Published in:
01-07-2008 | Contributions from International Congress
12.14 Subcutaneous Small Resistance Artery Remodelling in Patients with Cushing’s Syndrome
Authors:
C. De Ciuceis, E. Porteri, N. Rizzardi, C. Platto, S. Paiardi, G.E.M. Boari, G.A.M. Tiberio, S.M. Giulini, D. Rizzoni, E. Agabiti Rosei
Published in:
High Blood Pressure & Cardiovascular Prevention
|
Issue 3/2008
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Excerpt
Introduction. Structural alterations of small resistance arteries in essential hypertensive patients (EH) are mostly characterized by inward eutrophic remodelling. However, we observed hypertrophic remodelling in patients with renovascular hypertension, in those with acromegaly as well as in patients with non-insulin-dependent diabetes mellitus, suggesting a relevant effect of humoral growth factors on vascular structure, even in addition to the haemodynamic load. Cortisol may stimulate the reninangiotensin system, and induce cardiac hypertrophy. However, no data are presently available about small artery structure inpatients with Cushing’s syndrome. …
