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Journal of Orthopaedic Science

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01-07-2012 | Original Article

A comparison of tumor prosthesis implantation and pasteurized autograft-prosthesis composite for proximal tibial tumor

Authors: Won Seok Song, Wan Hyeong Cho, Dae-Geun Jeon, Chang-Bae Kong, Jian Duo, Soo-Yong Lee

Published in: Journal of Orthopaedic Science | Issue 4/2012

Abstract

Background and objectives

Although previous reports on composite biologic reconstruction in the proximal tibial location vary, we hypothesized that this type of reconstruction may reduce the late infection rate and have advantages in terms of longevity by restoring bone stock.

Methods

Primary analysis addressed differences between 62 tumor prosthesis (TP) and 25 pasteurized autograft-prosthesis composite (PPC) reconstructions in terms of survival rates, functional outcomes, and temporal patterns of infection.

Results

The 10-year survival rates of the TP and PPC groups were 73.9 ± 11.7 and 68.7 ± 20.1 %, respectively (P = 0.64). Reconstructive failure occurred in 16 (25.8 %) in the TP and in 7 (28 %) in the PPC group. The cause of failures in the TP group was infection (16), whereas those of PPC group were infection (5), loosening (1), and local recurrence (1). The mean functional scores of TP (52) and PPC (20) patients that maintained a mobile joint were 24.2 (81 %) and 25.1 (83.6 %), respectively. Infection rates in the two groups were similar (P = 0.328), but infections occurred earlier in the PPC group (P = 0.011).

Conclusions

This comparative study suggests composite biological reconstruction shows a comparable long-term survival rate to TP reconstruction; however, the composite method has a tendency to a lower rate of late infection.

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Title: A comparison of tumor prosthesis implantation and pasteurized autograft-prosthesis composite for proximal tibial tumor
Authors: Won Seok Song
Wan Hyeong Cho
Dae-Geun Jeon
Chang-Bae Kong
Jian Duo
Soo-Yong Lee
Publication date: 01-07-2012
Publisher: Springer Japan
Published in: Journal of Orthopaedic Science / Issue 4/2012
Print ISSN: 0949-2658
Electronic ISSN: 1436-2023
DOI: https://doi.org/10.1007/s00776-012-0224-x

At a glance: The STEP trials

Springer Medicine

A comparison of tumor prosthesis implantation and pasteurized autograft-prosthesis composite for proximal tibial tumor

Abstract

Background and objectives

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Background and objectives

Methods

Results

Conclusions

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