Published in:
01-07-2008 | Contributions from International Congress
5.17 Effects of Chronic Angiotensin II Administration on MicroRNA Expression in Rat Cardiovascular System
Authors:
G. Castoldi, C. di Gioia, C. Bombardi, M. Mancini, M. Leopizzi, B. Corradi, G. Zerbini, A. Stella
Published in:
High Blood Pressure & Cardiovascular Prevention
|
Issue 3/2008
Login to get access
Excerpt
Introduction. Angiotensin II (Ang II) promotes hypertrophy/hyperplasia, inflammation, and fibrosis in the cardiovascular system through a complex regulation of gene expression/protein translation. MicroRNA are key regulators of gene expression and miR-1,miR-21, miR-133a, and miR-208 are involved in cardiovascular pathology. …