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Published in: Archives of Gynecology and Obstetrics 5/2008

01-05-2008 | Original Article

The effects of TCu-380A on cervicovaginal flora

Authors: Mine Kanat-Pektas, Mustafa Ozat, Tayfun Gungor

Published in: Archives of Gynecology and Obstetrics | Issue 5/2008

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Abstract

Objective

This study aims to identify the alterations in cervicovaginal flora after insertion of TCu 380A which is a popular type of copper IUD.

Study design

Among the women who visited the Department of Family Planning in our hospital during 1 month, 100 subjects who preferred IUDs for contraception and who had no history of local or systemic antibiotic use were considered eligible candidates.

Results

Anaerobic colonies, especially Gram-positive cocci and Gram-negative bacilli were isolated at significantly higher rates after the insertion of TCu-380A. Aerobic colonies were isolated relatively less.

Conclusions

It can be suggested that copper IUD causes the predominance of anaerobic species in the cervicovaginal flora, which is consistent with the literature. This clinically insignificant condition can be attributed to the copper content or threads of the IUDs. Yet there is no evidence that the prevalance of pelvic infections is influenced by the use of IUDs.
Literature
1.
go back to reference Ämmälä M, Nyman T, Strengell L (1995) Effect of intrauterine contraceptive devices on cytokine messenger ribonucleic acid expression in the human endometrium. Fertil Steril 63:773PubMed Ämmälä M, Nyman T, Strengell L (1995) Effect of intrauterine contraceptive devices on cytokine messenger ribonucleic acid expression in the human endometrium. Fertil Steril 63:773PubMed
2.
go back to reference Chukudebelu WO (1980) Bacteriological study of IUDs removed from Nigerian Igbo. Int J Gynecol Obstet 17:355 Chukudebelu WO (1980) Bacteriological study of IUDs removed from Nigerian Igbo. Int J Gynecol Obstet 17:355
3.
go back to reference Everett ED, Reller LB, Droegemuller W, Greer BE (1976) Absence of bacteremia after insertion or removal of intrauterine device. Obstet Gynecol 47:207PubMed Everett ED, Reller LB, Droegemuller W, Greer BE (1976) Absence of bacteremia after insertion or removal of intrauterine device. Obstet Gynecol 47:207PubMed
4.
go back to reference Farley MM, Rosenberg MJ, Rowe PJ et al (1998) Low risk of infection from IUD use shown. Contracept Technol Update 19(8):102–103 Farley MM, Rosenberg MJ, Rowe PJ et al (1998) Low risk of infection from IUD use shown. Contracept Technol Update 19(8):102–103
5.
go back to reference Grimes DA, Schulz KF (2000) Antibiotic prophylaxis for intrauterine contraceptive device insertion. Cochrane Database Syst Rev CD001327 Grimes DA, Schulz KF (2000) Antibiotic prophylaxis for intrauterine contraceptive device insertion. Cochrane Database Syst Rev CD001327
6.
go back to reference Haukkama M (1987) Bacterial flora of the cervix in women using an intrauterine device. Contracept 36:527CrossRef Haukkama M (1987) Bacterial flora of the cervix in women using an intrauterine device. Contracept 36:527CrossRef
7.
go back to reference Mohllajee AP, Curtis KM, Petersen HB (2006) Does insertion and use of an intrauterine device increase the risk of pelvic inflammatory disease among women with sexually transmitted infection? A systematic review. Contraception 73(2):145–153PubMedCrossRef Mohllajee AP, Curtis KM, Petersen HB (2006) Does insertion and use of an intrauterine device increase the risk of pelvic inflammatory disease among women with sexually transmitted infection? A systematic review. Contraception 73(2):145–153PubMedCrossRef
8.
go back to reference Salem RM (2006) New attention to the IUD: expanding women’s contraceptive options to meet their needs. Popul Rep B (7):1–26 Salem RM (2006) New attention to the IUD: expanding women’s contraceptive options to meet their needs. Popul Rep B (7):1–26
9.
go back to reference Sivin I, Diaz S, Pavez M et al (1991) Two-year comparative trial of the gyne T380 slimline and gyne T380 intrauterine copper device. Contraception 44:481PubMedCrossRef Sivin I, Diaz S, Pavez M et al (1991) Two-year comparative trial of the gyne T380 slimline and gyne T380 intrauterine copper device. Contraception 44:481PubMedCrossRef
10.
go back to reference Sivin I, Stern J (1994) International Committee for Contraception Research. Health during prolonged use of levonorgestrel 20 mg/d and the copper TCu-380A intrauterine contraceptive devices; a multicenter study. Fertil Steril 61:70PubMed Sivin I, Stern J (1994) International Committee for Contraception Research. Health during prolonged use of levonorgestrel 20 mg/d and the copper TCu-380A intrauterine contraceptive devices; a multicenter study. Fertil Steril 61:70PubMed
11.
go back to reference Tinelli A, Tinelli R, Malvasi A et al (2006) The intrauterine device in modern contraception: still an actuality? Eur J Contracept Reprod Health Care 11(3):197–201PubMedCrossRef Tinelli A, Tinelli R, Malvasi A et al (2006) The intrauterine device in modern contraception: still an actuality? Eur J Contracept Reprod Health Care 11(3):197–201PubMedCrossRef
12.
go back to reference Tolcher R (2003) Intrauterine techniques: contentious or consensus opinion? J Fam Plann Reprod Health Care 29(1):21–24PubMedCrossRef Tolcher R (2003) Intrauterine techniques: contentious or consensus opinion? J Fam Plann Reprod Health Care 29(1):21–24PubMedCrossRef
13.
go back to reference United Nations Development Programme/United Nations Population Fund/World Health Organization/World Bank, Special Programme of Research, Development and Research Training in Human Reproduction (1997) Long-term reversible contraception. Twelve years of experience with the TCu-380A and TCu-220C. Contraception 56:341 United Nations Development Programme/United Nations Population Fund/World Health Organization/World Bank, Special Programme of Research, Development and Research Training in Human Reproduction (1997) Long-term reversible contraception. Twelve years of experience with the TCu-380A and TCu-220C. Contraception 56:341
14.
go back to reference Viberga I, Odlind V (2005) Microbiology profile in women with pelvic inflammatory disease in relation to IUD use. Infect Dis Obstet Gynecol 13(4):183–190PubMed Viberga I, Odlind V (2005) Microbiology profile in women with pelvic inflammatory disease in relation to IUD use. Infect Dis Obstet Gynecol 13(4):183–190PubMed
15.
go back to reference Wahab SA (1985) Effect of copper intrauterine device on cervicovaginal flora. Int J Gynecol Obstet 23:153CrossRef Wahab SA (1985) Effect of copper intrauterine device on cervicovaginal flora. Int J Gynecol Obstet 23:153CrossRef
Metadata
Title
The effects of TCu-380A on cervicovaginal flora
Authors
Mine Kanat-Pektas
Mustafa Ozat
Tayfun Gungor
Publication date
01-05-2008
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 5/2008
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-007-0496-0

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