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01-08-2011 | Case Report

^99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C

Authors: Rika Ishii, Hitoshi Togashi, Akiko Iwaba, Chikako Sato, Hiroaki Haga, Mai Sanjo, Kazuo Okumoto, Yuko Nishise, Jun-itsu Ito, Hisayoshi Watanabe, Koji Saito, Akio Okada, Kazuei Takahashi, Takafumi Saito, Sumio Kawata

Published in: Annals of Nuclear Medicine | Issue 7/2011

Abstract

We describe a 62-year-old woman with advanced chronic hepatitis C who showed no response to low-dose long-term interferon-beta monotherapy (3 MU, three times a week). The interferon monotherapy was continued for 2 years and 9 months. Despite this lack of response to interferon, the patient’s clinical course was good and liver function assessed by ^99mTc-galactosyl human serum albumin single photon emission computed tomography (^99mTc-GSA SPECT) analysis improved significantly. Improvement of the data obtained by ^99mTc-GSA SPECT analysis justified continuation of the treatment. ^99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C, despite a lack of reduction of the ALT level and HCV-RNA titer.

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Title: 99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C
Authors: Rika Ishii
Hitoshi Togashi
Akiko Iwaba
Chikako Sato
Hiroaki Haga
Mai Sanjo
Kazuo Okumoto
Yuko Nishise
Jun-itsu Ito
Hisayoshi Watanabe
Koji Saito
Akio Okada
Kazuei Takahashi
Takafumi Saito
Sumio Kawata
Publication date: 01-08-2011
Publisher: Springer Japan
Published in: Annals of Nuclear Medicine / Issue 7/2011
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI: https://doi.org/10.1007/s12149-011-0484-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

^99mTc-GSA SPECT analysis was clinically useful to evaluate the effect of interferon in a patient with interferon non-responsive chronic hepatitis C

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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