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Surgical Endoscopy
Published in: Surgical Endoscopy 1/2024

20-11-2023 | Zenker's Diverticulum

Diverticular peroral endoscopic myotomy (D-POEM) for symptomatic oesophageal diverticulum: a multicentre cohort study with a minimum follow-up of 3 years

Authors: Lihua Ren, Hui Ye, Ye Zhu, Weihua Xie, Yan Liang, Yang Liu, Jingwu Dong, Weixu Chen, Xinfu Chen, Bin Wang, Liang Pan, Ruihua Shi

Published in: Surgical Endoscopy | Issue 1/2024

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Abstract

Objective

To evaluate the medium- and long-term outcomes of diverticular peroral endoscopic myotomy (D-POEM) for symptomatic oesophageal diverticulum.

Methods

Consecutive patients with symptomatic oesophageal diverticulum who underwent D-POEM from 1st May 2016 to 1st April 2020 in 6 centres were extracted and researched. Symptoms assessed by the modified Eckardt score were registered pre- and post-D-POEM at 1, 6, 12, 24 and 36 months.

Results

A total of 34 patients with Zenker’s diverticulum (ZD, n = 12), mid-oesophageal diverticulum (MED, n = 12), and epiphrenic diverticulum (ED, n = 10) were included. Complete septotomy was achieved in a mean of 39.15 min, with 100% technical success. No severe intraoperative or postoperative complications were observed. Five patients exhibited subcutaneous emphysema, while 1 had mucosal injury. The mean Eckardt score was 8.59 preoperatively and 2.56 at 1 month, 2.09 at 6 months, 2.21 at 12 months, 2.15 at 24 months, and 2.21 at 36 months postoperatively. The total clinical success rates at 1, 6, 12, 24 and 36 months postoperatively were 97.1%, 97.1%, 94.1%, 91.2%, and 88.2%, respectively. With a median follow-up of 47.2 months, four patients suffered symptom relapse, with a total clinical success rate of 88.2%. A long disease duration, a high Eckardt score, and coexistence of achalasia were identified as risk factors for symptomatic recurrence by multivariable Cox analysis.

Conclusions

D-POEM is an effective and durable treatment for patients with symptomatic oesophageal diverticulum.
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Metadata
Title
Diverticular peroral endoscopic myotomy (D-POEM) for symptomatic oesophageal diverticulum: a multicentre cohort study with a minimum follow-up of 3 years
Authors
Lihua Ren
Hui Ye
Ye Zhu
Weihua Xie
Yan Liang
Yang Liu
Jingwu Dong
Weixu Chen
Xinfu Chen
Bin Wang
Liang Pan
Ruihua Shi
Publication date
20-11-2023
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 1/2024
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-023-10471-6

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