Skip to main content
Top
Published in: European Radiology 4/2015

01-04-2015 | Vascular-Interventional

A multicentre retrospective study of transcatheter angiographic embolization in the treatment of delayed haemorrhage after percutaneous nephrolithotomy

Authors: Long Li, Yan Zhang, Yong Chen, Kang-Shun Zhu, De-Ji Chen, Xin-Qiao Zeng, Xiao-Bai Wang

Published in: European Radiology | Issue 4/2015

Login to get access

Abstract

Objective

The objective is to determine the timing and indications of transcatheter angiographic embolization (TAE) for delayed haemorrhage after percutaneous nephrolithotomy (PCNL).

Methods

The medical records of 144 patients who underwent arteriography and TAE for delayed post-PCNL haemorrhage at five university hospitals between January 2005 and December 2012 were reviewed retrospectively.

Results

The mean time to the onset of post-PCNL haemorrhage was 10.5 days (2 - 30 days). Clinical presentation included sudden onset bleeding in 51 patients (35.4 %), intermittent bleeding in 67 patients (46. 5 %), and continuous slow bleeding in 26 patients (18.1 %). Hemodynamic instability occurred in 32 patients (22.2 %). The mean haemoglobin decrease from the first post-PCNL day to the day of TAE was 49.5 g/L (31.0 - 79.0 g/L). Renal arteriography showed pseudoaneurysms in 69 (47.9 %) patients, arteriovenous fistulas in 28 (19.4 %) patients, mixed arterial and arteriovenous lesions in 17 (11.8 %) patients, arterial lacerations in 23 (16.0 %) patients, and negative angiographic finding in seven (4.9 %) patients. TAE was successful in stopping bleeding in all 137 patients with vascular lesions. There were no major complications associated with TAE.

Conclusions

TAE should be the recommended treatment for delayed post-PCNL haemorrhage in patients with hemodynamic instability and/or corrected haemoglobin decrease >30 g/L following conservative management.

Key Points

Delayed haemorrhage after percutaneous nephrolithotomy occurs more than 24 hours postoperatively.
Angio-embolization is a safe and effective treatment for delayed post-PCNL haemorrhage.
Angio-embolization can treat hemodynamic instability and/or corrected haemoglobin decrease >30 g/L.
Literature
1.
go back to reference Antonelli JA, Pearle MS (2013) Advances in percutaneous nephrolithotomy. Urol Clin N Am 40:99–113CrossRef Antonelli JA, Pearle MS (2013) Advances in percutaneous nephrolithotomy. Urol Clin N Am 40:99–113CrossRef
2.
go back to reference Seitz C, Desai M, Häcker A et al (2012) Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy. Eur Urol 61:146–158CrossRefPubMed Seitz C, Desai M, Häcker A et al (2012) Incidence, prevention, and management of complications following percutaneous nephrolitholapaxy. Eur Urol 61:146–158CrossRefPubMed
3.
go back to reference Keoghane SR, Cetti RJ, Rogers AE, Walmsley BH (2013) Blood transfusion, embolization and nephrectomy after percutaneous nephrolithotomy (PCNL). BJU Int 111:628–632CrossRefPubMed Keoghane SR, Cetti RJ, Rogers AE, Walmsley BH (2013) Blood transfusion, embolization and nephrectomy after percutaneous nephrolithotomy (PCNL). BJU Int 111:628–632CrossRefPubMed
4.
go back to reference Richstone L, Reggio E, Ost MC et al (2008) First Prize (tie): Hemorrhage following percutaneous renal surgery: characterization of angiographic findings. J Endourol 22:1129–1135CrossRefPubMed Richstone L, Reggio E, Ost MC et al (2008) First Prize (tie): Hemorrhage following percutaneous renal surgery: characterization of angiographic findings. J Endourol 22:1129–1135CrossRefPubMed
5.
go back to reference Li X, He Z, Wu K et al (2009) Chinese minimally invasive percutaneous nephrolithotomy: the Guangzhou experience. J Endourol 23:1693–1697CrossRefPubMed Li X, He Z, Wu K et al (2009) Chinese minimally invasive percutaneous nephrolithotomy: the Guangzhou experience. J Endourol 23:1693–1697CrossRefPubMed
6.
go back to reference Zeng GH, Zhong W, He ZH (2012) Minimally invasive percutaneous nephrolithotomy: the Chinese approach. In: Talati JJ, Tiselius HG, Albala DM, Ye ZQ (eds) Urolithiasis: Basic science and clinical practice. Springer-Verlag, London, pp 433–437CrossRef Zeng GH, Zhong W, He ZH (2012) Minimally invasive percutaneous nephrolithotomy: the Chinese approach. In: Talati JJ, Tiselius HG, Albala DM, Ye ZQ (eds) Urolithiasis: Basic science and clinical practice. Springer-Verlag, London, pp 433–437CrossRef
7.
go back to reference Zeng GH, Mai ZL, Zhao ZJ et al (2013) Treatment of upper urinary calculi with Chinese minimally invasive percutaneous nephrolithotomy: a single-center experience with 12,482 consecutive patients over 20 years. Urolithiasis 41:225–229CrossRefPubMed Zeng GH, Mai ZL, Zhao ZJ et al (2013) Treatment of upper urinary calculi with Chinese minimally invasive percutaneous nephrolithotomy: a single-center experience with 12,482 consecutive patients over 20 years. Urolithiasis 41:225–229CrossRefPubMed
8.
go back to reference Mehran R, Rao SV, Bhatt DL et al (2011) Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium. Circulation 123:2736–2747CrossRefPubMed Mehran R, Rao SV, Bhatt DL et al (2011) Standardized bleeding definitions for cardiovascular clinical trials: a consensus report from the Bleeding Academic Research Consortium. Circulation 123:2736–2747CrossRefPubMed
9.
go back to reference Katsumori T, Nakajima K, Mihara T, Tokuhiro M (2002) Uterine artery embolization using gelatin sponge particles alone for symptomatic uterine fibroids: midterm results. AJR Am J Roentgenol 178:135–139CrossRefPubMed Katsumori T, Nakajima K, Mihara T, Tokuhiro M (2002) Uterine artery embolization using gelatin sponge particles alone for symptomatic uterine fibroids: midterm results. AJR Am J Roentgenol 178:135–139CrossRefPubMed
10.
go back to reference Katsumori T, Kasahara T (2006) The size of gelatin sponge particles: differences with preparation method. Cardiovasc Intervent Radiol 29:1077–1083CrossRefPubMed Katsumori T, Kasahara T (2006) The size of gelatin sponge particles: differences with preparation method. Cardiovasc Intervent Radiol 29:1077–1083CrossRefPubMed
11.
go back to reference Siskin GP, Englander M, Stainken BF, Ahn J, Dowling K, Dolen EG (2000) Embolic agents used for uterine fibroid embolization. AJR Am J Roentgenol 175:767–773CrossRefPubMed Siskin GP, Englander M, Stainken BF, Ahn J, Dowling K, Dolen EG (2000) Embolic agents used for uterine fibroid embolization. AJR Am J Roentgenol 175:767–773CrossRefPubMed
13.
go back to reference Sacks D, McClenny TE, Cardella JF, Lewis CA (2003) Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 14:S199–S202CrossRefPubMed Sacks D, McClenny TE, Cardella JF, Lewis CA (2003) Society of Interventional Radiology clinical practice guidelines. J Vasc Interv Radiol 14:S199–S202CrossRefPubMed
14.
go back to reference Srivastava A, Singh KJ, Suri A et al (2005) Vascular complications after percutaneous nephrolithotomy: are there any predictive factors? Urology 66:38–40CrossRefPubMed Srivastava A, Singh KJ, Suri A et al (2005) Vascular complications after percutaneous nephrolithotomy: are there any predictive factors? Urology 66:38–40CrossRefPubMed
15.
go back to reference Mousavi-Bahar SH, Mehrabi S, Moslemi MK (2011) Percutaneous nephrolithotomy complications in 671 consecutive patients: a single-center experience. Urol J 8:271–276PubMed Mousavi-Bahar SH, Mehrabi S, Moslemi MK (2011) Percutaneous nephrolithotomy complications in 671 consecutive patients: a single-center experience. Urol J 8:271–276PubMed
16.
go back to reference El-Nahas AR, Shokeir AA, El-Assmy AM et al (2007) Post-percutaneous nephrolithotomy extensive hemorrhage: a study of risk factors. J Urol 177:576–579CrossRefPubMed El-Nahas AR, Shokeir AA, El-Assmy AM et al (2007) Post-percutaneous nephrolithotomy extensive hemorrhage: a study of risk factors. J Urol 177:576–579CrossRefPubMed
17.
go back to reference Nuño de la Rosa I, Palmero JL, Miralles J, Amorós A, Ferrer MD, Esteban E (2013) Treatment of hemorrhagic complications of percutaneous nephrolithotomy in Galdakao position. Actas Urol Esp 37:587–591CrossRefPubMed Nuño de la Rosa I, Palmero JL, Miralles J, Amorós A, Ferrer MD, Esteban E (2013) Treatment of hemorrhagic complications of percutaneous nephrolithotomy in Galdakao position. Actas Urol Esp 37:587–591CrossRefPubMed
18.
go back to reference Galek L, Darewicz B, Werel T, Darewicz J (2000) Haemorrhagic complications of percutaneous lithotripsy: original methods of treatment. Int Urol Nephrol 32:231–233CrossRefPubMed Galek L, Darewicz B, Werel T, Darewicz J (2000) Haemorrhagic complications of percutaneous lithotripsy: original methods of treatment. Int Urol Nephrol 32:231–233CrossRefPubMed
19.
go back to reference Breyer BN, McAninch JW, Elliott SP, Master VA (2008) Minimally invasive endovascular techniques to treat acute renal hemorrhage. J Urol 179:2248–2252CrossRefPubMed Breyer BN, McAninch JW, Elliott SP, Master VA (2008) Minimally invasive endovascular techniques to treat acute renal hemorrhage. J Urol 179:2248–2252CrossRefPubMed
20.
go back to reference Rastinehad AR, Andonian S, Smith AD, Siegel DN (2009) Management of hemorrhagic complications associated with percutaneous nephrolithotomy. J Endourol 23:1763–1767CrossRefPubMed Rastinehad AR, Andonian S, Smith AD, Siegel DN (2009) Management of hemorrhagic complications associated with percutaneous nephrolithotomy. J Endourol 23:1763–1767CrossRefPubMed
21.
go back to reference Wente MN, Veit JA, Bassi C et al (2007) Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery 142:20–25CrossRefPubMed Wente MN, Veit JA, Bassi C et al (2007) Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery 142:20–25CrossRefPubMed
22.
go back to reference Rahbari NN, Garden OJ, Padbury R et al (2011) Post-hepatectomy haemorrhage: a definition and grading by the International Study Group of Liver Surgery (ISGLS). HPB (Oxford) 13:528–535CrossRef Rahbari NN, Garden OJ, Padbury R et al (2011) Post-hepatectomy haemorrhage: a definition and grading by the International Study Group of Liver Surgery (ISGLS). HPB (Oxford) 13:528–535CrossRef
23.
go back to reference Oguz U, Resorlu B, Bayindir M, Sahin T, Bozkurt OF, Unsal A (2013) Emergent intervention criterias for controlling severe bleeding after percutaneous nephrolithotomy. ISRN Urol 2013:760272PubMedCentralPubMed Oguz U, Resorlu B, Bayindir M, Sahin T, Bozkurt OF, Unsal A (2013) Emergent intervention criterias for controlling severe bleeding after percutaneous nephrolithotomy. ISRN Urol 2013:760272PubMedCentralPubMed
24.
go back to reference Jinga V, Dorobat B, Youssef S et al (2013) Transarterial embolization of renal vascular lesions after percutaneous nephrolithotomy. Chirurgia (Bucur) 108:521–529 Jinga V, Dorobat B, Youssef S et al (2013) Transarterial embolization of renal vascular lesions after percutaneous nephrolithotomy. Chirurgia (Bucur) 108:521–529
26.
go back to reference Green RS, Edwards J, Sabri E, Fergusson D (2012) Evaluation of the incidence, risk factors, and impact on patient outcomes of post intubation hemodynamic instability. CJEM 14:74–82PubMed Green RS, Edwards J, Sabri E, Fergusson D (2012) Evaluation of the incidence, risk factors, and impact on patient outcomes of post intubation hemodynamic instability. CJEM 14:74–82PubMed
27.
go back to reference Schulman S, Angerås U, Bergqvist D et al (2010) Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients. J Thromb Haemost 8:202–204CrossRefPubMed Schulman S, Angerås U, Bergqvist D et al (2010) Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients. J Thromb Haemost 8:202–204CrossRefPubMed
29.
30.
go back to reference Sivanandam SE, Mathew G, Bhat SH (2009) Emerging role of multi-detector computed tomography in the diagnosis of hematuria following percutaneous nephrolithotomy: A case scenario. Indian J Urol 25:392–394CrossRefPubMedCentralPubMed Sivanandam SE, Mathew G, Bhat SH (2009) Emerging role of multi-detector computed tomography in the diagnosis of hematuria following percutaneous nephrolithotomy: A case scenario. Indian J Urol 25:392–394CrossRefPubMedCentralPubMed
32.
go back to reference Martin DR, Semelka RC, Chapman A et al (2009) Nephrogenic systemic fibrosis versus contrast-induced nephropathy: risks and benefits of contrast-enhanced MR and CT in renally impaired patients. J Magn Reson Imaging 30:1350–1356CrossRefPubMed Martin DR, Semelka RC, Chapman A et al (2009) Nephrogenic systemic fibrosis versus contrast-induced nephropathy: risks and benefits of contrast-enhanced MR and CT in renally impaired patients. J Magn Reson Imaging 30:1350–1356CrossRefPubMed
33.
go back to reference Lefkovitz Z, Cappell MS, Kaplan M, Mitty H, Gerard P (2000) Radiology in the diagnosis and therapy of gastrointestinal bleeding. Gastroenterol Clin N Am 29:489–512CrossRef Lefkovitz Z, Cappell MS, Kaplan M, Mitty H, Gerard P (2000) Radiology in the diagnosis and therapy of gastrointestinal bleeding. Gastroenterol Clin N Am 29:489–512CrossRef
34.
go back to reference Sofos S, Dimitrakakis G, Blake P, Pericleous A, Jackson DS, Salih M (2013) Small bowel gastrointestinal tumour: An interesting case of presentation, diagnosis and treatment. JRSM Short Rep 4:1–3CrossRefPubMedCentralPubMed Sofos S, Dimitrakakis G, Blake P, Pericleous A, Jackson DS, Salih M (2013) Small bowel gastrointestinal tumour: An interesting case of presentation, diagnosis and treatment. JRSM Short Rep 4:1–3CrossRefPubMedCentralPubMed
Metadata
Title
A multicentre retrospective study of transcatheter angiographic embolization in the treatment of delayed haemorrhage after percutaneous nephrolithotomy
Authors
Long Li
Yan Zhang
Yong Chen
Kang-Shun Zhu
De-Ji Chen
Xin-Qiao Zeng
Xiao-Bai Wang
Publication date
01-04-2015
Publisher
Springer Berlin Heidelberg
Published in
European Radiology / Issue 4/2015
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-014-3491-4

Other articles of this Issue 4/2015

European Radiology 4/2015 Go to the issue