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Published in: Clinical Orthopaedics and Related Research® 2/2008

01-02-2008 | Original Article

Allograft-Prosthetic Composite in the Proximal Tibia After Bone Tumor Resection

Authors: Davide Donati, MD, Marco Colangeli, MD, Simone Colangeli, MD, Claudia Di Bella, MD, Mario Mercuri, MD

Published in: Clinical Orthopaedics and Related Research® | Issue 2/2008

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Abstract

We consider an allograft-prosthesis composite in the proximal tibia one of the better reconstructive options in this site because it combines the mechanical stability of a prosthesis with the biologic reconstruction of the extensor mechanism. We retrospectively reviewed 62 patients who had proximal tibia reconstructions with allograft-prosthesis composites to ascertain the complications and functional outcomes. By combining an allograft with a prosthesis, placing cement in the graft, and press-fitting the prosthesis in the tibial diaphysis, we obtained satisfactory Musculoskeletal Tumor Society scores in 90.4% of patients, with a 5-year survival rate (73.4%) comparable to that of reconstruction with a modular prosthesis. However, we observed high infection rates (24.2%) and rotation of the medial gastrocnemius seemed not to reduce this complication. For this reason, we do not recommend using this reconstructive technique in patients who will receive postoperative chemotherapy or in patients in whom a previous reconstructive method failed. We believe the ideal candidate is the young patient with a benign aggressive or malignant low-grade tumor who has not undergone previous surgery.
Level of Evidence: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.
Literature
1.
go back to reference Biau D, Faure F, Katsahian S, Jeanrot C, Tomeno B, Anract P. Survival of total knee replacement with a megaprosthesis after bone tumor resection. J Bone Joint Surg Am. 2006;88:1285–1293.PubMedCrossRef Biau D, Faure F, Katsahian S, Jeanrot C, Tomeno B, Anract P. Survival of total knee replacement with a megaprosthesis after bone tumor resection. J Bone Joint Surg Am. 2006;88:1285–1293.PubMedCrossRef
2.
go back to reference Biau DJ, Dumaine V, Babinet A, Tomeno B, Anract P. Allograft-prosthesis composites after bone tumor resection at the proximal tibia. Clin Orthop Relat Res. 2007;456:211–217.PubMedCrossRef Biau DJ, Dumaine V, Babinet A, Tomeno B, Anract P. Allograft-prosthesis composites after bone tumor resection at the proximal tibia. Clin Orthop Relat Res. 2007;456:211–217.PubMedCrossRef
3.
go back to reference Bickels J, Wittig JC, Kollender Y, Neff RS, Kellar-Graney K, Meller I, Malawer M. Reconstruction of the extensor mechanism after proximal tibia endoprosthetic replacement. J Arthroplasty. 2001;16:856–862.PubMedCrossRef Bickels J, Wittig JC, Kollender Y, Neff RS, Kellar-Graney K, Meller I, Malawer M. Reconstruction of the extensor mechanism after proximal tibia endoprosthetic replacement. J Arthroplasty. 2001;16:856–862.PubMedCrossRef
4.
go back to reference Brien EW, Terek RM, Healey JH, Lane JM. Allograft reconstruction after proximal tibial resection for bone tumors: an analysis of function and outcome comparing allograft and prosthetic reconstructions. Clin Orthop Relat Res. 1994;303:116–127.PubMed Brien EW, Terek RM, Healey JH, Lane JM. Allograft reconstruction after proximal tibial resection for bone tumors: an analysis of function and outcome comparing allograft and prosthetic reconstructions. Clin Orthop Relat Res. 1994;303:116–127.PubMed
5.
go back to reference Campanacci M, Costa P. Total resection of distal femur or proximal tibia for bone tumours: autogenous bone grafts and arthrodesis in twenty-six cases. J Bone Joint Surg Br. 1979;61:455–464.PubMed Campanacci M, Costa P. Total resection of distal femur or proximal tibia for bone tumours: autogenous bone grafts and arthrodesis in twenty-six cases. J Bone Joint Surg Br. 1979;61:455–464.PubMed
6.
go back to reference Clatworthy MG, Gross AE. The allograft prosthetic composite: when and how. Orthopedics. 2001;24:897–898. PubMed Clatworthy MG, Gross AE. The allograft prosthetic composite: when and how. Orthopedics. 2001;24:897–898. PubMed
7.
go back to reference Coleman W 3rd. Complicated surgical techniques: I. Flaps and grafts. Clin Dermatol. 1987;5:94–109. Coleman W 3rd. Complicated surgical techniques: I. Flaps and grafts. Clin Dermatol. 1987;5:94–109.
8.
go back to reference Currey JD, Foreman J, Laketic I, Mitchell J, Pegg DE, Reilly GC. Effects of ionizing radiation on the mechanical properties of human bone. J Orthop Res. 1997;15:111–117.PubMedCrossRef Currey JD, Foreman J, Laketic I, Mitchell J, Pegg DE, Reilly GC. Effects of ionizing radiation on the mechanical properties of human bone. J Orthop Res. 1997;15:111–117.PubMedCrossRef
9.
go back to reference Dennis DA. The structural allograft composite in revision total knee arthroplasty. J Arthroplasty. 2002;17(4 suppl 1):90–93.PubMedCrossRef Dennis DA. The structural allograft composite in revision total knee arthroplasty. J Arthroplasty. 2002;17(4 suppl 1):90–93.PubMedCrossRef
10.
go back to reference Donati D, Giacomini S, Gozzi E, Mercuri M. Proximal femur reconstruction by an allograft prosthesis composite. Clin Orthop Relat Res. 2002;394:192–200.PubMedCrossRef Donati D, Giacomini S, Gozzi E, Mercuri M. Proximal femur reconstruction by an allograft prosthesis composite. Clin Orthop Relat Res. 2002;394:192–200.PubMedCrossRef
11.
go back to reference Donati D, Giacomini S, Gozzi E, Salphale Y, Mercuri M, Mankin HJ, Springfield DS, Gebhardt MC. Allograft arthrodesis treatment of bone tumors: a two-center study. Clin Orthop Relat Res. 2002;400:217–224.PubMedCrossRef Donati D, Giacomini S, Gozzi E, Salphale Y, Mercuri M, Mankin HJ, Springfield DS, Gebhardt MC. Allograft arthrodesis treatment of bone tumors: a two-center study. Clin Orthop Relat Res. 2002;400:217–224.PubMedCrossRef
12.
go back to reference Donati D, Tella G, Gozzi E, Giacomini S, Mercuri M. The use of allograft prosthetic composite (APC) in the proximal tibia after bone tumor resection. In: Phillips GO, Strong DM, von Versen R, Nather A eds. Advances in Tissue Banking. Vol 4. Singapore: World Scientific Publishing Co Pte Ltd; 2000:313–324. Donati D, Tella G, Gozzi E, Giacomini S, Mercuri M. The use of allograft prosthetic composite (APC) in the proximal tibia after bone tumor resection. In: Phillips GO, Strong DM, von Versen R, Nather A eds. Advances in Tissue Banking. Vol 4. Singapore: World Scientific Publishing Co Pte Ltd; 2000:313–324.
13.
go back to reference Dorfman HD, Czerniak B. General considerations. In: Dorfman HD, Czerniak B, eds. Bone Tumors. St Louis, MO: CV Mosby; 1998:1. Dorfman HD, Czerniak B. General considerations. In: Dorfman HD, Czerniak B, eds. Bone Tumors. St Louis, MO: CV Mosby; 1998:1.
14.
go back to reference Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993;286:241–246.PubMed Enneking WF, Dunham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of reconstructive procedures after surgical treatment of tumors of the musculoskeletal system. Clin Orthop Relat Res. 1993;286:241–246.PubMed
15.
go back to reference Enneking WF, Eady JL, Burchardt H. Autogenous cortical bone grafts in the reconstruction of skeletal defects. J Bone Joint Surg Am. 1980;62:1039–1058.PubMed Enneking WF, Eady JL, Burchardt H. Autogenous cortical bone grafts in the reconstruction of skeletal defects. J Bone Joint Surg Am. 1980;62:1039–1058.PubMed
16.
go back to reference Farid Y, Lin PP, Lewis V, Yasko AW. Endoprosthetic and allograft prosthetic composite reconstruction of the proximal femur for bone neoplasms. Clin Orthop Relat Res. 2006;442:223–229.PubMedCrossRef Farid Y, Lin PP, Lewis V, Yasko AW. Endoprosthetic and allograft prosthetic composite reconstruction of the proximal femur for bone neoplasms. Clin Orthop Relat Res. 2006;442:223–229.PubMedCrossRef
17.
go back to reference Gerdesmeyer L, Gollwitzer H, Diehl P, Burgkart R, Steinhauser E. [Reconstruction of the extensor tendons in revision total knee arthroplasty and tumor surgery.][in German]. Orthopade. 2006;35:169–175.PubMedCrossRef Gerdesmeyer L, Gollwitzer H, Diehl P, Burgkart R, Steinhauser E. [Reconstruction of the extensor tendons in revision total knee arthroplasty and tumor surgery.][in German]. Orthopade. 2006;35:169–175.PubMedCrossRef
18.
go back to reference Gitelis S, Piasecki P. Allograft prosthetic composite arthroplasty for osteosarcoma and other aggressive bone tumors. Clin Orthop Relat Res. 1991;270:197–201.PubMed Gitelis S, Piasecki P. Allograft prosthetic composite arthroplasty for osteosarcoma and other aggressive bone tumors. Clin Orthop Relat Res. 1991;270:197–201.PubMed
19.
go back to reference Grimer RJ, Carter SR, Tillman RM, Sneath RS, Walker PS, Unwin PS, Shewell PC. Endoprosthetic replacement of the proximal tibia. J Bone Joint Surg Br. 1999;81:488–494.PubMedCrossRef Grimer RJ, Carter SR, Tillman RM, Sneath RS, Walker PS, Unwin PS, Shewell PC. Endoprosthetic replacement of the proximal tibia. J Bone Joint Surg Br. 1999;81:488–494.PubMedCrossRef
20.
go back to reference Harris AI, Poddar S, Gitelis S, Sheinkop MB, Rosenberg AG. Arthroplasty with a composite of an allograft and a prosthesis for knees with severe deficiency of bone. J Bone Joint Surg Am. 1995;77:373–386.PubMed Harris AI, Poddar S, Gitelis S, Sheinkop MB, Rosenberg AG. Arthroplasty with a composite of an allograft and a prosthesis for knees with severe deficiency of bone. J Bone Joint Surg Am. 1995;77:373–386.PubMed
21.
go back to reference Healy WL, Wasilewski SA, Takei R, Oberlander M. Patellofemoral complications following total knee arthroplasty: correlation with implant design and patient risk factors. J Arthroplasty. 1995;10:197–201.PubMedCrossRef Healy WL, Wasilewski SA, Takei R, Oberlander M. Patellofemoral complications following total knee arthroplasty: correlation with implant design and patient risk factors. J Arthroplasty. 1995;10:197–201.PubMedCrossRef
22.
go back to reference Hirn M. Long intramedullary stems of prosthetic components reduce complications, when allograft-prosthesis composite is used in tumor reconstruction. J Surg Oncol. 2002;79:201–203.PubMedCrossRef Hirn M. Long intramedullary stems of prosthetic components reduce complications, when allograft-prosthesis composite is used in tumor reconstruction. J Surg Oncol. 2002;79:201–203.PubMedCrossRef
23.
go back to reference Jeon DG, Kawai A, Boland P, Healey JH. Algorithm for the surgical treatment of malignant lesions of the proximal tibia. Clin Orthop Relat Res. 1999;358:15–26.PubMedCrossRef Jeon DG, Kawai A, Boland P, Healey JH. Algorithm for the surgical treatment of malignant lesions of the proximal tibia. Clin Orthop Relat Res. 1999;358:15–26.PubMedCrossRef
24.
go back to reference Kelly MA. Patellofemoral complications following total knee arthroplasty. Instr Course Lect. 2001;50:403–407.PubMed Kelly MA. Patellofemoral complications following total knee arthroplasty. Instr Course Lect. 2001;50:403–407.PubMed
25.
go back to reference Kroll SS, Marcadis A. Aesthetic considerations of the medial gastrocnemius myocutaneous flap. Plast Reconstr Surg. 1987;79:67–71.PubMedCrossRef Kroll SS, Marcadis A. Aesthetic considerations of the medial gastrocnemius myocutaneous flap. Plast Reconstr Surg. 1987;79:67–71.PubMedCrossRef
26.
go back to reference Le Nen D, Fabre A, Yaacoub C, Lefevre C. Flaps of the gastrocnemius muscles. Rev Chir Orthop Reparatrice Appar Mot. 1995;81:66–73.PubMed Le Nen D, Fabre A, Yaacoub C, Lefevre C. Flaps of the gastrocnemius muscles. Rev Chir Orthop Reparatrice Appar Mot. 1995;81:66–73.PubMed
27.
go back to reference Merritt K, Gaind A, Anderson JM. Detection of bacterial adherence on biomedical polymer. J Biomed Mater Res. 1998;39:415–422.PubMedCrossRef Merritt K, Gaind A, Anderson JM. Detection of bacterial adherence on biomedical polymer. J Biomed Mater Res. 1998;39:415–422.PubMedCrossRef
28.
go back to reference Natarajan MV, Sivaseelam A, Rajkumar G, Hussain SH. Custom megaprosthetic replacement for proximal tibial tumors. Int Orthop. 2003;27:334–337.PubMedCrossRef Natarajan MV, Sivaseelam A, Rajkumar G, Hussain SH. Custom megaprosthetic replacement for proximal tibial tumors. Int Orthop. 2003;27:334–337.PubMedCrossRef
29.
30.
go back to reference Rasmussen MR, Bishop AT, Wood MB. Arthrodesis of the knee with a vascularized fibular rotatory graft. J Bone Joint Surg Am. 1995;77:751–759.PubMed Rasmussen MR, Bishop AT, Wood MB. Arthrodesis of the knee with a vascularized fibular rotatory graft. J Bone Joint Surg Am. 1995;77:751–759.PubMed
31.
go back to reference Sanjay BK, Moreau PG. Limb salvage surgery in bone tumour with modular endoprosthesis. Int Orthop. 1999;23:41–46.PubMedCrossRef Sanjay BK, Moreau PG. Limb salvage surgery in bone tumour with modular endoprosthesis. Int Orthop. 1999;23:41–46.PubMedCrossRef
32.
go back to reference Shimose S, Sugita T, Kubo T, Matsuo T, Ochi M. Reconstructed patellar tendon length after proximal tibia prosthetic replacement. Clin Orthop Relat Res. 2005;439:176–180.PubMedCrossRef Shimose S, Sugita T, Kubo T, Matsuo T, Ochi M. Reconstructed patellar tendon length after proximal tibia prosthetic replacement. Clin Orthop Relat Res. 2005;439:176–180.PubMedCrossRef
33.
go back to reference Sim FH, Beauchamp CP, Chao EY. Reconstruction of musculoskeletal defects about the knee for tumor. Clin Orthop Relat Res. 1987;221:188–201.PubMed Sim FH, Beauchamp CP, Chao EY. Reconstruction of musculoskeletal defects about the knee for tumor. Clin Orthop Relat Res. 1987;221:188–201.PubMed
34.
go back to reference Snyder RJ, Doyle H, Delbridge T. Applying split-thickness skin grafts: a step-by-step clinical guide and nursing implications. Ostomy Wound Manage. 2001;47:20–26.PubMed Snyder RJ, Doyle H, Delbridge T. Applying split-thickness skin grafts: a step-by-step clinical guide and nursing implications. Ostomy Wound Manage. 2001;47:20–26.PubMed
35.
go back to reference Wunder JS, Leitch K, Griffin AM, Davis AM, Bell RS. Comparison of two methods of reconstruction for primary malignant tumors at the knee: a sequential cohort study. J Surg Oncol. 2001;77:89–99.PubMedCrossRef Wunder JS, Leitch K, Griffin AM, Davis AM, Bell RS. Comparison of two methods of reconstruction for primary malignant tumors at the knee: a sequential cohort study. J Surg Oncol. 2001;77:89–99.PubMedCrossRef
36.
go back to reference Zehr RJ, Enneking WF, Scarborough MT. Allograft-prosthesis composite versus megaprosthesis in proximal femoral reconstruction. Clin Orthop Relat Res. 1996;322:207–223.PubMedCrossRef Zehr RJ, Enneking WF, Scarborough MT. Allograft-prosthesis composite versus megaprosthesis in proximal femoral reconstruction. Clin Orthop Relat Res. 1996;322:207–223.PubMedCrossRef
Metadata
Title
Allograft-Prosthetic Composite in the Proximal Tibia After Bone Tumor Resection
Authors
Davide Donati, MD
Marco Colangeli, MD
Simone Colangeli, MD
Claudia Di Bella, MD
Mario Mercuri, MD
Publication date
01-02-2008
Publisher
Springer-Verlag
Published in
Clinical Orthopaedics and Related Research® / Issue 2/2008
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-007-0055-9

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