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Clinical Neuroradiology
Published in: Clinical Neuroradiology 3/2014

01-09-2014 | Correspondence

A Case with Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Elevated Lactate (LBSL) with Its Characteristic Clinical and Neuroimaging Findings

Authors: H. Alibas, MD, P. K. Koytak, G. Ekinci, K. Uluc

Published in: Clinical Neuroradiology | Issue 3/2014

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Excerpt

Leukoencephalopathy with brainstem and spinal cord involvement and elevated lactate (LBSL) is a recently described white matter disorder, characterized by slowly progressive cerebellar, pyramidal, and dorsal column dysfunction [1]. It is a very rare autosomal recessive mitochondrial disease; however, its unique pattern of magnetic resonance imaging (MRI) findings distinguishes it from the other leukoencephalopathies and is therefore pathognomonic [1‐8]. Distinct MRI findings of nonhomogeneous cerebral white matter abnormalities with selective involvement of the brainstem and spinal cord and specific magnetic resonance spectroscopy (MRS) abnormalities are the striking neuroradiological features of the disease. We herein report a case of LBSL. …
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Metadata
Title
A Case with Leukoencephalopathy with Brainstem and Spinal Cord Involvement and Elevated Lactate (LBSL) with Its Characteristic Clinical and Neuroimaging Findings
Authors
H. Alibas, MD
P. K. Koytak
G. Ekinci
K. Uluc
Publication date
01-09-2014
Publisher
Springer Berlin Heidelberg
Published in
Clinical Neuroradiology / Issue 3/2014
Print ISSN: 1869-1439
Electronic ISSN: 1869-1447
DOI
https://doi.org/10.1007/s00062-013-0250-x

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