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Rheumatology International
Published in: Rheumatology International 5/2012

01-05-2012 | Case Report

A case of pulmonary sarcoidosis preceding polycythemia vera with literature review

Authors: Daniela Tirotta, Vittorio Durante

Published in: Rheumatology International | Issue 5/2012

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Abstract

For several years is described a non-random association between sarcoidosis and solid or hematological tumors. We present a case in which a patient with pulmonary sarcoidosis developed polycythemia vera few months later. A review of literature shows that sarcoidosis precedes neoplasms and tends to be a chronic active variety. Our case, by contrast, has been responsive to steroid therapy.
Literature
1.
Brincker H (1987) Solid tumors preceding or following sarcoidosis. Med Pediat Oncol 15:82–88CrossRef
2.
Ho LP, Urban BC, Thickett DR, Davies RJ, McMichael AJ (2005) Deficiency of a subset of T-cells with immunoregulatory properties in sarcoidosis. Lancet 365:1062–1072PubMed
3.
Askling J, Grunewald J, Eklund A, Hillerdal G, Ekbom A (1999) Increased risk for cancer following sarcoidosis. Am J Respir Crit Care Med 160:1668–1672PubMed
4.
5.
Reich JM, Mullooly JP, Johnson RE (1995) Linkage analysis of malignancy-associated sarcoidosis. Chest 107:605–613PubMedCrossRef
6.
Vassilakis DA, Sourvinos G, Markatos M, Psathakis K, Spandidos DA, Siafakas NM, Bouros D (1999) Microsatellite DNA instability and loss of heterozygosity in pulmonary sarcoidosis. Am J Respir Crit Care Med 160:1729–1733PubMed
7.
Brincker H, Wilbech E (1974) The incidence of malignant tumours in patients with respiratory sarcoidosis. Br J Cancer 29:247–251PubMedCrossRef
8.
Caras WE, Dillard T, Baker T, Pluss J (2003) Coexistence of sarcoidosis and malignancy. South Med J 96(9):918–922PubMedCrossRef
9.
Risbano MG, Groshong SD, Schwarz MI (2007) Lung nodules in a woman with a history of breast cancer. Chest 132:1697–1701PubMedCrossRef
10.
Gooneratne L, Nagi W, Lim Z, Ho AY, Devereux S, Pagliuca A, Mufti GJ (2008) Sarcoidosis and haematological malignancies: is there an association? Br J Haematol 141(2):260–262. (Epub 26 Feb 2008)
11.
Pascual JC, Belinchón I, Albares P, Vergara G, Betlloch I, Bañuls J (2004) Cutaneous sarcoidosis and polycythemia vera. J Eur Acad Dermatol Venereol 18(6):700–701PubMedCrossRef
12.
Brincker H (1989) Coexistence of sarcoidosis, myeloproliferative disease: a case of sarcoidosis preceding polycythaemia vera with a literature review. J Intern Med 225(5):355PubMedCrossRef
13.
Tangen JM, Naess A, Aasen T, Morild I (1988) Non-caseating granulomas in patients with hematologic malignancies. A report of three cases. Acta Med Scand 223(1):83–87PubMedCrossRef
14.
Kashyap S, Kumar M, Thakur S (1995) Sarcoidosis presenting as polycythemia. A case report. J Assoc Physicians India 43(11):795–796PubMed
15.
Askling J, Grunewald J, Eklund A, Hillerdal G, Ekbom A (1999) Increased risk for cancer following sarcoidosis. Am J Resp Crit Care Med. 160:1668–1672PubMed
16.
Boffetta P, Rabkin CS, Gridley G (2009) A cohort study of cancer among sarcoidosis patients. Int J Cancer 124(11):2697–2700PubMedCrossRef
17.
RÃmer FK (1998) Sarcoidosis and cancer revisited: a long-term follow-up study of 555 Danish sarcoidosis patients. Eur Respir J 12(4):906–912CrossRef
18.
McNeill M, Zanders TB, Morris MJ (2009) A 49-year-old man with concurrent diagnoses of lung cancer, sarcoidosis, and multiple regions of adenopathy on positron emission tomography. Chest 135(2):546–549PubMedCrossRef
19.
Yanardağ H, Pamuk GE, Karayel T, Demirci S (2002) Bone marrow involvement in sarcoidosis: an analysis of 50 bone marrow samples. Haematologia (Budap) 32(4):419–425
Metadata
Title
A case of pulmonary sarcoidosis preceding polycythemia vera with literature review
Authors
Daniela Tirotta
Vittorio Durante
Publication date
01-05-2012
Publisher
Springer-Verlag
Published in
Rheumatology International / Issue 5/2012
Print ISSN: 0172-8172
Electronic ISSN: 1437-160X
DOI
https://doi.org/10.1007/s00296-010-1378-5

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