Top

Journal of Diabetes & Metabolic Disorders

Published in:

Open Access 01-12-2017 | Letter to the Editor

Zinc and curcumin lower arylsulfatses and some metabolic parameters in streptozotocin-induced diabetes

Authors: Mahmoud Balbaa, Marwa El-Zeftawy, Nabil Taha, Abdel-Wahab Mandour

Published in: Journal of Diabetes & Metabolic Disorders | Issue 1/2017

Abstract

In rats with induced diabetes, Zinc and curcumin treatment showed a significant increase of catalase and a significant decrease of glucose, lipid profile components and arylsulphatases activity compared to the untreated rats. We suggest that dietary zinc and curcumin are promising protective agents for reducing the metabolic defect of diabetes.

Firoozrai M, Nourbakhsh M, Razzaghy-Azar M. Erythrocyte susceptibility to oxidative stress and antioxidant status in patients with type 1 diabetes. Diabetes Res Clin Pract. 2007;77:427–32.CrossRefPubMed

Joe B, Vijaykumar M, Lokesh BR. Biolgical properties of curcumin-cellular and molecular mechanisms of action. Crit Rev Food Sci Nutr. 2009;44:97–111.CrossRef

Best L, Elliott AC, Brown PD. Curcumin induces electrical activity in rat pancreatic beta-cells by activating the volume-regulated anion channel. Biochem Pharmacol. 2007;73:1768–75.CrossRefPubMed

Jansen J, Karges W, Rink L. Zinc and diabetes- clinical links and molecular mechanisms. J Nutr Biochem. 2009;20:399–417.CrossRefPubMed

Samarji R, Balbaa M. Anti-diabetic activity of different oils through their effect on arylsulfatases. J Diabetes Metab Disord. 2014;13:116. doi:10.1186/s40200-014-0116-z.CrossRefPubMedPubMedCentral

Aebi H. Catalase in vitro. Methods Enzymol. 1984;105:121–26.CrossRefPubMed

Doumas BT, Bayse DD, Carter R, Peters Jr T, Schaffer R. A candidate reference method for determination of total protein in serum. I. Development and validation. Clin Chem. 1981;27:1642–50.PubMed

Balbaa M, El-Kersh M, Mansour H, Yacout G, Ismail M, Malky A, Bassiouny K, Abdel-Monem N, Kandeel K. Activity of some hepatic enzymes in schistosomiasis and concomitant alteration of arylsulfatase B. J Biochem Mol Biol. 2004;37:223–28.PubMed

Flegg HM. Cholesterol reagent. Ann Clin Biochem. 1973;10:79–84.CrossRef

10.

Bucolo G, David H. Quantitative determination of serum triglycerides by the use of enzymes. Clin Chem. 1973;19:476–82.PubMed

11.

Burestein M, Scholnick HR, Morfin R. Rapid method for the isolation of lipoproteins from human serum by precipitation with polyanions. J Lipid Res. 1970;11:583–93.

12.

Prasad AS. Clinical, immunological, anti-inflammatory and anti-oxidant roles of zinc. Exp Gerontol. 2008;43:370–77.CrossRefPubMed

13.

Boya P, Kroemer G. Lysosomal membrane permeabilization in cell death. Oncogene. 2008;27:6434–51.CrossRefPubMed

Title: Zinc and curcumin lower arylsulfatses and some metabolic parameters in streptozotocin-induced diabetes
Authors: Mahmoud Balbaa
Marwa El-Zeftawy
Nabil Taha
Abdel-Wahab Mandour
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: Journal of Diabetes & Metabolic Disorders / Issue 1/2017
Electronic ISSN: 2251-6581
DOI: https://doi.org/10.1186/s40200-017-0293-7

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 1/2017

Chemiluminescence systems; do all lead to same results in prolactin analysis?

Perceived cognitive deficits are associated with diabetes self-management in a multiethnic sample

Erratum to: Calcium vitamin D3 supplementation in clinical practice: side effect and satisfaction

Prevalence of metabolic syndrome and health-related quality of life in war-related bilateral lower limb amputees

Adherence to insulin self administration and associated factors among diabetes mellitus patients at Tikur Anbessa specialized hospital

Peripheral Sensory Neuropathy and associated factors among adult diabetes mellitus patients in Bahr Dar, Ethiopia

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials