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Published in: Journal of Nuclear Cardiology 4/2022

21-03-2021 | Editorial

82Rb PET/CT left ventricular mass computations

Authors: Andrew Van Tosh, MD, Kenneth J. Nichols, MD

Published in: Journal of Nuclear Cardiology | Issue 4/2022

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Excerpt

The estimation of left ventricular (LV) mass has become an increasingly important component of standard myocardial perfusion nuclear imaging studies. This progress has been prompted by two developments. First is the growing recognition that ventricular mass and left ventricular hypertrophy (quantified in terms of LV mass and volume) play a critical role in determining cardiac prognosis for mortality, heart failure, stroke, and coronary events.1 As demonstrated in the MESA (Multi-Ethnic Study of Atherosclerosis) trial, LVH diagnosed on the basis of cardiac MR measurements predict heart failure events with an accuracy of 87%.2,3 Second are technological improvements in count rate capability and imaging spatial resolution of PET and CZT imaging systems. …
Literature
1.
go back to reference Abdi-Ali A, Miller RJH, Southern D, Zhang M, Mikami Y, Knudtson M, et al. LV mass independently predicts mortality and need for future revascularization in patients undergoing diagnostic coronary angiography. JACC Cardiovasc Imaging 2018;11:423-33.CrossRef Abdi-Ali A, Miller RJH, Southern D, Zhang M, Mikami Y, Knudtson M, et al. LV mass independently predicts mortality and need for future revascularization in patients undergoing diagnostic coronary angiography. JACC Cardiovasc Imaging 2018;11:423-33.CrossRef
2.
go back to reference Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The relationship of left ventricular mass and geometry to incident cardiovascular events: The MESA (multi-ethnic study of atherosclerosis) study. J Am Coll Cardiol 2008;52:2148-55.CrossRef Bluemke DA, Kronmal RA, Lima JAC, Liu K, Olson J, Burke GL, et al. The relationship of left ventricular mass and geometry to incident cardiovascular events: The MESA (multi-ethnic study of atherosclerosis) study. J Am Coll Cardiol 2008;52:2148-55.CrossRef
3.
go back to reference Oseni AO, Qureshi WT, Almahmoud MF, Bertoni AG, Bluemke DA, Hundley WG, et al. Left ventricular hypertrophy by ECG versus cardiac MRI as a predictor for heart failure. Heart 2017;103:49-54.CrossRef Oseni AO, Qureshi WT, Almahmoud MF, Bertoni AG, Bluemke DA, Hundley WG, et al. Left ventricular hypertrophy by ECG versus cardiac MRI as a predictor for heart failure. Heart 2017;103:49-54.CrossRef
4.
go back to reference Malahfji M, Ahmed AI, Han Y, Jung AK, Alnabelsi T, Nabi F, et al. Left ventricular mass on positron emission tomography: validation against cardiovascular magnetic resonance. J Nucl Card {current issue} Malahfji M, Ahmed AI, Han Y, Jung AK, Alnabelsi T, Nabi F, et al. Left ventricular mass on positron emission tomography: validation against cardiovascular magnetic resonance. J Nucl Card {current issue}
5.
go back to reference Ficaro EP, Lee BC, Kritzman JN, Corbett JR. Corridor4DM: the Michigan method for quantitative nuclear cardiology. J Nucl Cardiol J Nucl Cardiol 2007;14:455-65.CrossRef Ficaro EP, Lee BC, Kritzman JN, Corbett JR. Corridor4DM: the Michigan method for quantitative nuclear cardiology. J Nucl Cardiol J Nucl Cardiol 2007;14:455-65.CrossRef
6.
go back to reference Byrne C, Kjaer A, Forman JL, Hasbak P. Reproducibility of LVEF, LV volumes, and LV mass between rubidium-82 PET/CT scans in young healthy volunteers using two commercially available software packages. J Nucl Cardiol 2020;27:1237-45.CrossRef Byrne C, Kjaer A, Forman JL, Hasbak P. Reproducibility of LVEF, LV volumes, and LV mass between rubidium-82 PET/CT scans in young healthy volunteers using two commercially available software packages. J Nucl Cardiol 2020;27:1237-45.CrossRef
8.
go back to reference Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. Circulation 1977;55:613-8.CrossRef Devereux RB, Reichek N. Echocardiographic determination of left ventricular mass in man. Anatomic validation of the method. Circulation 1977;55:613-8.CrossRef
9.
go back to reference Armstrong AC, Gidding S, Gjesdal O, Wu C, Bluemke DA, Lima JA. LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice. JACC Cardiovasc Imaging 2012;5:837-48.CrossRef Armstrong AC, Gidding S, Gjesdal O, Wu C, Bluemke DA, Lima JA. LV mass assessed by echocardiography and CMR, cardiovascular outcomes, and medical practice. JACC Cardiovasc Imaging 2012;5:837-48.CrossRef
10.
go back to reference Mor-Avi V, Sugeng L, Weinert L, MacEneaney P, Caiani EG, Koch R, et al. Fast measurement of left ventricular mass with real-time three-dimensional echocardiography: comparison with magnetic resonance imaging. Circulation 2004;110:1814-8.CrossRef Mor-Avi V, Sugeng L, Weinert L, MacEneaney P, Caiani EG, Koch R, et al. Fast measurement of left ventricular mass with real-time three-dimensional echocardiography: comparison with magnetic resonance imaging. Circulation 2004;110:1814-8.CrossRef
11.
go back to reference Bellenger NG, Davies LC, Francis JM, Coats AJ, Pennell DJ. Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2000;2:271-8.CrossRef Bellenger NG, Davies LC, Francis JM, Coats AJ, Pennell DJ. Reduction in sample size for studies of remodeling in heart failure by the use of cardiovascular magnetic resonance. J Cardiovasc Magn Reson 2000;2:271-8.CrossRef
12.
go back to reference Farber NJ, Reddy ST, Doyle M, Rayarao G, Thompson DV, Olson P, et al. Ex vivo cardiovascular magnetic resonance measurements of right and left ventricular mass compared with direct mass measurement in excised hearts after transplantation: a first human SSFP comparison. Cardiovasc Magn Reson. 2014;16:74. https://doi.org/10.1186/s12968-014-0074-0.CrossRef Farber NJ, Reddy ST, Doyle M, Rayarao G, Thompson DV, Olson P, et al. Ex vivo cardiovascular magnetic resonance measurements of right and left ventricular mass compared with direct mass measurement in excised hearts after transplantation: a first human SSFP comparison. Cardiovasc Magn Reson. 2014;16:74. https://​doi.​org/​10.​1186/​s12968-014-0074-0.CrossRef
13.
go back to reference Bottini PB, Carr AA, Prisant LM, Flickinger FW, Allison JD, Gottdiener JS. Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient. Am J Hypertens 1995;8:221-8.CrossRef Bottini PB, Carr AA, Prisant LM, Flickinger FW, Allison JD, Gottdiener JS. Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient. Am J Hypertens 1995;8:221-8.CrossRef
14.
go back to reference Everett RJ, Tastet L, Clavel MA, Chin CWL, Capoulade R, Vassiliou VS, et al. Progression of hypertrophy and myocardial fibrosis in aortic stenosis: a multicenter cardiac magnetic resonance study. Circ Cardiovasc Imaging. 2018;11:CrossRef Everett RJ, Tastet L, Clavel MA, Chin CWL, Capoulade R, Vassiliou VS, et al. Progression of hypertrophy and myocardial fibrosis in aortic stenosis: a multicenter cardiac magnetic resonance study. Circ Cardiovasc Imaging. 2018;11:CrossRef
15.
go back to reference Van Tosh A, Reichek N, Cooke CD, Palestro CJ, Nichols KJ. Rb-82 PET/CT left ventricular mass-to-volume ratios. Int J Cardiovasc Imaging 2017;33:1263-70.CrossRef Van Tosh A, Reichek N, Cooke CD, Palestro CJ, Nichols KJ. Rb-82 PET/CT left ventricular mass-to-volume ratios. Int J Cardiovasc Imaging 2017;33:1263-70.CrossRef
16.
go back to reference Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J Am Coll Cardiol 1998;32:1454-9.CrossRef Haider AW, Larson MG, Benjamin EJ, Levy D. Increased left ventricular mass and hypertrophy are associated with increased risk for sudden death. J Am Coll Cardiol 1998;32:1454-9.CrossRef
17.
go back to reference Akinboboye O, Germano G, Idris O, Nichols K, Gopal A, Berman D, et al. Left ventricular mass measured by myocardial perfusion gated SPECT: relationship to three-dimensional echocardiography. J Clin Nucl Med 2003;28:392-7. Akinboboye O, Germano G, Idris O, Nichols K, Gopal A, Berman D, et al. Left ventricular mass measured by myocardial perfusion gated SPECT: relationship to three-dimensional echocardiography. J Clin Nucl Med 2003;28:392-7.
18.
go back to reference Khorsand A, Graf S, Eidherr H, Wadsak W, Kletter K, Sochor H, et al. Gated cardiac 13N-NH3 PET for assessment of left ventricular volumes, mass, and ejection fraction: Comparison with electrocardiography gated 18F-FDG PET. J Nucl Med 2005;46:2009-13.PubMed Khorsand A, Graf S, Eidherr H, Wadsak W, Kletter K, Sochor H, et al. Gated cardiac 13N-NH3 PET for assessment of left ventricular volumes, mass, and ejection fraction: Comparison with electrocardiography gated 18F-FDG PET. J Nucl Med 2005;46:2009-13.PubMed
19.
go back to reference Cherry SR, Sorenson JA, Phelps ME. Positron emission tomography. Physics in Nuclear Medicine. 4th ed. Philadelphia PA: Elsevier; 2012. p. 307-43.CrossRef Cherry SR, Sorenson JA, Phelps ME. Positron emission tomography. Physics in Nuclear Medicine. 4th ed. Philadelphia PA: Elsevier; 2012. p. 307-43.CrossRef
20.
go back to reference Johnson NP, Sdringola S, Gould KL. Partial volume correction incorporating Rb-82 positron range for quantitative myocardial perfusion PET based on systolic-diastolic activity ratios and phantom measurements. J Nucl Cardiol 2011;18:247-58.CrossRef Johnson NP, Sdringola S, Gould KL. Partial volume correction incorporating Rb-82 positron range for quantitative myocardial perfusion PET based on systolic-diastolic activity ratios and phantom measurements. J Nucl Cardiol 2011;18:247-58.CrossRef
21.
go back to reference Nichols KJ, DePuey EG, Friedman MI, Rozanski A. Do patient data ever exceed the partial volume limit? J Nucl Cardiol 1998;5:484-90.CrossRef Nichols KJ, DePuey EG, Friedman MI, Rozanski A. Do patient data ever exceed the partial volume limit? J Nucl Cardiol 1998;5:484-90.CrossRef
22.
go back to reference Galt JR, Garcia EV, Robbins WL. Effects of myocardial wall thickness of SPECT quantification. IEEE Trans Med Imaging 1990;9:144-50.CrossRef Galt JR, Garcia EV, Robbins WL. Effects of myocardial wall thickness of SPECT quantification. IEEE Trans Med Imaging 1990;9:144-50.CrossRef
23.
go back to reference Lucke C, Oppolzer B, Werner P, Foldyna B, Lurz P, Jochimsen T, et al. Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT. Eur Radiol 2017;27:5146-57.CrossRef Lucke C, Oppolzer B, Werner P, Foldyna B, Lurz P, Jochimsen T, et al. Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT. Eur Radiol 2017;27:5146-57.CrossRef
24.
go back to reference Van Tosh A, Reichek N, Phippen-Nater B, Palestro CJ, Nichols KJ. Consistency of myocardial mass computations as a quality control check on rest and stress left ventricular ejection fractions computed from (82)Rb PET data. Clin Nucl Med 2014;39:593-7.CrossRef Van Tosh A, Reichek N, Phippen-Nater B, Palestro CJ, Nichols KJ. Consistency of myocardial mass computations as a quality control check on rest and stress left ventricular ejection fractions computed from (82)Rb PET data. Clin Nucl Med 2014;39:593-7.CrossRef
26.
go back to reference Trieb T, Glodny B, Scheiblhofer M, Wolf C, Metzler B, Pachinger O, et al. Inter- and intra-rater reproducibility of semiautomatic determination of volume parameters in cardiac magnetic resonance imaging. Eur J Radiol 2008;68:476-86.CrossRef Trieb T, Glodny B, Scheiblhofer M, Wolf C, Metzler B, Pachinger O, et al. Inter- and intra-rater reproducibility of semiautomatic determination of volume parameters in cardiac magnetic resonance imaging. Eur J Radiol 2008;68:476-86.CrossRef
Metadata
Title
82Rb PET/CT left ventricular mass computations
Authors
Andrew Van Tosh, MD
Kenneth J. Nichols, MD
Publication date
21-03-2021
Publisher
Springer International Publishing
Published in
Journal of Nuclear Cardiology / Issue 4/2022
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-021-02593-y

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