, Zhang Z, Wu L, Yang L, Ma Y, Ji F, Tang Y, Wang L, Zhu Z, Zhu Y, Xiong W, Chen M, Han M, Zhou J, Hu A, Wang G, Jiao X, Zhu X, Ju W, Guo Z, He X (2018) Does ischemia free liver procurement under normothermic perfusion benefit the outcome of liver transplantation? Ann Transplant 23:258–267CrossRef
23.
go back to reference Zhao Q, Nie Y, Guo Z, He X (2019) The future of organ-oriented research and treatment. Hepatobiliary Surg Nutr 8:502–505CrossRef Zhao Q, Nie Y, Guo Z, He X (2019) The future of organ-oriented research and treatment. Hepatobiliary Surg Nutr 8:502–505CrossRef
24.
go back to reference Kaneko JJ (2013) Clinical Biochemistry of domestic animals. Academic Press, Cambridge Kaneko JJ (2013) Clinical Biochemistry of domestic animals. Academic Press, Cambridge
25.
go back to reference Liu W, Zheng X, Wu R, Jin Y, Kong S, Li J, Lu J, Yang H, Xu X, Lv Y, Zhang X (2018) Novel laparoscopic training system with continuously perfused ex-vivo porcine liver for hepatobiliary surgery. Surg Endosc 32:743–750CrossRef Liu W, Zheng X, Wu R, Jin Y, Kong S, Li J, Lu J, Yang H, Xu X, Lv Y, Zhang X (2018) Novel laparoscopic training system with continuously perfused ex-vivo porcine liver for hepatobiliary surgery. Surg Endosc 32:743–750CrossRef
26.
go back to reference Grober ED, Hamstra SJ, Wanzel KR, Reznick RK, Matsumoto ED, Sidhu RS, Jarvi KA (2004) The educational impact of bench model fidelity on the acquisition of technical skill: the use of clinically relevant outcome measures. Ann Surg 240:374–381CrossRef Grober ED, Hamstra SJ, Wanzel KR, Reznick RK, Matsumoto ED, Sidhu RS, Jarvi KA (2004) The educational impact of bench model fidelity on the acquisition of technical skill: the use of clinically relevant outcome measures. Ann Surg 240:374–381CrossRef
27.
go back to reference Strickland A, Fairhurst K, Lauder C, Hewett P, Maddern G (2011) Development of an ex vivo simulated training model for laparoscopic liver resection. Surg Endosc 25:1677–1682CrossRef Strickland A, Fairhurst K, Lauder C, Hewett P, Maddern G (2011) Development of an ex vivo simulated training model for laparoscopic liver resection. Surg Endosc 25:1677–1682CrossRef
28.
go back to reference Bittner JGT, Coverdill JE, Imam T, Deladisma AM, Edwards MA, Mellinger JD (2008) Do increased training requirements in gastrointestinal endoscopy and advanced laparoscopy necessitate a paradigm shift? A survey of program directors in surgery. J Surg Educ 65:418–430CrossRef Bittner JGT, Coverdill JE, Imam T, Deladisma AM, Edwards MA, Mellinger JD (2008) Do increased training requirements in gastrointestinal endoscopy and advanced laparoscopy necessitate a paradigm shift? A survey of program directors in surgery. J Surg Educ 65:418–430CrossRef
Metadata
Title
A new platform for laparoscopic training: initial evaluation of the ex-vivo live multivisceral training device
Authors
Xiaobo Wang
Kunsong Zhang
Wenjie Hu
Ming Kuang
Serene Teo
Zhiyong Guo
Qiang Zhao
Xiaoshun He
Publication date
01-01-2021
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 1/2021
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-020-07411-z

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