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Published in: Archives of Gynecology and Obstetrics 5/2008

01-05-2008 | Case Report

A myxoid liposarcoma arising in a leiomyoma of the uterus: a case report

Authors: Ran Hong, Sung-Chul Lim, Hyuk Jung

Published in: Archives of Gynecology and Obstetrics | Issue 5/2008

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Abstract

Background

A liposarcoma is the most frequent soft tissue sarcoma found in adults, however, a liposarcoma arising in uterus is extremely rare. Indeed, a liposarcoma coexistent with a leiomyoma is even rarer and there is only one case has been reported in the English literature to date.

Case

We describe a case of the uterine liposarcoma arising in a leiomyoma in 48-year-old woman who presented with dysmenorrhea, brownish vaginal discharge, and a rapidly enlarging lower abdominal mass. The tumor emerged from the lower segment of the endometrium and filled the endometrial cavity as a polypoid lesion. The authors of this study documented the adipocyte origin of the tumor with immunohistochemical and electron microscopical studies, the available literature was reviewed and the possible histogenesis was discussed.

Conclusion

We herein report a case of very rare primary liposarcoma arising in a submucosal uterine leiomyoma.
Literature
1.
go back to reference Fadare O (2006) Common sarcomas of the uterine cervix: a review of selected entities. Diagn Pathol 1:30–35PubMedCrossRef Fadare O (2006) Common sarcomas of the uterine cervix: a review of selected entities. Diagn Pathol 1:30–35PubMedCrossRef
2.
go back to reference Karateke A, Gurbuz A, Kabaca C, Alkan A, Kir G, Centiner H (2005) Uterine liposarcoma in a young woman: a case report. Int J Gynecol Cancer 15:1230–1234PubMedCrossRef Karateke A, Gurbuz A, Kabaca C, Alkan A, Kir G, Centiner H (2005) Uterine liposarcoma in a young woman: a case report. Int J Gynecol Cancer 15:1230–1234PubMedCrossRef
3.
go back to reference Levine PH, Wei XJ, Gagner JP, Flax H, Mittal K, Blank SV (2003) Pleomorphic liposarcoma of the uterus: case report and literature review. Int J Gynecol Pathol 22:407–411PubMedCrossRef Levine PH, Wei XJ, Gagner JP, Flax H, Mittal K, Blank SV (2003) Pleomorphic liposarcoma of the uterus: case report and literature review. Int J Gynecol Pathol 22:407–411PubMedCrossRef
4.
go back to reference Takeuchi K, Murata K, Funaki K, Fujita K, Hayakawa Y, Kitazawa S (2000) Liposarcoma of the uterine cervix: case report. Eur J Gynaecol Oncol 21:290–291PubMed Takeuchi K, Murata K, Funaki K, Fujita K, Hayakawa Y, Kitazawa S (2000) Liposarcoma of the uterine cervix: case report. Eur J Gynaecol Oncol 21:290–291PubMed
5.
go back to reference Bapat K, Brustein S (1989) Uterine sarcoma with liposarcomatous differentiation:report of a case and review of the literature. Int J Gynaecol Obstet 28:71–75PubMedCrossRef Bapat K, Brustein S (1989) Uterine sarcoma with liposarcomatous differentiation:report of a case and review of the literature. Int J Gynaecol Obstet 28:71–75PubMedCrossRef
6.
go back to reference Obafunwa JO, Uguru VE (1990) Liposarcoma of the cervix. Trop Geogr Med 42:90–91PubMed Obafunwa JO, Uguru VE (1990) Liposarcoma of the cervix. Trop Geogr Med 42:90–91PubMed
7.
go back to reference Veliath AJ, Hannah P, Ratnakar C, Jayanthi K, Aurora AL (1978) Primary liposarcoma of the cervix: a case report. Int J Gynaecol Obstet 16:75–79PubMed Veliath AJ, Hannah P, Ratnakar C, Jayanthi K, Aurora AL (1978) Primary liposarcoma of the cervix: a case report. Int J Gynaecol Obstet 16:75–79PubMed
8.
go back to reference Schneebauer J, Brinninger G, Halabi M, Nagi F (1996) Liposarcoma of the uterus. Gynakol Geburtshilfliche Rundsch 36:90–91PubMedCrossRef Schneebauer J, Brinninger G, Halabi M, Nagi F (1996) Liposarcoma of the uterus. Gynakol Geburtshilfliche Rundsch 36:90–91PubMedCrossRef
9.
go back to reference Chu PG, Arber DA, Weiss LM, Chang KL (2001) Utility of CD10 in distinguishing between endometrial stromal sarcoma and uterine smooth muscle tumors:an immunohistochemical comparison of 34 cases. Mod Pathol 14:465–471PubMedCrossRef Chu PG, Arber DA, Weiss LM, Chang KL (2001) Utility of CD10 in distinguishing between endometrial stromal sarcoma and uterine smooth muscle tumors:an immunohistochemical comparison of 34 cases. Mod Pathol 14:465–471PubMedCrossRef
10.
go back to reference Brandfass RT, Everts-Suarez EA (1955) Lipomatous tumors of the uterus: a review of the world’s literature with report of a case of true lipoma. Am J Obstet Gynecol 70:359–367PubMed Brandfass RT, Everts-Suarez EA (1955) Lipomatous tumors of the uterus: a review of the world’s literature with report of a case of true lipoma. Am J Obstet Gynecol 70:359–367PubMed
12.
go back to reference Shintaku M (1997) Lipoleiomyomatous tomours of the uterus: a heterogeneous group, Histopathological study of five cases. Pathol Int 46:498–502CrossRef Shintaku M (1997) Lipoleiomyomatous tomours of the uterus: a heterogeneous group, Histopathological study of five cases. Pathol Int 46:498–502CrossRef
13.
go back to reference Enzinger FM, Weiss SW (2001) Soft tissue tumors, 4th edn. Mosby, St Louis, pp 670–687 Enzinger FM, Weiss SW (2001) Soft tissue tumors, 4th edn. Mosby, St Louis, pp 670–687
15.
go back to reference Mittal K, Popiolek D, Demopoulos RI (2000) Uterine myxoid leiomyosarcoma within a leiomyoma. Hum Pathol 31:398–400PubMedCrossRef Mittal K, Popiolek D, Demopoulos RI (2000) Uterine myxoid leiomyosarcoma within a leiomyoma. Hum Pathol 31:398–400PubMedCrossRef
16.
go back to reference Stojsic Z, Bacetic D, Radevic B, Vasiljevic JD (2004) A well-differentiated liposarcoma co-existent with leiomyoma. Vojnosanit Pregl 61:565–568PubMed Stojsic Z, Bacetic D, Radevic B, Vasiljevic JD (2004) A well-differentiated liposarcoma co-existent with leiomyoma. Vojnosanit Pregl 61:565–568PubMed
Metadata
Title
A myxoid liposarcoma arising in a leiomyoma of the uterus: a case report
Authors
Ran Hong
Sung-Chul Lim
Hyuk Jung
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 5/2008
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-007-0486-2

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