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Published in: European Journal of Nuclear Medicine and Molecular Imaging 1/2013

01-07-2013 | Review Article

11C-Choline PET/CT and PSA kinetics

Authors: Paolo Castellucci, Maria Picchio

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Special Issue 1/2013

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Abstract

The role of PET/CT with radiolabelled 18F-choline or 11C-choline in patients with prostate cancer after primary treatment has not been established yet and there are no guidelines on the appropriate use of this emerging modality. According to the literature, choline PET/CT may have a role in restaging the disease in patients with biochemical relapse for the detection of local and/or lymph node and/or distant recurrence. The aim of this brief review is to summarize the results of the most relevant published studies with particular focus on the relationship between prostate-specific antigen levels and kinetics and the sensitivity of choline PET/CT for optimizing the selection of patients who may benefit the most from this diagnostic procedure, especially early after biochemical recurrence.
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Metadata
Title
11C-Choline PET/CT and PSA kinetics
Authors
Paolo Castellucci
Maria Picchio
Publication date
01-07-2013
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue Special Issue 1/2013
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-013-2377-z

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