Published in:
01-09-2012 | Original Article
A Comparative Analysis of Hepatocellular Carcinoma after Hepatic Resection in Young versus Elderly Patients
Authors:
Cho Rok Lee, Jin Hong Lim, Sung Hoon Kim, Sang Hoon Ahn, Young Nyun Park, Gi Hong Choi, Jin Sub Choi, Kyung Sik Kim
Published in:
Journal of Gastrointestinal Surgery
|
Issue 9/2012
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Abstract
Purpose
The aim of this study was to investigate the clinical outcomes after surgical treatment of hepatocellular carcinoma (HCC) in the elderly patients compared with younger patients.
Methods
Clinicopathological data and treatment outcomes in 61 elderly (≥70 years old) and 90 younger (≤40 years old) patients with HCC who underwent curative liver resection between 2000 and 2010 were retrospectively collected and compared using various parameters.
Results
The older HCC group was more likely to have hepatitis C virus and non-B non-C hepatitis virus infection, higher values of indocyanine green retention at 15 min (ICGR)15, more preoperative comorbidities, and more postoperative complications. There were no significant differences in intraoperative parameters and pathologic features. The recurrence rate, overall survival and disease-free survival rates were similar amongst the two groups. The only independent prognostic factor of overall survival was postoperative complications.
Conclusion
Our findings suggest that age by itself does not have an adverse effect on operative outcomes, including long-term prognosis. For young and elderly HCC patients, hepatic resection is a safe and effective treatment.